Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

Nuclei from Rat Liver: Isolation Method That Combines Purity with High Yield

1966 • 1,687 citations

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.

1990 • 909 citations

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1993 • 760 citations

Identification and characterization of a nuclear pore complex protein

1986 • 610 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

1993 • 544 citations

Movement of a karyophilic protein through the nuclear pores of oocytes.

1984 • 510 citations

Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

1991 • 391 citations

Purification of a Ran-interacting protein that is required for protein import into the nucleus.

1994 • 318 citations

A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm

1993 • 308 citations

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope.

1994 • 306 citations

Internal protein sequence analysis: Enzymatic digestion for less than 10 μg of protein bound to polyvinylidene difluoride or nitrocellulose membranes

1992 • 290 citations

Pores for thought: nuclear pore complex proteins

1994 • 286 citations

The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors

1992 • 278 citations

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

1993 • 261 citations

The human CAN protein, a putative oncogene productassociated with myeloid leukemogenesis, is a nuclear pore complex protein thatfaces the cytoplasm.

1994 • 238 citations

Structure and Function of the Nuclear Pore Complex

1992 • 237 citations

Interactions and three-dimensional localization of a group of nuclear pore complex proteins.

1994 • 206 citations

A G protein involved in nucleocytoplasmic transport: the role of Ran

1994 • 159 citations

Intranuclear filaments containing a nuclear pore complex protein.

1993 • 131 citations

Nup155 is a novel nuclear pore complex protein that contains neither repetitive sequence motifs nor reacts with WGA.

1993 • 89 citations