Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1–deficient mice

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1990 • 2,129 citations

PECAM-1 is required for transendothelial migration of leukocytes.

1993 • 1,134 citations

PECAM-1 (CD31) Cloning and Relation to Adhesion Molecules of the Immunoglobulin Gene Superfamily

1990 • 948 citations

Selective Requirement for Src Kinases during VEGF-Induced Angiogenesis and Vascular Permeability

1999 • 802 citations

Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule.

1991 • 719 citations

Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells

1998 • 695 citations

A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H‐2^b mice: Fine specificity and T cell receptor Vβ expression of encephalitogenic T cells

1995 • 600 citations

Involvement of Platelet-Endothelial Cell Adhesion Molecule-1 in Neutrophil Recruitment in Vivo

1993 • 468 citations

Genetic Evidence for Functional Redundancy of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1): CD31-Deficient Mice Reveal PECAM-1-Dependent and PECAM-1-Independent Functions

1999 • 430 citations

EndoCAM: a novel endothelial cell-cell adhesion molecule.

1990 • 409 citations

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion.

1992 • 383 citations

A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions.

1989 • 365 citations

Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases.

1994 • 338 citations

Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo.

1994 • 296 citations

Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1.

1995 • 240 citations

Animal models of human disease Experimental autoimmune encephalomyelitis in rodents as a model for human demyelinating disease

1995 • 218 citations

Molecular characterization and functional analysis of the leukocyte surface protein CD31.

1990 • 217 citations

The Protein-tyrosine Phosphatase SHP-2 Binds Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Forms a Distinct Signaling Complex during Platelet Aggregation

1997 • 215 citations

Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin.

1997 • 209 citations

The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin.

1998 • 204 citations

An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane.

1996 • 198 citations

Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells.

1994 • 196 citations

Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans

1993 • 180 citations

Roles of platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) in natural killer cell transendothelial migration and beta 2 integrin activation.

1996 • 180 citations

T cell interaction with ICAM-1-deficient endotheliumin vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells

1998 • 174 citations

A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31).

1992 • 160 citations

Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells.

1997 • 155 citations

A New Role for Platelet-Endothelial Cell Adhesion Molecule-1 (CD31): Inhibition of TCR-Mediated Signal Transduction

1999 • 154 citations

Interaction of α4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro

2000 • 143 citations

Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution.

1992 • 137 citations

Murine platelet endothelial cell adhesion molecule (PECAM‐1)/CD31 modulates β₂ integrins on lymphokine‐activated killer cells

1993 • 131 citations

Biochemistry and expression of myelomonocytic antigens.

1986 • 129 citations

PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated β-catenin

1999 • 126 citations

Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56lck

2001 • 126 citations

PECAM-1 (CD31) Expression Modulates Bleeding Time in Vivo

2000 • 116 citations

Antibodies Against the First Ig-Like Domain of Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Inhibit PECAM-1-Dependent Homophilic Adhesion Block In Vivo Neutrophil Recruitment

2000 • 110 citations

Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts.

1995 • 110 citations

The Protein-tyrosine Phosphatase SHP-2 Associates with Tyrosine-phosphorylated Adhesion Molecule PECAM-1 (CD31)

1997 • 106 citations

PECAM-1/CD31 Trans-homophilic Binding at the Intercellular Junctions Is Independent of Its Cytoplasmic Domain; Evidence for Heterophilic Interaction with Integrin αvβ3 in Cis

2000 • 104 citations

Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1.

1996 • 102 citations

Platelet Endothelial Cell Adhesion Molecule-1 Is Phosphorylatable by c-Src, Binds Src-Src homology 2 Domain, and Exhibits Immunoreceptor Tyrosine-based Activation Motif-like Properties

1997 • 99 citations

A novel leukocyte differentiation antigen: two monoclonal antibodies TM2 and TM3 define a 120-kd molecule present on neutrophils, monocytes, platelets, and activated lymphoblasts

1985 • 96 citations

The cell adhesion molecule CD31 is phosphorylated after cell activation. Down-regulation of CD31 in activated T lymphocytes.

1992 • 93 citations

Molecular cloning and adhesive properties of murine platelet/endothelial cell adhesion molecule 1.

1993 • 90 citations

Distinct roles for matrix metalloproteinase-2 and α4 integrin in autoimmune T cell extravasation and residency in brain parenchyma during experimental autoimmune encephalomyelitis

2000 • 87 citations

Studies of lymphocyte transendothelial migration: analysis of migrated cell phenotypes with regard to CD31 (PECAM-1), CD45RA and CD45RO.

1993 • 80 citations

The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis.

1998 • 66 citations

The molecular basis for the assembly and modulation of adherens-type junctions

1990 • 62 citations

Aggregation of the High Affinity IgE Receptor Results in the Tyrosine Phosphorylation of the Surface Adhesion Protein PECAM-1 (CD31)

1997 • 58 citations

PECAM-1 (CD31) expression in the central nervous system and its role in experimental allergic encephalomyelitis in the rat

1996 • 56 citations

Ligation of CD31/PECAM-1 modulates the function of lymphocytes, monocytes and neutrophils

1998 • 54 citations

Expression of CD31 epitopes on human lymphocytes: CD31 monoclonal antibodies differentiate between naive (CD45RA⁺) and memory (CD45RA^‐) CD4‐positive T cells

1991 • 46 citations

CD31‐triggered rearrangement of the actin cytoskeleton in human natural killer cells

1996 • 43 citations

Organ-specific change inDolichos biflorus lectin binding by myocardial endothelial cells during in vitro cultivation

1993 • 18 citations

Vasoactive agents modulate migration of monocytes across glomerular endothelial cells.

2000 • 10 citations