The importin β/importin 7 heterodimer is a functional nuclear import receptor for histone H1

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

1997 • 2,062 citations

A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

1997 • 1,221 citations

NUCLEOCYTOPLASMIC TRANSPORT: The Soluble Phase

1998 • 1,184 citations

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex.

1996 • 1,161 citations

Chromatin Structure and Function

1979 • 1,050 citations

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.

1990 • 909 citations

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

1995 • 767 citations

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1993 • 760 citations

Isolation of a protein that is essential for the first step of nuclear protein import

1994 • 710 citations

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1991 • 703 citations

A Novel Receptor-Mediated Nuclear Protein Import Pathway

1996 • 669 citations

Identification of different roles for RanGDP and RanGTP in nuclear protein import.

1996 • 644 citations

The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus

1997 • 628 citations

Export of Importin α from the Nucleus Is Mediated by a Specific Nuclear Transport Factor

1997 • 613 citations

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

1993 • 544 citations

RanGAP1 induces GTPase activity of nuclear Ras-related Ran.

1994 • 526 citations

Importin beta , transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells

1998 • 524 citations

The Cell Nucleus

1966 • 522 citations

Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

1995 • 511 citations

Movement of a karyophilic protein through the nuclear pores of oocytes.

1984 • 510 citations

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

1997 • 480 citations

Distinct functions for the two importin subunits in nuclear protein import

1995 • 479 citations

NTF2 mediates nuclear import of Ran

1998 • 459 citations

Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.

1995 • 430 citations

A Novel Class of RanGTP Binding Proteins

1997 • 427 citations

A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus.

1996 • 419 citations

Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62.

1995 • 385 citations

Identification of a tRNA-Specific Nuclear Export Receptor

1998 • 379 citations

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA.

1989 • 367 citations

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex

1997 • 365 citations

A Distinct Nuclear Import Pathway Used by Ribosomal Proteins

1997 • 335 citations

Transport into and out of the cell nucleus

1998 • 332 citations

Purification of a Ran-interacting protein that is required for protein import into the nucleus.

1994 • 318 citations

Roles of H1 domains in determining higher order chromatin structure and H1 location

1986 • 310 citations

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope.

1994 • 306 citations

Identification of a nuclear export receptor for tRNA

1998 • 286 citations

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide.

1991 • 281 citations

Facilitated nuclear transport of histone H1 and other small nucleophilic proteins

1990 • 278 citations

Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure

1998 • 276 citations

Sequence and characterization of cytoplasmic nuclear protein import factor p97.

1995 • 274 citations

Transportin-mediated Nuclear Import of Heterogeneous Nuclear RNP Proteins

1997 • 252 citations

The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import.

1996 • 252 citations

RanBP1 is crucial for the release of RanGTP from importin β‐related nuclear transport factors

1997 • 250 citations

An Asymmetric Model for the Nucleosome: A Binding Site for Linker Histones Inside the DNA Gyres

1996 • 233 citations

Cloning of two novel human importin‐α subunits and analysis of the expression pattern of the importin‐α protein family

1997 • 230 citations

Transport of macromolecules between the nucleus and the cytoplasm.

1998 • 207 citations

tRNA transport from the nucleus in a eukaryotic cell: carrier-mediated translocation process.

1983 • 202 citations

Importin Provides a Link between Nuclear Protein Import and U snRNA Export

1996 • 189 citations

Chromatin structure and function

1994 • 180 citations

Cloning and Characterization of SRP1, a Suppressor of Temperature-Sensitive RNA Polymerase I Mutations, in Saccharomyces cerevisiae

1992 • 175 citations

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import.

1996 • 175 citations

Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis

1999 • 167 citations

Yrb4p, a yeast Ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus

1997 • 163 citations

The nuclear pore‐targeting complex binds to nuclear pores after association with a karyophile

1995 • 163 citations

Ran-unassisted Nuclear Migration of a 97-kD Component of Nuclear Pore–targeting Complex

1997 • 160 citations

The yeast nuclear import receptor is required for mitosis.

1995 • 153 citations

Disassembly of RanGTP-Karyopherin β Complex, an Intermediate in Nuclear Protein Import

1997 • 147 citations

Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-β

1997 • 146 citations

A Karyophilic Protein Forms a Stable Complex with Cytoplasmic Components Prior to Nuclear Pore Binding

1995 • 144 citations

Nuclear import of U snRNPs requires importin beta

1997 • 141 citations

The translocation of transportin–cargo complexes through nuclear pores is independent of both Ran and energy

1999 • 138 citations

Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities.

1996 • 137 citations

Ran-binding Protein 1 (RanBP1) Forms a Ternary Complex with Ran and Karyopherin β and Reduces Ran GTPase-activating Protein (RanGAP) Inhibition by Karyopherin β

1997 • 134 citations

Identification of novel homologues of mouse importin α, the α subunit of the nuclear pore‐targeting complex, and their tissue‐specific expression

1997 • 129 citations

Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p.

1994 • 125 citations

Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis

1998 • 113 citations

Cloning and characterization of hSRP1γ, a tissue-specific nuclear transport factor

1998 • 108 citations

Ran-dependent Signal-mediated Nuclear Import Does Not Require GTP Hydrolysis by Ran

1998 • 108 citations

Cloning and characterization of SRP1, a suppressor of temperature-sensitive RNA polymerase I mutations, in Saccharomyces cerevisiae.

1992 • 95 citations

Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear pore.

1997 • 87 citations

Organization and expression of H1 histone and H1 replacement histone genes

1994 • 86 citations

Functions of the GTPase Ran in RNA export from the nucleus

1998 • 80 citations

The Histone H1° Contains Multiple Sequence Elements for Nuclear Targeting

1998 • 31 citations

Heterologous expression of human H1 histones in yeast

1998 • 25 citations

Nuclear transport of H1 histones meets the criteria of a nuclear localization signal—mediated process

1997 • 24 citations

Nuclear transport of H1 histones meets the criteria of a nuclear localization signal—mediated process

1997 • 3 citations