Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

The ras protein family: evolutionary tree and role of conserved amino acids

1991 • 573 citations

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA.

1989 • 367 citations

Characterization of Four Novel ras-Like Genes Expressed in a Human Teratocarcinoma Cell Line

1990 • 285 citations

Premature chromosome condensation in a ts DNA-mutant of BHK cells

1978 • 260 citations

A Cytosolic Protein Catalyzes the Release of GDP from p21 ^ras

1990 • 231 citations

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase

1991 • 231 citations

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

1987 • 208 citations

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.

1990 • 202 citations

Biochemical properties of Ha-ras encoded p21 mutants and mechanism of the autophosphorylation reaction.

1988 • 196 citations

Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis.

1991 • 195 citations

Enhancement of the GDP-GTP Exchange of RAS Proteins by the Carboxyl-Terminal Domain of SCD25

1990 • 152 citations

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

1990 • 152 citations

A novel membrane factor stimulates guanine nucleotide exchange reaction of ras proteins

1990 • 119 citations

Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants.

1989 • 98 citations

A 47-kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation.

1990 • 95 citations

The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1.

1991 • 76 citations

Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation.

1986 • 68 citations

Small GTP-binding proteins of the ras family: a conserved functional mechanism?

1991 • 65 citations

Cloning of Xenopus RCC1 cDNA, a Homolog of the Human RCC1 Gene: Complementation of tsBN2 Mutation and Identification of the Product1

1990 • 34 citations