Recombinant activation domains of virion protein 16 and human estrogen receptor generate transcriptional interference in vitro by distinct mechanisms.

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

Negative effect of the transcriptional activator GAL4

1988 • 672 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

Transcription from a TATA-less promoter requires a multisubunit TFIID complex.

1991 • 618 citations

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

1988 • 588 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

Mechanism of action of an acidic transcriptional activator in vitro

1991 • 557 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer

1989 • 508 citations

The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain

1989 • 490 citations

Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex

1988 • 488 citations

Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID.

1988 • 477 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)

1990 • 346 citations

Commitment and activation at pol II promoters: A tail of protein-protein interactions

1990 • 332 citations

Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein

1988 • 325 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

1988 • 289 citations

Mutants of GAL4 protein altered in an activation function

1987 • 281 citations

A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors

1992 • 272 citations

Dissection of functional domains of the pituitary-specific transcription factor GHF-1

1989 • 252 citations

The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.

1991 • 249 citations

The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex

1990 • 223 citations

Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3.

1990 • 197 citations

The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions.

1988 • 176 citations

Advances in RNA polymerase II transcription

1992 • 149 citations

Hepatocyte-specific promoter element HP1 of the Xenopus albumin gene interacts with transcriptional factors of mammalian hepatocytes

1988 • 105 citations

Factors involved in specific transcription by mammalian RNA polymerase II: identification of general transcription factor TFIIG.

1990 • 92 citations

Jun and v-jun contain multiple regions that participate in transcriptional activation in an interdependent manner.

1989 • 82 citations

Human Progesterone Receptor Binding to Mouse Mammary Tumor Virus Deoxyribonucleic Acid: Dependence on Hormone and Nonreceptor Nuclear Factor(s)

1989 • 73 citations

A cell-specific activator in the Xenopus A2 vitellogenin gene: promoter elements functioning with rat liver nuclear extracts.

1988 • 48 citations

Developmental regulation and tissue distribution of the liver transcription factor LFB1 (HNF1) in Xenopus laevis.

1993 • 43 citations

Identification of a coactivator that increases activation of transcription by serum response factor and GAL4-VP16 in vitro.

1992 • 32 citations