A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs)

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

A novel multigene family may encode odorant receptors: A molecular basis for odor recognition

1991 • 4,793 citations

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1995 • 2,837 citations

[22] Using CLUSTAL for multiple sequence alignments

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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Autoradiographic Study of Cell Migration during Histogenesis of Cerebral Cortex in the Mouse

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A second endogenous cannabinoid that modulates long-term potentiation

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Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

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Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex.

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Embryonic vertebrate central nervous system: Revised terminology

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Sphingolipid metabolism and cell growth regulation

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Mitosis in the neural tube

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Selective Amplification And Cloning Of Four New Members Of The G Protein-coupled Receptor Family

1989 • 647 citations

Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger

1995 • 592 citations

Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary model

1995 • 572 citations

Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex

1996 • 540 citations

Lysophosphatidic acid: G-protein signalling and cellular responses

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ESTABLISHMENT OF FUNCTIONAL CLONAL LINES OF NEURONS FROM MOUSE NEUROBLASTOMA

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Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis

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An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors.

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Cell proliferation and migration in the primitive ependymal zone; An autoradiographic study of histogenesis in the nervous system

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Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

1978 • 431 citations

Cloning and growth of multipotential neural precursors: Requirements for proliferation and differentiation

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Brain basic fibroblast growth factor stimulates the proliferation of rat neuronal precursor cells in vitro

1987 • 336 citations

A Neuroblastoma × Glioma Hybrid Cell Line with Morphine Receptors

1974 • 316 citations

Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor.

1996 • 280 citations

A single receptor encoded by vzg-1 / lp _A1 / edg- 2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid

1998 • 280 citations

Involvement of Sphingosine 1-Phosphate in Nerve Growth Factor-Mediated Neuronal Survival and Differentiation

1997 • 278 citations

Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1

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Identification of cDNAs encoding two G protein‐coupled receptors for lysosphingolipids¹

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Programmed cell death is a universal feature of embryonic and postnatal neuroproliferative regions throughout the central nervous system

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Molecular Cloning of the Human Edg2 Protein and Its Identification as a Functional Cellular Receptor for Lysophosphatidic Acid

1997 • 232 citations

Lysophosphatidic acid signalling

1995 • 223 citations

Sphingosine 1-Phosphate Induces Platelet Activation through an Extracellular Action and Shares a Platelet Surface Receptor with Lysophosphatidic Acid

1997 • 200 citations

Computer-aided three-dimensional reconstruction and quantitative analysis of cells from serial electron microscopic montages of foetal monkey brain

1974 • 186 citations

Lysophosphatidic acid receptor genevzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain

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Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes

1996 • 173 citations

Lysophosphatidic acid as a phospholipid mediator: pathways of synthesis

1997 • 169 citations

The Inducible G Protein-coupled Receptor edg-1 Signals via the Gi/Mitogen-activated Protein Kinase Pathway

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Effects of synthetic and natural lysophosphatidic acids on the arterial blood pressure of different animal species

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bFGF, neurotrophins, and the control of cortical neurogenesis

1995 • 161 citations

Molecular Cloning of a Novel Putative G Protein-Coupled Receptor Expressed in the Cardiovascular System

1993 • 150 citations

Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate

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Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends

1997 • 142 citations

[21] Progressive alignment of amino acid sequences and construction of phylogenetic trees from them

1996 • 127 citations

Edg-2/Vzg-1 Couples to the Yeast Pheromone Response Pathway Selectively in Response to Lysophosphatidic Acid

1998 • 118 citations

Lysophosphatidic Acid Stimulates the G-protein-coupled Receptor EDG-1 as a Low Affinity Agonist

1998 • 116 citations

Signalling properties of lysophosphatidic acid

1993 • 112 citations

Cloning and Characterization of a Putative G-Protein Coupled Receptor Potentially Involved in Development

1994 • 110 citations

Molecular Cloning of the Novel Human G Protein-Coupled Receptor (GPCR) Gene Mapped on Chromosome 9

1996 • 106 citations

Isolation and expression of a mouse CB1 cannabinoid receptor gene

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Isolated rat cortical progenitor cells are maintained in division in vitro by membrane-associated factors

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Scanning and transmission electron microscope studies of interkinetic nuclear migration in the cerebral vesicles of the rat

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Human platelet aggregation induced by 1-alkyl-lysophosphatidic acid and its analogs: A new group of phospholipid mediators?

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Lysophospholipid Receptors: Implications for Neural Signaling

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Biochemical Characterization of the Interaction of Lipid Phosphoric Acids with Human Platelets: Comparison with Platelet Activating Factor

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Lysophosphatidic Acid Stimulates Neurotransmitter-Like Conductance Changes that Precede GABA and l-Glutamate in Early, Presumptive Cortical Neuroblasts

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Lysophosphatidic acid: A bioactive phospholipid with growth factor-like properties

1992 • 75 citations

The Mouse Gene for the Inducible G-Protein-Coupled Receptoredg-1

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Clonal Cell Lines Produced by Infection of Neocortical Neuroblasts Using Multiple Oncogenes Transduced by Retroviruses

1996 • 68 citations

Complete cDNA Sequence, Genomic Structure, and Chromosomal Localization of the LPA Receptor Gene,lpA1/vzg-1/Gpcr26

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Stimulatory effect of lysophosphatidic acids on uterine smooth muscles of non-pregant rats.

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Endogenous cannabinoid ligands — chemical and biological studies

1996 • 56 citations

Identification, Chromosomal Location, and Genome Organization of Mammalian G-Protein-Coupled Receptors

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Characterization of a Receptor Subtype-Selective Lysophosphatidic Acid Mimetic

1998 • 52 citations

Png-1, a nervous system-specific zinc finger gene, identifies regions containing postmitotic neurons during mammalian embryonic development

1997 • 47 citations

Cloning and characterization of a new member of the G-protein coupled receptor EDG family.

1995 • 41 citations

Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain

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Cloning of the rat edg-1 immediate-early gene: expression pattern suggests diverse functions

1994 • 27 citations

Characterization of edg-2, a human homologue of theXenopus maternal transcript G10 from endothelial cells

1995 • 24 citations

Maternally derived immunoglobulin light chain is present in the fetal mammalian CNS.

1997 • 23 citations

Maternally Derived Immunoglobulin Light Chain Is Present in the Fetal Mammalian CNS

1997 • 21 citations

Identification of Neural Programmed Cell Death Through the Detection of DNA Fragmentation In Situ and by PCR

1997 • 16 citations

The immediate‐early gene product MAD‐3/EDG‐3/IκBα is an endogenous modulator of fibroblast growth factor‐1 (FGF‐1) dependent human endothelial cell growth

1997 • 8 citations