Lysophosphatidic acid in neural signaling

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Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

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Chemotropic Responses of Retinal Growth Cones Mediated by Rapid Local Protein Synthesis and Degradation

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Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex.

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Rho Family GTPases and Neuronal Growth Cone Remodelling: Relationship between Increased Complexity Induced by Cdc42Hs, Rac1, and Acetylcholine and Collapse Induced by RhoA and Lysophosphatidic Acid

1997 • 601 citations

Lysophospholipids--Receptor Revelations

2001 • 539 citations

Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid

1999 • 536 citations

Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid

1999 • 517 citations

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1‐phosphate

1998 • 516 citations

Requirement for the lp _A1 lysophosphatidic acid receptor gene in normal suckling behavior

2000 • 468 citations

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1991 • 464 citations

Bioactive Lysophospholipids and Their G Protein-Coupled Receptors

1999 • 412 citations

Lysophosphatidic Acid Receptors

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1997 • 384 citations

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Lysophospholipid Receptors

2001 • 319 citations

Phosphorylation of Collapsin Response Mediator Protein-2 by Rho-kinase

2000 • 315 citations

Activation of RhoA by Lysophosphatidic Acid and Gα_12/13Subunits in Neuronal Cells: Induction of Neurite Retraction

1999 • 303 citations

Modulation of NMDA receptor function: implications for vertebrate neural development

1994 • 286 citations

A single receptor encoded by vzg-1 / lp _A1 / edg- 2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid

1998 • 280 citations

Assembly of Phospholipids into Cellular Membranes: Biosynthesis, Transmembrane Movement and Intracellular Translocation

1988 • 267 citations

NMDA Receptor and the Tyrosine Phosphorylation of Its 2B Subunit in Taste Learning in the Rat Insular Cortex

1997 • 235 citations

Molecular Cloning of the Human Edg2 Protein and Its Identification as a Functional Cellular Receptor for Lysophosphatidic Acid

1997 • 232 citations

Stimulation of actin stress fibre formation mediated by activation of phospholipase D

1996 • 215 citations

Molecular Cloning and Characterization of a Lysophosphatidic Acid Receptor, Edg-7, Expressed in Prostate

2000 • 206 citations

Functional Comparisons of the Lysophosphatidic Acid Receptors, LP_A1/VZG-1/EDG-2, LP_A2/EDG-4, and LP_A3/EDG-7 in Neuronal Cell Lines Using a Retrovirus Expression System

2000 • 206 citations

Lysophosphatidic acid receptor genevzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain

1998 • 180 citations

Lysophosphatidic Acid (LPA) Is a Novel Extracellular Regulator of Cortical Neuroblast Morphology

2000 • 170 citations

The Neurite Retraction Induced by Lysophosphatidic Acid Increases Alzheimer's Disease-like Tau Phosphorylation

1999 • 170 citations

Lysophosphatidic acid as a phospholipid mediator: pathways of synthesis

1997 • 169 citations

Regulation of Schwann Cell Morphology and Adhesion by Receptor-Mediated Lysophosphatidic Acid Signaling

2001 • 169 citations

Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of RhoA

1997 • 155 citations

Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate

2002 • 154 citations

Regulation of Astrocyte Morphology by RhoA and Lysophosphatidic Acid

1998 • 153 citations

A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs)

1999 • 153 citations

Lysophosphatidic acid possesses dual action in cellproliferation.

1994 • 151 citations

Lysophosphatidic Acid Influences the Morphology and Motility of Young, Postmitotic Cortical Neurons

2002 • 140 citations

The LPA receptors

2001 • 121 citations

In vivo roles of lysophospholipid receptors revealed by gene targeting studies in mice

2002 • 108 citations

Role of lysophosphatidic acid and Rho in glioma cell motility

2000 • 104 citations

Phospholipase D Activity Is Required for Actin Stress Fiber Formation in Fibroblasts

2001 • 102 citations

Astrocyte spreading in response to thrombin and lysophosphatidic acid is dependent on the Rho GTPase

1997 • 100 citations

Occurrence of lysophosphatidic acid and its alkyl ether-linked analog in rat brain and comparison of their biological activities toward cultured neural cells

1999 • 98 citations

The role of nitric oxide and NMDA receptors in the development of motor neuron dendrites.

1998 • 96 citations

Scanning and transmission electron microscope studies of interkinetic nuclear migration in the cerebral vesicles of the rat

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The Role of Nitric Oxide and NMDA Receptors in the Development of Motor Neuron Dendrites

1998 • 89 citations

NMDA receptor activation results in tyrosine phosphorylation of NMDA receptor subunit 2A(NR2A) and interaction of Pyk2 and Src with NR2A after transient cerebral ischemia and reperfusion

2001 • 86 citations

Genomic Characterization of the Lysophosphatidic Acid Receptor Gene, lpA2/Edg4, and Identification of a Frameshift Mutation in a Previously Characterized cDNA

2000 • 83 citations

Lysophospholipid Receptors: Implications for Neural Signaling

1999 • 83 citations

Quantification, characterization and fatty acid composition of lysophosphatidic acid in different rat tissues

1989 • 83 citations

Lysophosphatidic Acid Stimulates Neurotransmitter-Like Conductance Changes that Precede GABA and l-Glutamate in Early, Presumptive Cortical Neuroblasts

1999 • 80 citations

Lysophospholipids and the cardiovascular system

2002 • 74 citations

Clonal Cell Lines Produced by Infection of Neocortical Neuroblasts Using Multiple Oncogenes Transduced by Retroviruses

1996 • 68 citations

Purification of a phosphatidic-acid-hydrolysing phospholipase A2 from rat brain

1995 • 62 citations

Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve endings in mice

1999 • 59 citations

Expression of lysophosphatidic acid receptor in rat astrocytes: mitogenic effect and expression of neurotrophic genes.

2000 • 57 citations

Neurotransmitter Release from Lysophosphatidic Acid-Stimulated PC12 Cells: Involvement of Lysophosphatidic Acid Receptors

1993 • 57 citations

Lysophosphatidic acid stimulates actomyosin contraction in astrocytes

1998 • 57 citations

Chronic NMDA Exposure Accelerates Development of GABAergic Inhibition in the Superior Colliculus

2000 • 54 citations

Regulation of ET-1 biosynthesis in cerebral microvascular endothelial cells by vasoactive agents and PKC

1999 • 54 citations

Vzg-1/lysophosphatidic acid-receptor involved in peripheral pain transmission

2000 • 50 citations

Bovine serum albumin and lysophosphatidic acid stimulate calcium mobilization and reversal of cAMP-induced stellation in rat spinal cord astrocytes

1997 • 50 citations

Inhibition of Na+, K+ -ATPase Activity by Phospholipase A2 and Several Lysophospholipids: Possible Role of Phospholipase A2 in Noradrenaline Release from Cerebral Cortical Synaptosomes

1989 • 39 citations

Effects of lysophosphatidic acid on primary cultured chick neurons

1997 • 38 citations

Lysophosphatidic acid-induced calcium signals in cultured rat oligodendrocytes

1999 • 36 citations

Pleiotropic effects of lysophosphatidic acid on striatal astrocytes

1999 • 34 citations

Cell Culture Studies of the Role of Elevated Extracellular Glutamate and K+ in Neuronal Cell Death During and After Anoxia/Ischemia

1997 • 30 citations

Lysophosphatidic acid stimulates proliferation of human retinal pigment epithelial cells

1997 • 20 citations

Lysophosphatidic acid-induced Ca2+ mobilization in the neural retina of chick embryo

1999 • 19 citations

Characterization of epidermal growth factor receptor function in Lysophosphatidic acid signaling in PC12 cells

2000 • 17 citations

Lysophosphatidic Acid Stimulates Two Ion Currents in Cultured Human Retinal Pigment Epithelial Cells

1997 • 12 citations

Involvement of calcium in retinal pigment epithelial cell proliferation and pigmentation

1998 • 12 citations

Acute neurite retraction triggered by lysophosphatidic acid: timing of the inhibitory effects of genistein

1994 • 10 citations