Expression of lysophosphatidic acid receptor in rat astrocytes: mitogenic effect and expression of neurotrophic genes.

Rat hippocampal neurons in dispersed cell culture

1977 • 1,106 citations

Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

1989 • 846 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex.

1996 • 727 citations

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

1989 • 692 citations

Trophic Interactions Between Astroglial Cells and Hippocampal Neurons in Culture

1980 • 672 citations

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

1994 • 617 citations

Arachidonic Acid Cascade and Signal Transduction

1990 • 597 citations

One-hour downward alkaline capillary transfer for blotting of DNA and RNA

1992 • 551 citations

Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid

1999 • 517 citations

Lysophosphatidic acid: G-protein signalling and cellular responses

1997 • 492 citations

Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.

1983 • 446 citations

Deficient Cerebellar Long-Term Depression, Impaired Eyeblink Conditioning, and Normal Motor Coordination in GFAP Mutant Mice

1996 • 392 citations

Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells.

1992 • 355 citations

Rat β‐nerve growth factor sequence and site of synthesis in the adult hippocampus

1988 • 309 citations

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes

1989 • 254 citations

Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid

1999 • 253 citations

Interleukin-6 as a neurotrophic factor for promoting the survival of cultured basal forebrain cholinergic neurons from postnatal rats

1989 • 252 citations

Molecular Cloning of the Human Edg2 Protein and Its Identification as a Functional Cellular Receptor for Lysophosphatidic Acid

1997 • 232 citations

Lysophosphatidic acid signalling

1995 • 223 citations

Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action.

1993 • 210 citations

Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid.

1992 • 199 citations

Interleukin 3 as a trophic factor for central cholinergic neurons in vitro and in vivo

1990 • 184 citations

Lysophosphatidic acid receptor genevzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain

1998 • 180 citations

Astrocytes of the brain synthesize interleukin 3-like factors.

1985 • 177 citations

Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes

1996 • 173 citations

Lysophosphatidic Acid Increases Tight Junction Permeability in Cultured Brain Endothelial Cells

1997 • 172 citations

A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs)

1999 • 153 citations

Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator

1994 • 152 citations

The influence of long-term potentiation on the spatial relationship between astrocyte processes and potentiated synapses in the dentate gyrus neuropil of rat brain

1991 • 147 citations

Lysophosphatidic acid alters cerebrovascular reactivity in piglets

1995 • 120 citations

Thrombin Receptor Activation Stimulates Astrocyte Proliferation and Reversal of Stellation by Distinct Pathways: Involvement of Tyrosine Phosphorylation

1995 • 119 citations

Predominant Expression of Platelet-Activating Factor Receptor in the Rat Brain Microglia

1996 • 109 citations

Growth factor-like phospholipids generated after corneal injury

1998 • 107 citations

Lysophosphatidic Acid Induces Necrosis and Apoptosis in Hippocampal Neurons

1998 • 98 citations

Platelet-activating factor and polyunsaturated fatty acids in cerebral ischemia or convulsions: Intracellular PAF-binding sites and activation of a fos/jun/AP-1 transcriptional signaling system

1991 • 97 citations

Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes

1994 • 87 citations

Lysophospholipid Receptors: Implications for Neural Signaling

1999 • 83 citations

Quantification, characterization and fatty acid composition of lysophosphatidic acid in different rat tissues

1989 • 83 citations

Lysophosphatidic acid-mediated signal-transduction pathways involved in the induction of the early-response genes prostaglandin G/H synthase-2 and Egr-1: a critical role for the mitogen-activated protein kinase p38 and for Rho proteins

1998 • 71 citations

Identification and characterization of a lysophosphatidic acid receptor.

1994 • 64 citations

Purification of a phosphatidic-acid-hydrolysing phospholipase A2 from rat brain

1995 • 62 citations

Lysophosphatidic acid stimulates actomyosin contraction in astrocytes

1998 • 57 citations

Lysophosphatidic Acid Decreases Glutamate and Glucose Uptake by Astrocytes

1996 • 45 citations

Control of astrocyte volume by intracellular and extracellular Ca²⁺

1990 • 39 citations

Purification of a lysophosphatidic acid-hydrolysing lysophospholipase from rat brain

1994 • 36 citations

Endothelin Receptors on Cultured Fetal Rat Diencephalic Glia

1992 • 30 citations

The effect of active serum albumin on PC12 cells: II. Intracellular Ca2+ transients and their role in neurite retraction

1992 • 26 citations

Lysophosphatidic acid depletes intracellular calcium stores different from those mediating capacitative calcium entry in C6 rat glioma cells

1997 • 14 citations