Sigma Receptor Photolabeling and Sigma Receptor-mediated Modulation of Potassium Channels in Tumor Cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

1996 • 1,741 citations

KvLQT1 and IsK (minK) proteins associate to form the IKS cardiac potassium current

1996 • 1,585 citations

Cancer: Principles and Practice of Oncology

1997 • 1,408 citations

G Protein-coupled Receptors

1998 • 1,292 citations

Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

1996 • 880 citations

Rates of diffusional exchange between small cells and a measuring patch pipette

1988 • 712 citations

G protein-coupled mechanisms and nervous signaling

1992 • 474 citations

Cloning and Functional Expression of the Human Type 1 Sigma Receptor (hSigmaR1)

1996 • 409 citations

Signal sorting and amplification through G protein-coupled receptors

1989 • 338 citations

Cloning and Functional Characterization of a σ Receptor from Rat Brain

1998 • 288 citations

Dependence of an adenosine-activated potassium current on a GTP-binding protein in mammalian central neurons

1987 • 254 citations

Hormone production by cultures of small-cell carcinoma of the lung

1981 • 200 citations

Cloning and Structural Analysis of the cDNA and the Gene Encoding the Murine Type 1 Sigma Receptor

1997 • 199 citations

Isolation and growth characteristics of continuous cell lines from small-cell carcinoma of the lung

1980 • 182 citations

Three potassium channels in rat posterior pituitary nerve terminals.

1992 • 104 citations

Delineating biochemical and functional properties of sigma receptors: emerging concepts.

1993 • 99 citations

Phosphorylation and dephosphorylation modulate a Ca(2+)‐activated K+ channel in rat peptidergic nerve terminals.

1994 • 89 citations

A Prospective Study of Patients with Lung Cancer and Hyponatremia of Malignancy

1997 • 75 citations

Compounds selective for dopamine receptor subtypes

1997 • 73 citations

Electrophysiological and binding studies on intact NCB-20 cells suggest presence of a low affinity sigma receptor.

1991 • 68 citations

K⁺ channel modulation in rodent neurohypophysial nerve terminals by sigma receptors and not by dopamine receptors

1999 • 62 citations

The Sigma Receptor Ligand, Reduced Haloperidol, Induces Apoptosis and Increases Intracellular-Free Calcium Levels [Ca2+]iin Colon and Mammary Adenocarinoma Cells

1996 • 59 citations

Voltage-activated K+ conductance and cell proliferation in small-cell lung cancer

1994 • 55 citations

G protein interaction with K+ and Ca2+ channels

1997 • 55 citations

(125I)iodoazidococaine, a photoaffinity label for the haloperidol-sensitive sigma receptor.

1992 • 53 citations

Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells.

1995 • 49 citations

Mechanisms of K + Channel Regulation

1996 • 49 citations

Sigma ligands stimulate the electrical activity of frog pituitary melanotrope cells through a G-protein-dependent inhibition of potassium conductances.

1998 • 45 citations

Proteins that interact with the pore-forming subunits of voltage-gated ion channels

1995 • 34 citations

Dopamine D4 receptor mediated inhibition of potassium current in neurohypophysial nerve terminals.

1998 • 28 citations

Characterization of the currents induced by sigma ligands in NCB20 neuroblastoma cells

1994 • 20 citations

α ₁ and α ₂ Ca ²⁺ channel subunit expression in human neuronal and small cell carcinoma cells

1994 • 11 citations