Suppression of experimental autoimmune encephalomyelitis by extracellular adherence protein of Staphylococcus aureus

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

IMMUNOLOGY OF MULTIPLE SCLEROSIS

2005 • 2,099 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins

2003 • 556 citations

Shear forces promote lymphocyte migration across vascular endothelium bearing apical chemokines

2001 • 398 citations

Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytes.

1991 • 388 citations

Junctional complexes of the blood–brain barrier: permeability changes in neuroinflammation

2002 • 352 citations

Leukocyte traffic in the central nervous system: the participants and their roles

1999 • 348 citations

Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia

2004 • 311 citations

Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab

2005 • 298 citations

Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1–deficient mice

2002 • 290 citations

Antibodies to CD44 and integrin α₄, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment

1999 • 287 citations

Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1–deficient mice

2002 • 261 citations

Staphylococcus aureus extracellular adherence protein serves as anti-inflammatory factor by inhibiting the recruitment of host leukocytes

2002 • 257 citations

Molecules involved in T-cell costimulation

1993 • 237 citations

Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis.

1998 • 229 citations

P-selectin and vascular cell adhesion molecule 1 mediate rolling and arrest, respectively, of CD4+ T lymphocytes on tumor necrosis factor α-activated vascular endothelium under flow.

1995 • 223 citations

Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM‐1

1993 • 186 citations

Staphylococcus aureus interactions with the endothelium

2005 • 183 citations

The Junctional Adhesion Molecule-C Promotes Neutrophil Transendothelial Migration in Vitro and in Vivo

2004 • 183 citations

Cutting Edge Commentary: Chemokine Regulation of Experimental Autoimmune Encephalomyelitis: Temporal and Spatial Expression Patterns Govern Disease Pathogenesis

1998 • 182 citations

ICAM-1 co-stimulates target cells to facilitate antigen presentation

2005 • 180 citations

Increased levels of circulating ICAM-1 in serum and cerebrospinal fluid of patients with active multiple sclerosis. Correlation with TNF-α and blood-brain barrier damage

1993 • 180 citations

Expression of Functional Selectin Ligands on Th Cells Is Differentially Regulated by IL-12 and IL-4

1999 • 140 citations

The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell–mediated responses

2002 • 125 citations

Bothanti-CD11a(LFA-l) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis

1995 • 120 citations

The adhesive and immunomodulating properties of the multifunctional Staphylococcus aureus protein Eap

2003 • 116 citations

An optimized system for expression and purification of secreted bacterial proteins

2005 • 114 citations

Discordant effects of anti–VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis

2001 • 113 citations

Is damage in central nervous system due to inflammation?

2004 • 107 citations

The central nervous system environment controls effector CD4⁺ T cell cytokine profile in experimental allergic encephalomyelitis

1997 • 106 citations

Anti-adhesion molecule therapy in experimental autoimmune encephalomyelitis

1993 • 102 citations

Clinical features and diagnosis of multiple sclerosis

2005 • 102 citations

The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell–mediated responses

2002 • 99 citations

Migration of Leukocytes across Endothelial Junctions: Some Concepts and Controversies

2001 • 86 citations

Analysis of lymphocyte costimulation in vivo using transgenic and 'knockout' mice

1995 • 84 citations

Encephalitogenic T?cells use LFA-1 for transendothelial migration but not during capture and initial adhesion strengthening in healthy spinal cord microvesselsin vivo

2002 • 79 citations

The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens

2005 • 73 citations

Elastase Release by Transmigrating Neutrophils Deactivates Endothelial-bound SDF-1α and Attenuates Subsequent T Lymphocyte Transendothelial Migration

2004 • 70 citations

Brain microvascular endothelial cells and leukocytes derived from patients with multiple sclerosis exhibit increased adhesion capacity

1997 • 45 citations

Role of chemokines in the regulation of Th1/Th2 and autoimmune encephalomyelitis.

1999 • 43 citations

The use of animal models to investigate the pathogenesis of neuroinflammatory disorders of the central nervous system

2003 • 40 citations

Experimental Autoimmune Encephalomyelitis in Intercellular Adhesion Molecule-1-Deficient Mice

1998 • 36 citations

Health outcomes in multiple sclerosis

2004 • 14 citations