Rho Family GTPases and Neuronal Growth Cone Remodelling: Relationship between Increased Complexity Induced by Cdc42Hs, Rac1, and Acetylcholine and Collapse Induced by RhoA and Lysophosphatidic Acid

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

Proteins regulating Ras and its relatives

1993 • 1,930 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts

1995 • 1,033 citations

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.

1994 • 985 citations

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

1991 • 961 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

Neurotransmitters as growth regulatory signals: role of receptors and second messengers

1993 • 806 citations

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1985 • 738 citations

Neurotransmitter regulation of neuronal outgrowth, plasticity and survival

1989 • 733 citations

Neurotransmitter Synthesis by Neuroblastoma Clones

1972 • 695 citations

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

1994 • 617 citations

Turning of nerve growth cones induced by neurotransmitters

1994 • 583 citations

Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase

1984 • 567 citations

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.

1990 • 560 citations

Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.

1994 • 469 citations

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

1985 • 458 citations

Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines

1996 • 454 citations

Disoriented pathfinding by pioneer neurone growth cones deprived of filopodia by cytochalasin treatment

1986 • 378 citations

The role of microtubule dynamics in growth cone motility and axonal growth.

1995 • 362 citations

Asymmetric modulation of cytosolic cAMP activity induces growth cone turning

1992 • 355 citations

Navigational errors made by growth cones without filopodia in the embryonic xenopus brain

1993 • 264 citations

Rho family GTPases: the cytoskeleton and beyond

1996 • 262 citations

A sensory role for neuronal growth cone filopodia

1993 • 223 citations

Rac mediates growth factor-induced arachidonic acid release

1995 • 207 citations

Analysis of microspike movements on the neuronal growth cone

1985 • 205 citations

Lysophosphatidic Acid‐Induced Neurite Retraction in PC12 Cells: Control by Phosphoinositide‐Ca²⁺ Signaling and Rho

1996 • 198 citations

Axon guidance molecules

1995 • 193 citations

ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons

1989 • 192 citations

Cytoskeletal events in growth cone steering

1994 • 182 citations

The Nerve Growth Cone

1991 • 142 citations

Growth cone configuration and advance: a time-lapse study using video- enhanced differential interference contrast microscopy

1988 • 128 citations

ADP-ribosylation of the proteins induces growth inhibition, neurite outgrowth and acetylcholine esterase in cultured PC-12 cells

1990 • 126 citations

The sensory-motor role of growth cone filopodia

1995 • 124 citations

Cell polarity in yeast

1994 • 114 citations

Differential receptor occupancy requirements for muscarinic cholinergic stimulation of inositol lipid hydrolysis in brain and in neuroblastomas.

1987 • 105 citations

Differing structural requirements for GTPase-activating protein responsiveness and NADPH oxidase activation by Rac.

1994 • 93 citations

Increased Neurite Outgrowth Induced by Inhibition of Protein Tyrosine Kinase Activity in PC12 Pheochromocytoma Cells

1993 • 55 citations

Breakpoint cluster region gene product-related domain of n-chimaerin. Discrimination between Rac-binding and GTPase-activating residues by mutational analysis

1994 • 52 citations

Growth Factor‐Like Effects Mediated by Muscarinic Receptors in PC12M1 Cells

1992 • 51 citations

The product of rab2, a small GTP binding protein, increases neuronal adhesion, and neurite growth in vitro

1990 • 49 citations

Growth cones: The mechanism of neurite advance

1991 • 44 citations

The dance of the growth cones — where to next?

1995 • 26 citations

Growth cone motility

1991 • 22 citations

The dance of the growth cones -- where to next?

1995 • 22 citations

Dynamic mechanisms of neuronal outgrowth

1994 • 19 citations

Measurement of changes in functional muscarinic acetylcholine receptor density in single neuroblastoma cells using calcium release kinetics

1994 • 11 citations

Acute neurite retraction triggered by lysophosphatidic acid: timing of the inhibitory effects of genistein

1994 • 10 citations