RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Retinoids and their receptors in differentiation, embryogenesis, and neoplasia

1991 • 856 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

1989 • 804 citations

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

1993 • 738 citations

The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors.

1986 • 733 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

A third human retinoic acid receptor, hRAR-gamma.

1989 • 686 citations

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

1991 • 672 citations

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

1988 • 588 citations

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

1992 • 583 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors.

1992 • 446 citations

Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor

1987 • 434 citations

MINIREVIEW: Interactions Among a Subfamily of Nuclear Hormone Receptors: The Regulatory Zipper Model

1990 • 428 citations

1,25-Dihydroxyvitamin D-Responsive Element and Glucocorticoid Repression in the Osteocalcin Gene

1989 • 418 citations

All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs

1992 • 417 citations

Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling.

1992 • 389 citations

TRANSCRIPTION ACTIVATION BY ESTROGEN AND PROGESTERONE RECEPTORS

1991 • 372 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

Retinoids Selective for Retinoid X Receptor Response Pathways

1992 • 342 citations

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

1992 • 341 citations

Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors.

1993 • 207 citations

Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein.

1992 • 137 citations

8 Retinoic Acid Receptors: Transcription Factors Modulating Gene Regulation, Development, and Differentiation

1992 • 107 citations

Heterodimerization of thyroid hormone (TH) receptor with H-2RIIBP (RXR beta) enhances DNA binding and TH-dependent transcriptional activation.

1992 • 88 citations

Activation of the phosphoenolpyruvate carboxykinase gene retinoic acid response element is dependent on a retinoic acid receptor/coregulator complex.

1992 • 88 citations

A retinoic acid response element from the rat CRBPI promoter is activated by an RARRXR heterodimer

1992 • 86 citations

Transcriptional regulation by the nuclear receptor superfamily

1992 • 43 citations

Activation of the Phosphoenolpyruvate Carboxykinase Gene Retinoic Acid Response Element Is Dependent on a Retinoic Acid Receptor/Coregulator Complex

1992 • 20 citations