The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein.

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

ADENOVIRUS PROMOTERS AND E1A TRANSACTIVATION

1986 • 460 citations

Crystal structure of TFIID TATA-box binding protein

1992 • 410 citations

A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein

1990 • 391 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor

1991 • 381 citations

Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter.

1992 • 372 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

Purification of a RAS-Responsive Adenylyl Cyclase Complex from Saccharomyces cerevisiae by Use of an Epitope Addition Method

1988 • 328 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Diverse transcriptional functions of the multisubunit eukaryotic TFIID complex.

1992 • 265 citations

The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.

1991 • 249 citations

Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID.

1991 • 242 citations

Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation

1993 • 234 citations

Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets

1990 • 221 citations

The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID

1992 • 195 citations

Distinct TFIID complexes mediate the effect of different transcriptional activators.

1993 • 189 citations

The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1

1993 • 185 citations

ADENOVIRUS E1A PROTEIN PARADIGM VIRAL TRANSACTIVATOR

1989 • 184 citations

Advances in RNA polymerase II transcription

1992 • 149 citations

The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation.

1988 • 119 citations

Transcriptional activation by simian virus 40 large T antigen: interactions with multiple components of the transcription complex.

1993 • 113 citations

Transcriptional Activation by the Adenovirus Larger E1a Product is Mediated by Members of the Cellular Transcription Factor ATF Family Which Can Directly Associate with E1a

1993 • 99 citations

Transcription Factor IID Mutants Defective for Interaction with Transcription Factor IIA

1992 • 95 citations

trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factor.

1991 • 82 citations

Functional dissection of TFIIB domains required for TFIIB–TFIID–promoter complex formation and basal transcription activity

1993 • 82 citations

Functional interaction of adenovirus E1A with holo-TFIID.

1993 • 79 citations

DNA-binding properties of an adenovirus 289R E1A protein.

1988 • 77 citations

Transcriptional Activation by Simian Virus 40 Large T Antigen: Interactions with Multiple Components of the Transcription Complex

1993 • 53 citations

trans-Dominant Mutants of E1A Provide Genetic Evidence that the Zinc Finger of the trans-Activating Domain Binds a Transcription Factor

1991 • 37 citations

An adenovirus type 5 E1A protein with a single amino acid substitution blocks wild-type E1A transactivation.

1987 • 34 citations

Conversion of the E1A Cys4 zinc finger to a nonfunctional His2,Cys2 zinc finger by a single point mutation.

1991 • 32 citations

An Adenovirus Type 5 ElA Protein with a Single Amino Acid Substitution Blocks Wild-Type ElA Transactivation

1987 • 15 citations