Adenovirus E1A Functions as a Cofactor for Retinoic Acid Receptor β (RAR β) through Direct Interaction with RARβ

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Retinoic acid causes an anteroposterior transformation in the developing central nervous system

1989 • 885 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

Negative effect of the transcriptional activator GAL4

1988 • 672 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines.

1989 • 614 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

Retinoic acid receptors and cellular retinoid binding proteins: I. A systematic study of their differential pattern of transcription during mouse organogenesis

1990 • 587 citations

Activators and targets

1990 • 582 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation.

1994 • 531 citations

Retinoic acid receptors and cellular retinoid binding proteins : II. Their differential pattern of transcription during early morphogenesis in mouse embryos

1991 • 527 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors

1992 • 477 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

Determinants for selective RAR and TR recognition of direct repeat HREs.

1993 • 403 citations

A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein

1990 • 391 citations

Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor

1991 • 381 citations

Interaction of proteins with transcriptionally active estrogen receptors.

1994 • 379 citations

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

1993 • 369 citations

Teratocarcinomas as a model system for the study of embryogenesis and neoplasia

1975 • 361 citations

Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity.

1994 • 354 citations

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

1992 • 341 citations

Two human homologues ofSaccharomyces cerevisiae SWI2/SNF2andDrosophila brahmaare transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor

1994 • 338 citations

Common Control of the Heat Shock Gene and Early Adenovirus Genes: Evidence for a Cellular E1A-like Activity

1984 • 331 citations

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.

1993 • 328 citations

Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor.

1994 • 324 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.

1993 • 305 citations

Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains

1994 • 256 citations

Retinoids and vertebrate limb pattern formation

1989 • 251 citations

The p53 Activation Domain Binds the TATA Box-Binding Polypeptide in Holo-TFIID, and a Neighboring p53 Domain Inhibits Transcription

1993 • 246 citations

Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID.

1991 • 242 citations

Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets

1990 • 221 citations

The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

1993 • 218 citations

A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formation.

1994 • 207 citations

Mutational analysis of the adenovirus E1a gene: the role of transcriptional regulation in transformation.

1987 • 201 citations

E1A 13S and 12S mRNA Products Made in Escherichia coli Both Function as Nucleus-Localized Transcription Activators but Do Not Directly Bind DNA

1985 • 190 citations

Distinct TFIID complexes mediate the effect of different transcriptional activators.

1993 • 189 citations

A nexus between Oct-4 and E1 A: Implications for gene regulation in embryonic stem cells

1991 • 188 citations

ADENOVIRUS E1A PROTEIN PARADIGM VIRAL TRANSACTIVATOR

1989 • 184 citations

Retinoids, retinoid-responsive genes, cell differentiation, and cancer.

1992 • 158 citations

An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells

1987 • 149 citations

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

1993 • 146 citations

Eukaryotic coactivators associated with the TATA box binding protein

1992 • 142 citations

転写因子TF II Bとヒト甲状腺ホルモン受容体βとの結合は標的遺伝子の発現と甲状腺ホルモンによる活性化を仲介する

1993 • 135 citations

Functional analysis of a transactivation domain in the thyroid hormone beta receptor.

1994 • 123 citations

The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein.

1994 • 123 citations

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation.

1988 • 119 citations

Cooperativity in transactivation between retinoic acid receptor and TFIID requires an activity analogous to E1A

1992 • 116 citations

Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation.

1994 • 114 citations

A conserved C-terminal sequence that is deleted in v-ErbA is essential for the biological activities of c-ErbA (the thyroid hormone receptor).

1993 • 103 citations

Transcriptional Activation by the Adenovirus Larger E1a Product is Mediated by Members of the Cellular Transcription Factor ATF Family Which Can Directly Associate with E1a

1993 • 99 citations

Mouse Retinoid X Receptor Contains a Separable Ligand-Binding and Transactivation Domain in Its E Region

1995 • 95 citations

Mediators of activation of fushi tarazu gene transcription by BmFTZ-F1.

1994 • 91 citations

Endogenous Retinoic Acid Receptor (RAR)-Retinoid X Receptor (RXR) Heterodimers Are the Major Functional Forms Regulating Retinoid-responsive Elements in Adult Human Keratinocytes

1995 • 90 citations

Expression and interactions of human adenovirus oncoproteins

1991 • 88 citations

trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor.

1991 • 82 citations

Functional interaction of adenovirus E1A with holo-TFIID.

1993 • 79 citations

Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A.

1994 • 68 citations

Residues in the TATA-binding protein required to mediate a transcriptional response to retinoic acid in EC cells

1993 • 58 citations

A cyclic AMP response element is involved in retinoic acid-dependent RARβ2 promoter activation

1992 • 53 citations

Retinoic acid receptor and retinoid X receptor expression in retinoic acid—resistant human tumor cell lines

1993 • 50 citations

Positive regulation of jun/AP-1 by E1A.

1991 • 50 citations

The retinoic acid receptor-beta 2 contains two separate cell-specific transactivation domains, at the N-terminus and in the ligand-binding domain.

1993 • 40 citations

trans-Dominant Mutants of E1A Provide Genetic Evidence that the Zinc Finger of the trans-Activating Domain Binds a Transcription Factor

1991 • 37 citations

The Adenovirus Ela Gene Induces Differentiation of F9 Teratocarcinoma Cells

1987 • 32 citations

Transcriptional activation by the adenovirus E1A proteins

1993 • 24 citations

Mediators of Activation of fushi tarazu Gene Transcription by BmFTZ-Fl

1994 • 22 citations

Positive Regulation of jun/AP-1 by E1A

1991 • 21 citations

E1A functions as a coactivator of retinoic acid-dependent retinoic acid receptor-beta 2 promoter activation.

1993 • 20 citations

Presence of the adenovirus E1A-like activity in preimplantation stage mouse embryos.

1988 • 17 citations

CBF mediates adenovirus Ela trans-activation by interaction at the C-terminal promoter targeting domain of conserved region 3.

1994 • 16 citations

Adenovirus infection of differentiated F9 cells results in a global shut-off of differentiation-induced gene expression

1990 • 15 citations

Recombinant activation domains of virion protein 16 and human estrogen receptor generate transcriptional interference in vitro by distinct mechanisms.

1993 • 15 citations

Adenovirus 5 E1A induced differentiation of P19 embryonal carcinoma cells requires binding to p300.

1995 • 9 citations

A role for cofactors in synergistic and cell-specific activation by retinoic acid receptors and retinoid X receptor

1996 • 6 citations

Presence of the Adenovirus E1A-Like Activity in Preimplantation Stage Mouse Embryos

1988 • 2 citations