Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of RhoA

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

1997 • 1,085 citations

The p160 RhoA-Binding Kinase ROKα Is a Member of a Kinase Family and Is Involved in the Reorganization of the Cytoskeleton

1996 • 866 citations

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

1994 • 617 citations

Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger

1995 • 592 citations

Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.

1994 • 469 citations

Post-translational modifications of p21rho proteins.

1992 • 422 citations

Intracellular localization of the P21rho proteins.

1992 • 382 citations

Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells.

1992 • 355 citations

Rho: theme and variations

1996 • 290 citations

Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor.

1996 • 280 citations

Rho: a connection between membrane receptor signalling and the cytoskeleton

1996 • 271 citations

Rho family GTPases: the cytoskeleton and beyond

1996 • 262 citations

Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.

1994 • 245 citations

Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors

1992 • 245 citations

Guanine nucleotide exchange factors: Activators of the Ras superfamily of proteins

1995 • 217 citations

Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells.

1996 • 215 citations

Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action.

1993 • 210 citations

Lysophosphatidic Acid‐Induced Neurite Retraction in PC12 Cells: Control by Phosphoinositide‐Ca²⁺ Signaling and Rho

1996 • 198 citations

Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows.

1995 • 192 citations

Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers.

1992 • 188 citations

Massive Actin Polymerization Induced by Phosphatidylinositol-4-phosphate 5-Kinase in Vivo

1997 • 174 citations

Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells.

1995 • 166 citations

Identification of a Novel, Putative Rho-specific GDP/GTP Exchange Factor and a RhoA-binding Protein: Control of Neuronal Morphology

1997 • 154 citations

Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin

1996 • 152 citations

Differential Translocation of Rho Family GTPases by Lysophosphatidic Acid, Endothelin-1, and Platelet-derived Growth Factor

1996 • 151 citations

The Rho's progress: a potential role during neuritogenesis for the Rho family of GTPases

1995 • 129 citations

Lfc and Lsc Oncoproteins Represent Two New Guanine Nucleotide Exchange Factors for the Rho GTP-binding Protein

1996 • 125 citations

A novel role for RhoGDI as an inhibitor of GAP proteins.

1993 • 117 citations

Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

1994 • 104 citations

C-terminal Truncation of the Neurokinin-2 Receptor Causes Enhanced and Sustained Agonist-induced Signaling

1995 • 76 citations

rho gene products, botulinum C3 exoenzyme and cell adhesion

1993 • 57 citations

Morphological Effects, Rate of Incorporation, and the Enzymatic Action of Botulinum ADP‐Ribosyltransferase, Known as C3 Exoenzyme, on Human Neuroblastoma GOTO Cells

1994 • 12 citations