The role of nitric oxide and NMDA receptors in the development of motor neuron dendrites.

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

Dendritic organization in the neurons of the visual and motor cortices of the cat.

1953 • 2,180 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

1996 • 1,589 citations

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,458 citations

Developmental mechanisms that generate precise patterns of neuronal connectivity

1993 • 1,435 citations

Impaired Spatial Learning in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,336 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

Targeted disruption of the neuronal nitric oxide synthase gene

1993 • 1,300 citations

A Requirement for the Intercellular Messenger Nitric Oxide in Long-Term Potentiation

1991 • 1,136 citations

Blockade of "NMDA" Receptors Disrupts Experience-Dependent Plasticity of Kitten Striate Cortex

1987 • 920 citations

Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum

1991 • 875 citations

Activity-Dependent Action Potential Invasion and Calcium Influx into Hippocampal CA1 Dendrites

1995 • 846 citations

Impulse activity and the patterning of connections during cns development

1990 • 770 citations

Patterned Activity, Synaptic Convergence, and the NMDA Receptor in Developing Visual Pathways

1990 • 765 citations

A critical period for long-term potentiation at thalamocortical synapses

1995 • 702 citations

Potentiation of synaptic transmission in the hippocampus by phorbol esters

1986 • 647 citations

Experience-dependent modification of synaptic plasticity in visual cortex

1996 • 617 citations

PKCγ mutant mice exhibit mild deficits in spatial and contextual learning

1993 • 532 citations

N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes.

1987 • 529 citations

Modified hippocampal long-term potentiation in PKCγ-mutant mice

1993 • 507 citations

Disruption of experience-dependent synaptic modifications in striate cortex by infusion of an NMDA receptor antagonist

1990 • 497 citations

Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells

1995 • 484 citations

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

1997 • 481 citations

The role of nitric oxide in hippocampal long-term potentiation

1992 • 470 citations

Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience

1995 • 428 citations

Endothelial NOS and the Blockade of LTP by NOS Inhibitors in Mice Lacking Neuronal NOS

1994 • 422 citations

The role of dendrites in auditory coincidence detection

1998 • 389 citations

Stabilization of Dendritic Arbor Structure in Vivo by CaMKII

1998 • 381 citations

Participation of Postsynaptic PKC in Cerebellar Long-Term Depression in Culture

1991 • 340 citations

Altered synaptic plasticity and memory formation in nitric oxide synthase inhibitor-treated rats.

1993 • 340 citations

N-methyl-D-aspartate receptor antagonists disrupt the formation of a mammalian neural map.

1992 • 331 citations

Cloning and Characterization of Postsynaptic Density 93, a Nitric Oxide Synthase Interacting Protein

1996 • 327 citations

Neuronal growth cone collapse and inhibition of protein fatty acylation by nitric oxide

1993 • 327 citations

A Role for Endothelial NO Synthase in LTP Revealed by Adenovirus-Mediated Inhibition and Rescue

1996 • 304 citations

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.

1988 • 302 citations

Disruption of retinogeniculate afferent segregation by antagonists to NMDA receptors

1991 • 276 citations

Formation of olfactory memories mediated by nitric oxide

1997 • 266 citations

The Acquisition of Motor Behavior in Vertebrates

1996 • 259 citations

Nitric Oxide Regulates Cell Proliferation during Drosophila Development

1996 • 255 citations

Electrical activity in cerebellar cultures determines Purkinje cell dendritic growth patterns

1991 • 239 citations

Nitric oxide mediates the formation of synaptic connections in developing and regenerating olfactory receptor neurons

1994 • 238 citations

Involvement of Nitric Oxide in the Elimination of a Transient Retinotectal Projection in Development

1994 • 231 citations

Nitric Oxide and Cyclic GMP Regulate Retinal Patterning in the Optic Lobe of Drosophila

1998 • 224 citations

Postsynaptic Inhibitors of Calcium/Calmodulin-Dependent Protein Kinase Type II Block Induction But Not Maintenance of Pairing-Induced Long-Term Potentiation

1997 • 217 citations

Sustained increase in intracellular calcium promotes neuronal survival

1991 • 213 citations

NMDA receptor agonist and antagonists alter retinal ganglion cell arbor structure in the developing frog retinotectal projection

1990 • 196 citations

Abnormal Hippocampal Spatial Representations in αCaMKII ^T286A and CREB ^αΔ− Mice

1998 • 186 citations

Regulation of motor neuron dendrite growth by NMDA receptor activation

1994 • 179 citations

The relation of postsynaptic geometry to the number of presynaptic axons that innervate autonomic ganglion cells

1981 • 172 citations

Nitric oxide mediates activity-dependent synaptic suppression at developing neuromuscular synapses

1995 • 171 citations

Are Adult Learning Mechanisms Also Used for Development?

1992 • 171 citations

Nitric Oxide-Dependent Production of cGMP Supports the Survival of Rat Embryonic Motor Neurons Cultured with Brain-Derived Neurotrophic Factor

1998 • 170 citations

N-methyl-D-aspartate receptors are transiently expressed in the developing spinal cord ventral horn.

1992 • 169 citations

Immediate and long-lasting effects of MK-801 on motor activity, spatial navigation in a swimming pool and EEG in the rat

1989 • 159 citations

Evidence that nerve growth factor dependence of sympathetic neurons for survival in vitro may be determined by levels of cytoplasmic free Ca2+.

1991 • 159 citations

Spontaneous Ca2+ spikes and waves in embryonic neurons: signaling systems for differentiation

1994 • 144 citations

Quantitative and qualitative changes in AMPA receptor expression during spinal cord development

1995 • 140 citations

A Role for Nitric Oxide in the Development of the Ferret Retinogeniculate Projection

1996 • 132 citations

Anterograde Signaling by Nitric Oxide: Characterization andIn VitroReconstitution of an Identified Nitrergic Synapse

1998 • 132 citations

Do NMDA receptors have a critical function in visual cortical plasticity?

1993 • 131 citations

Distinct spatiotemporal distributions of the N‐Methyl‐<scp>D</scp>‐aspartate receptor channel subunit mRNAs in the mouse cervical cord

1994 • 128 citations

The selective neuronal NO synthase inhibitor 7-nitro-indazole blocks both long-term potentiation and depotentiation of field EPSPs in rat hippocampal CA1 in vivo

1996 • 124 citations

Enhancement of transmission at the developing retinogeniculate synapse

1993 • 113 citations

Molecular evidence for nitric oxide-mediated motor neuron development

1993 • 111 citations

Enhancement of long-term potentiation by cis-unsaturated fatty acid: relation to protein kinase C and phospholipase A2

1987 • 108 citations

Isolation of embryonic chick motoneurons and their survival in vitro

1986 • 107 citations

In situ hybridization analysis of AMPA receptor subunit gene expression in the developing rat spinal cord

1995 • 106 citations

The critical period for long-term potentiation in primary sensory cortex

1995 • 92 citations

Induction of a Neuronal Proteoglycan by the NMDA Receptor in the Developing Spinal Cord

1990 • 91 citations

Morphology of developing rat genioglossal motoneurons studied in vitro: Changes in length, branching pattern, and spatial distribution of dendrites

1994 • 90 citations

Geometry of neonatal neurones and the regulation of synapse elimination

1981 • 90 citations

Dendritic development and preferential growth into synaptogenic fields: A quantitative study of Golgi‐impregnated spinal motor neurons

1988 • 84 citations

Exogenous nitric oxide causes collapse of retinal ganglion cell axonal growth conesin vitro

1996 • 81 citations

Reduced cortical inhibitory synaptogenesis in organotypic cerebellar cultures developing in the absence of neuronal activity

1994 • 77 citations

Motor Development in Early and Later Childhood

1993 • 74 citations

Long-term potentiation and depression in the ventral horn of rat spinal cord in vitro

1993 • 71 citations

Postnatal maturation of the dendritic fields of motoneuron pools supplying flexor and extensor muscles of the distal forelimb in the rat

1993 • 46 citations

Inhibition of nitric oxide synthase does not prevent ocular dominance plasticity in kitten visual cortex.

1996 • 44 citations

Analysis of synaptic distribution within single retinal axonal arbors after chronic NMDA treatment

1995 • 38 citations

Fine-structural alterations and clustering of developing synapses after chronic treatments with low levels of NMDA

1993 • 37 citations

Inhibition of nitric oxide synthase does not alter ocular dominance shifts in kitten visual cortex.

1996 • 33 citations

The Effects of Neonatal Dorsal Root Section on the Survival and Dendritic Development of Lumbar Motoneurons in the Rat

1996 • 19 citations