Encephalitogenic T?cells use LFA-1 for transendothelial migration but not during capture and initial adhesion strengthening in healthy spinal cord microvesselsin vivo
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References (35)
α4 integrins mediate lymphocyte attachment and rolling under physiologic flow
1995 • 1,018 citations
The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.
1995 • 716 citations
Distinct roles of L-selectin and integrins α4β7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: The multistep model confirmed and refined
1995 • 520 citations
Chemokines Trigger Immediate β2 Integrin Affinity and Mobility Changes
2000 • 517 citations
Divalent cation regulation of the function of the leukocyte integrin LFA-1.
1992 • 492 citations
Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytes.
1991 • 388 citations
Immunological Aspects of Experimental Allergic Encephalomyelitis and Multiple Sclerosis
1995 • 381 citations
Avidity regulation of integrins: the driving force in leukocyte adhesion
2000 • 342 citations
α4-integrin-VCAM-1 binding mediates G protein–independent capture of encephalitogenic T cell blasts to CNS white matter microvessels
2001 • 330 citations
The involvement of lipid rafts in the regulation of integrin function
2002 • 302 citations
Endothelial, not hemodynamic, differences are responsible for preferential leukocyte rolling in rat mesenteric venules.
1991 • 259 citations
Are changes in integrin affinity and conformation overemphasized?
1998 • 257 citations
Regulation of leukocyte integrin function: Affinity vs. avidity
1996 • 244 citations
L-selectin function is required for beta 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo
1992 • 239 citations
Inhibition of mixed lymphocyte response by a rat monoclonal antibody to a novel murine lymphocyte activation antigen (MALA-2).
1985 • 229 citations
Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse.
1994 • 216 citations
The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin.
1998 • 204 citations
Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM‐1
1993 • 186 citations
Lymphocyte adhesion and transendothelial migration in the central nervous system: the role of LFA-1, ICAM-1, VLA-4 and VCAM-1. off.
1995 • 178 citations
T cell interaction with ICAM-1-deficient endotheliumin vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells
1998 • 174 citations
E- and P-Selectin Are Not Involved in the Recruitment of Inflammatory Cells Across the Blood-Brain Barrier in Experimental Autoimmune Encephalomyelitis
1997 • 171 citations
Interaction of α4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro
2000 • 143 citations
Integrin Cross Talk: Activation of Lymphocyte Function-associated Antigen-1 on Human T Cells Alters α4β1- and α5β1-mediated Function
1997 • 139 citations
α4β1 Integrin/VCAM-1 Interaction Activates αLβ2 Integrin-Mediated Adhesion to ICAM-1 in Human T Cells
2000 • 129 citations
The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion
2000 • 126 citations
Bothanti-CD11a(LFA-l) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis
1995 • 120 citations
Anti-adhesion molecule therapy in experimental autoimmune encephalomyelitis
1993 • 102 citations
ICAM-1-dependent pathway is not critically involved in the inflammatory process of autoimmune encephalomyelitis or in cytokine-induced inflammation of the central nervous system
1993 • 75 citations
Augmentation of adoptively transferred experimental allergic encephalomyelitis by administration of a monoclonal antibody specific for LFA-1α
1993 • 74 citations
T cell interaction with ICAM-1-deficient endothelium in vitro: transendothelial migration of different T cell populations is mediated by endothelial ICAM-1 and ICAM-2
1999 • 67 citations
Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the beta2 integrin leukocyte function-associated antigen-1.
1996 • 67 citations
Suppression of experimental allergic neuritis by an antibody to the intercellular adhesion molecule ICAM-1
1993 • 61 citations
Role of adhesion molecules in activation signaling in T lymphocytes.
2001 • 58 citations
Antibodies against Leukocyte Function-Associated Antigen-1 and against Intercellular Adhesion Molecule-1 Together Suppress the Progression of Experimental Allergic Encephalomyelitis
1995 • 56 citations
Intrathecal Administration of Antibodies against LFA-1 and against ICAM-1 Suppresses Experimental Allergic Encephalomyelitis in Rats
1996 • 44 citations
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