Stromal regulation of epithelial function

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Transforming growth factor beta

2011 • 1,990 citations

Glycosphingolipids in Cellular Interaction, Differentiation, and Oncogenesis

1981 • 1,650 citations

The cadherins: cell-cell adhesion molecules controlling animal morphogenesis

1988 • 1,626 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

1987 • 1,333 citations

Epithelial-Mesenchymal Interactions

1967 • 1,218 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

Cell biology of extracellular matrix

1992 • 1,042 citations

Cloning of Human Androgen Receptor Complementary DNA and Localization to the X Chromosome

1988 • 1,007 citations

Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

1986 • 989 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Mesoderm induction in early Xenopus embryos by heparin-binding growth factors

1987 • 953 citations

Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo

1987 • 883 citations

The Role of Extracellular Matrix in Development

1985 • 867 citations

Cell Surface Receptors for Extracellular Matrix Molecules

1987 • 793 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

BIOCHEMICAL INTERACTIONS OF TUMOR CELLS WITH THE BASEMENT MEMBRANE

1986 • 693 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Cell Adhesion Molecules in the Regulation of Animal Form and Tissue Pattern

1986 • 630 citations

X-linked Gene for Testicular Feminization in the Mouse

1970 • 551 citations

Changes in integrin receptors on oncogenically transformed cells

1989 • 548 citations

Normal and abnormal aspects of proteinuria

1986 • 536 citations

Origin and evolution of benign prostatic enlargement.

1978 • 530 citations

Spheroidal aggregate culture of rat liver cells: histotypic reorganization, biomatrix deposition, and maintenance of functional activities.

1985 • 508 citations

Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice.

1986 • 506 citations

Cell adhesion protein receptors as targets for transforming growth factor-$beta; action

1987 • 498 citations

Polyoma virus transforming protein associates with the product of the c-src cellular gene

1983 • 497 citations

Morphoregulatory molecules

1988 • 460 citations

Mesoderm Induction in Amphibians: the Role of TGF-β2-Like Factors

1988 • 452 citations

Cell and tissue interactions

1977 • 449 citations

Hormone-Induced Morphogenesis and Growth: Role of Mesenchymal–Epithelial Interactions

1983 • 441 citations

The Influence of Extracellular Matrix on Gene Expression: Is Structure The Message?

1987 • 437 citations

Morphogenesis of Ductal Networks in the Mouse Prostate1

1986 • 406 citations

The cell surface in animal embryogenesis and development

1977 • 389 citations

THE MAMMALIAN URINARY BLADDERAN ACCOMMODATING ORGAN

1975 • 389 citations

Embryonic induction - molecular prospects

1987 • 381 citations

Regulation of epidermal growth factor receptor by estrogen.

1985 • 379 citations

The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.

1990 • 375 citations

Long-term effects on the female mouse genital tract associated with prenatal exposure to diethylstilbestrol.

1980 • 364 citations

Mesenchyme-Dependent Morphogenesis and Epithelium-Specific Cytodifferentiation in Mouse Mammary Gland

1976 • 348 citations

Mechanisms of organogenetic tissue interaction.

1967 • 343 citations

Domains of laminin with growth-factor activity

1989 • 341 citations

The Role of extracellular matrix in development

1984 • 334 citations

Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation

1984 • 333 citations

Early pancreas organogenesis: Morphogenesis, tissue interactions, and mass effects

1967 • 326 citations

Stromal-epithelial interactions in adult organs

1985 • 315 citations

Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture.

1984 • 315 citations

The Human Laminin Receptor Is a Member of the Integrin Family of Cell Adhesion Receptors

1988 • 310 citations

Morphogenesis of skin

1976 • 309 citations

DEPENDENCE OF SALIVARY EPITHELIAL MORPHOLOGY AND BRANCHING MORPHOGENESIS UPON ACID MUCOPOLYSACCHARIDE-PROTEIN (PROTEOGLYCAN) AT THE EPITHELIAL SURFACE

1972 • 304 citations

The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wild‐type and androgen‐insensitive (Tfm) Mice

1978 • 304 citations

Intrinsic and extrinsic regulation of the differentiation of skin, corneal and esophageal epithelial cells

1980 • 295 citations

Epithelial-mesenchymal interactions in prostatic development. I. morphological observations of prostatic induction by urogenital sinus mesenchyme in epithelium of the adult rodent urinary bladder.

1983 • 289 citations

Epithelial-mesenchymal interactions in development

1983 • 287 citations

Mammalian lung development: Interactions in formation and morphogenesis of tracheal buds

1970 • 284 citations

Formation of basement membranes in the embryonic kidney: an immunohistological study

1981 • 280 citations

Morphogenesis and Pattern Formation

1981 • 277 citations

Influence of Estrogens on Mouse Uterine Epidermal Growth Factor Precursor Protein and Messenger Ribonucleic Acid

1988 • 273 citations

Transforming growth factor-β: Multiple effects on cell differentiation and extracellular matrices

1988 • 271 citations

Induction in vitro of tracheal buds by pulmonary mesenchyme grafted on tracheal epithelium

1962 • 251 citations

Tissue interaction in androgen response of embryonic mammary rudiment of mouse: identification of target tissue for testosterone.

1976 • 250 citations

The prostate gland : morphology and pathobiology

1988 • 246 citations

Ductal morphogenesis in the mouse mammary gland: Evidence supporting a role for epidermal growth factor

1988 • 232 citations

Stromal induction and specification of morphogenesis and cytodifferentiation of the epithelia of the mullerian ducts and urogenital sinus during development of the uterus and vagina in mice

1976 • 231 citations

Epithelial-Stromal Interactions in Development of the Urogenital Tract

1976 • 231 citations

Stromal-epithelial interactions—I. Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice

1981 • 227 citations

Stromal-Epithelial Interactions in Sex Differentiation

1980 • 217 citations

Epithelio‐mesenchymal specificity in the morphogenesis of mouse sub‐mandibular rudiments in vitro

1953 • 216 citations

Lung Maturation in the Fetal Rat: Acceleration by Injection of Fibroblast-Pneumonocyte Factor

1979 • 213 citations

Colonic pericryptal fibroblast sheath: replication, migration, and cytodifferentiation of a mesenchymal cell system in adult tissue. I. Autoradiographic studies of normal rabbit colon.

1968 • 211 citations

Developmental and Evolutionary Aspects of the Neural Crest

1988 • 196 citations

Regulation of specific protein synthesis in cytodifferentiation

1968 • 191 citations

PROSTATE CANCER IN THE RAT.

1963 • 187 citations

Mesenchyme-Dependent Differentiation of Epithelial Progenitor Cells in the Gut

1987 • 182 citations

Part II. Androgen Metabolism and Mechanism of Action in Male Pseudohermaphroditism: A Study of Testicular Feminization

1973 • 180 citations

STRUCTURAL FEATURES OF THE EPITHELIO-MESENCHYMAL INTERFACE OF RAT DUODENAL MUCOSA DURING DEVELOPMENT

1972 • 171 citations

The Induction of Hair Follicles by Embryonic Dermal Papillae**From the Department of Anatomy, The Univerity of Chicago, ChiCago, Illinois 60637.

1970 • 171 citations

Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization

1972 • 156 citations

Proliferation of Mouse Uterine Epithelial Cellsin Vitro

1986 • 156 citations

Colonic pericryptal fibroblast sheath: replication, migration, and cytodifferentiation of a mesenchymal cell system in adult tissue. II. Fine structural aspects of normal rabbit and human colon.

1968 • 155 citations

Cellular interactions promote tissue-specific function, biomatrix deposition and junctional communication of primary cultured hepatocytes

1988 • 148 citations

Estrogen Stimulation of Deoxyribonucleic Acid Synthesis in Uterine Epithelial Cells which Lack Estrogen Receptors*

1986 • 148 citations

Normal development of the prostate and seminal vesicles of the rat with a study of experimental postnatal modifications

1936 • 147 citations

Aspects of synthesis and order in growth

1954 • 147 citations

Antibodies to cell surface ganglioside GD3 perturb inductive epithelial-mesenchymal interactions

1988 • 142 citations

Sex differences in fetal lung maturation.

1981 • 141 citations

Colonic Pericryptal Fibroblast Sheath: Replication, Migration, and Cytodifferentiation of a Mesenchymal Cell System in Adult Tissue

1968 • 141 citations

Cytological Basis for Permanent Vaginal Changes in Mice Treated Neonatally with Steroid Hormones

1976 • 139 citations

Nerve growth factor enhances expression of neuron-glia cell adhesion molecule in PC12 cells.

1986 • 139 citations

Estrogens in the Environment II: Influences on Development

1987 • 136 citations

Purification of a paracrine factor, P-Mod-S, produced by testicular peritubular cells that modulates Sertoli cell function.

1988 • 134 citations

Experimental intersexuality. The effects of estrogens on the antenatal sexual development of the rat

1940 • 134 citations

Cell Interactions in Differentiation

1977 • 131 citations

Intimate cell contacts at the epithelial/mesenchymal interface in embryonic mouse lung

1976 • 131 citations

The effect of androgen deprivation on branching morphogenesis in the mouse prostate

1988 • 131 citations

Breast Cancer: Induction of Differentiation by Embryonic Tissue

1973 • 130 citations

Linoleate metabolites enhance the in vitro proliferative response of mouse mammary epithelial cells to epidermal growth factor.

1987 • 129 citations

Colonic Pericryptal Fibroblast Sheath: Replication, Migration, and Cytodifferentiation of a Mesenchymal Cell System in Adult Tissue

1968 • 123 citations

The cell surface in animal embryogenesis and development

1976 • 119 citations

Glandular epithelial induction by embryonic mesenchyme in adult bladder epithelium of BALB/c mice.

1980 • 116 citations

Type I collagen reduces the degradation of basal lamina proteoglycan by mammary epithelial cells.

1981 • 114 citations

Stimulation of corneal differentiation by interaction between cell surface and extracellular matrix. I. Morphometric analysis of transfilter "induction".

1975 • 114 citations

Role of Uterine Epithelium in the Development of Myometrial Smooth Muscle Cells1

1989 • 113 citations

Tissue Interactions in Carcinogenesis

1973 • 113 citations

Intrauterine transplantation of rat basal cell carcinoma as a model for reconversion of malignant to benign growth.

1977 • 112 citations

Induction of supernumerary tracheal buds and the stimulation of DNA synthesis in the embryonic chick lung and trachea by epidermal growth factor

1980 • 111 citations

Induction of androgen receptor formation by epithelium-mesenchyme interaction in embryonic mouse mammary gland.

1982 • 110 citations

Basement Membrane Formation in Transfilter Tooth Culture and Its Relation to Odontoblast Differentiation

1978 • 109 citations

Glucocorticoid-thyroid synergism in lung maturation: a mechanism involving epithelial-mesenchymal interaction.

1983 • 108 citations

A new in vivo model to study invasion and metastasis of human bladder carcinoma.

1987 • 107 citations

Persistence of responsiveness of adult mouse mammary gland to induction by embryonic mesenchyme

1979 • 106 citations

Regression of mouse mammary gland anlagen in recombinants of Tfm and wild-type tissues: testosterone acts via the mesenchyme

1977 • 105 citations

CONTROL OF SPECIFIC SYNTHESIS IN THE DEVELOPING PANCREAS.

1964 • 105 citations

Cellular controls in differentiation

1981 • 102 citations

Antibodies to liver cell adhesion molecule perturb inductive interactions and alter feather pattern and structure.

1986 • 99 citations

Glycosphingolipids as differentiation-dependent, tumor-associated markers and as regulators of cell proliferation

1984 • 98 citations

Growth of normal mouse vaginal epithelial cells in and on collagen gels.

1983 • 96 citations

Mammalian Cell Culture

1984 • 96 citations

PROSTATIC INDUCTION: INTERACTION OF EPITHELIUM AND MESENCHYME FROM NORMAL WILD-TYPE MICE AND ANDROGEN-INSENSITIVE MICE WITH TESTICULAR FEMINIZATION

1980 • 95 citations

Inductive Properties of Fibroblastic Cell Cultures Derived from Rat Intestinal Mucosa on Epithelial Differentiation

1982 • 92 citations

Epithelial-mesenchymal interactions in prostatic development. II. Biochemical observations of prostatic induction by urogenital sinus mesenchyme in epithelium of the adult rodent urinary bladder.

1983 • 91 citations

Local Embryonic Matrices Determine Region-Specific Phenotypes in Neural Crest Cells

1988 • 88 citations

Cytosol Androgen Binding in Submandibular Gland and Kidney of the Normal Mouse and the Mouse with Testicular Feminization

1976 • 87 citations

Developmental and evolutionary aspects of the neural crest

1987 • 86 citations

Androgenic induction of DNA synthesis in prostatic glands induced in the urothelium of testicular feminized (Tfm/Y) mice

1986 • 85 citations

Normal epithelial branching morphogenesis in the absence of collagen I

1986 • 84 citations

Age-Dependent Loss of Sensitivity of Female Urogenital Sinus to Androgenic Conditions as a Function of the Epithelial-Stromal Interaction in Mice

1975 • 83 citations

Tissue interactions in carcinogenesis

1972 • 83 citations

Effects of human breast fibroblasts on growth and 17β-estradiol dehydrogenase activity of MCF-7 cells in culture

1988 • 82 citations

Phosphoethanolamine as a growth factor of a mammary carcinoma cell line of rat.

1979 • 81 citations

Neural cell adhesion molecule regulates cell contact-mediated changes in choline acetyltransferase activity of embryonic chick sympathetic neurons

1988 • 81 citations

Identification of a non-mitogenic paracrine factor involved in mesenchymal-epithelial cell interactions between testicular peritubular cells and Sertoli cells

1986 • 81 citations

3T3-L1 Adipocytes promote the growth of mammary epithelium

1984 • 81 citations

An In Vitro Study of Hair and Vibrissae Development in Embryonic Mouse Skin**From the Department of Zoology, University of Chicago, Chicago, Illinois.

1966 • 79 citations

The functional integration of cells in animal tissues

1982 • 78 citations

Androgen stimulation of sertoli cell function is enhanced by peritubular cells

1985 • 78 citations

Stimulation of corneal differentiation by interaction between cell surface and extracellular matrix

1976 • 78 citations

Immunodetection of estrogen receptor in epithelial and stromal tissues of neonatal mouse uterus.

1988 • 77 citations

In vitro analysis of the hormonal basis for the sexual dimorphism in the embryonic development of the mouse mammary gland

1971 • 76 citations

Cell Culture Studies Using Extracts of Extracellular Matrix to Study Growth and Differentiation in Mammalian Cells

1984 • 74 citations

Autoradiographic localization of androgen binding in the developing mouse prostate

1983 • 74 citations

Loss of competence in amphibian induction can take place in single nondividing cells.

1989 • 73 citations

Development and characteristics of the available animal model systems for the study of prostatic cancer.

1987 • 72 citations

Immunohistochemical localization of ganglioside GD3 in human malignant melanoma, epithelial tumors, and normal tissues.

1985 • 71 citations

The Structure and Function of Steroid Receptor Protein

1989 • 70 citations

The induction of new ductal growth in adult prostatic epithelium in response to an embryonic prostatic inductor

1986 • 69 citations

Analysis of prostatic bud induction by brief androgen treatment in the fetal rat urogenital sinus

1986 • 69 citations

Induction of mesodermal tissues by acidic and basic heparin binding growth factors

1988 • 68 citations

Demonstration of cytoplasmic processes in Millipore filters permitting kidney tubule induction

1975 • 68 citations

Ontogeny of Mesenchymal Androgen Receptors in the Embryonic Mouse Mammary Gland

1983 • 66 citations

Binding of 125I-epidermal growth factor in human uterus

1986 • 65 citations

A modified immunohistochemical procedure for the detection of estrogen receptor in mouse tissues

1989 • 63 citations

Phospholipids containing polyunsaturated fatty acyl groups are mitogenic for normal mouse mammary epithelial cells in serum-free primary cell culture.

1989 • 62 citations

Neonatal Intensive Care

1977 • 61 citations

Autoradiographic Localization of Epidermal Growth Factor Receptors to All Major Uterine Cell Types1

1988 • 60 citations

Immunocytochemical Localization of Estrogen Receptors in the Macaque Endometrium during the Luteal-Follicular Transition*

1986 • 60 citations

Embryonic Inductive Tissues That Cause Histologic Differentiation of Murine Mammary Carcinoma In Vitro<xref ref-type="fn" rid="fn2">2</xref>

1975 • 58 citations

Proliferative effects of insulin and epidermal growth factor on mouse mammary epithelial cells in primary culture. Enhancement by hydroxyeicosatetraenoic acids and synergism with prostaglandin E2.

1988 • 57 citations

Avian scale development

1984 • 56 citations

The Induction of Adenocarcinomatous Differentiation in Neoplastic Bladder Epithelium by an Embryonic Prostatic Inductor

1982 • 55 citations

Regulation of functional cytodifferentiation and histogenesis in mammary epithelial cells: role of the extracellular matrix.

1989 • 55 citations

Autoradiographic analysis of nuclear estrogen binding sites during postnatal development of the genital tract of female mice

1982 • 53 citations

Androgen receptor in cultured interstitial cells derived from immature rat testis

1980 • 53 citations

Induction of functional cytodifferentiation in the epithelium of tissue recombinants : I. Homotypic seminal vesicle recombinants

1989 • 52 citations

Ultrastructural evidence of stromal/epithelial interactions in the human endometrial cycle

1988 • 51 citations

Cellular interactions in animal development

1975 • 51 citations

Dihydrotestosterone blocks fetal lung fibroblast-pneumonocyte factor at a pretranslational level.

1987 • 49 citations

Avian scale development

1992 • 45 citations

Characterization of Androgen Binding and Deoxyribonucleic Acid Synthesis in Prostate-Like Structures Induced in the Urothelium of Testicular Feminized (Tfm/Y) Mice 1

1984 • 45 citations

A method for studying epithelialmesenchymal interactions in human oral mucosal lesions

1979 • 44 citations

Directive versus permissive induction: a working hypothesis.

1977 • 44 citations

Role of the epithelial-stromal interaction during the development and expression of ovary-independent vaginal hyperplasia

1977 • 42 citations

The Sex Difference in Type II Cell Surfactant Synthesis Originates in the Fibroblast in Vitro

1984 • 41 citations

Localization of Androgen Target Cells in the Rat Testis: Autoradiographic Studies

1975 • 41 citations

Epithelial component of host-tumor interactions in the orthotopic site preference of a mouse mammary tumor.

1988 • 40 citations

Morphogenesis of mouse mammary epithelial cells growing within collagen gels: ultrastructural and immunocytochemical characterization

1988 • 39 citations

Induction of Mesoderm by a Viral Oncogene in Early Xenopus Embryos

1989 • 39 citations

Dihydrotestosterone inhibits fibroblast-pneumonocyte factor-mediated synthesis of saturated phosphatidylcholine by fetal rat lung cells

1985 • 39 citations

Influence of epithelio‐mesenchymal interactions on tumor induction by polyoma virus

1966 • 38 citations

Regional differences in the inductive activity of the mesenchyme of the embryonic mouse urogenital sinus

1985 • 38 citations

Epithelial-stromal interactions in the adult bladder: Urothelial growth, differentiation, and maturation on culture fascsimiles of bladder stroma

1986 • 37 citations

Proliferation, growth, and differentiation of pulmonary epithelium in fetal mouse lung exposed transplacentally to dexamethasone.

1977 • 33 citations

Gland formation of human colon cancer cells combined with foetal rat mesenchyme in organ culture: an ultrastructural study

1987 • 33 citations

Expression of epithelial-like markers and class I major histocompatibility antigens by a murine carcinoma growing in the mammary gland and in metastases: orthotopic site effects.

1988 • 33 citations

Growth of mouse vaginal epithelial cells in culture: Functional integrity of the estrogen receptor system and failure of estrogen to induce proliferation

1987 • 32 citations

Steroid Receptors in Health and Disease

1988 • 31 citations

Differentiation of allantoic endoderm implanted into the presumptive digestive area in avian embryos. A study with organ-specific antigens

1984 • 30 citations

Linoleic acid, but not cortisol, stimulates accumulation of casein by mouse mammary epithelial cells in serum-free collagen gel culture.

1987 • 28 citations

Tissue Interactions in Tooth Development in vitro

1977 • 27 citations

Inhibition of tumor cell growth by aggregation of a tumor-associated glycolipid antigen: a close functional association between gangliotriaosylceramide and transferrin receptor in mouse lymphoma L-5178Y.

1985 • 26 citations

Morphogenesis of human colon cancer cells with fetal rat mesenchymes in organ culture

1986 • 26 citations

Comparison of metastasis of mammary tumors growing in the mammary fatpad versus the subcutis.

1981 • 26 citations

Collagen gel culture system and analysis of estrogen effects on mammary carcinogenesis

1984 • 25 citations

Proliferation of normal mouse uterine luminal epithelial cells in serum-free collagen gel culture.

1985 • 24 citations

Vaginal and uterine stroma maintain their inductive properties following primary cullture

1987 • 24 citations

Growth characteristics of primary cultures of stromal cells from human endometrium

1982 • 24 citations

Molecular and Developmental Biology Aspects of Fibroblast Growth Factor

1988 • 23 citations

Morphogenetic Tissue Interactions: An Introduction

1977 • 23 citations

The epithelial origin of a stromal cell population in adenocarcinoma of the rat prostate.

1987 • 22 citations

Estrogen Responsiveness and the Estrogen Receptor during Development of the Murine Female Reproductive Tract

1988 • 21 citations

Growth of mouse vaginal epithelial cells in culture: Effect of sera and supplemented serum-free media

1987 • 21 citations

Genetic regulation of the androgen receptor—A study of testicular feminization in the mouse

1975 • 20 citations

Induction of estrogen receptor, peroxidase activity, and epithelial abnormalities in the mouse uterovaginal epithelium after neonatal treatment with diethylstilbestrol

1988 • 19 citations

Acceleration of mammary cancer development by grafting of fetal mammary mesenchymes in C3H mice.

1979 • 18 citations

Platelet-Derived Growth Factor — Its Role in Health and Disease

1988 • 17 citations

STUDY OF ORGANOGENESIS BY DISSOCIATION AND REASSOCIATION OF EMBRYONIC RUDIMENTS IN VITRO

1970 • 13 citations

Immunocytochemistry of Estrogen and Progestin Receptors in the Primate Reproductive Tract

1988 • 12 citations

Interaction of epithelial and stromal cells in vaginal adenosis

1988 • 11 citations

DEVELOPMENT OF THE INFANTILE MOUSE UTERUS: THE EFFECT OF STILBOESTROL

1975 • 8 citations

Regulation of Cell Growth and Transformation by the Epidermal Growth Factor Receptor

1988 • 7 citations

Hormones and cancer 3

1988 • 6 citations

Kidney Tubule Induction: Physical and Chemical Interference

1977 • 4 citations

Deleted Work

1955 • 0 citations