Retinoic acid receptor and retinoid X receptor expression in retinoic acid—resistant human tumor cell lines

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Current protocols in molecular biology

1988 • 4,543 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

1990 • 1,349 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells

1980 • 1,094 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

1989 • 804 citations

Role of retinoids in differentiation and carcinogenesis.

1983 • 780 citations

A third human retinoic acid receptor, hRAR-gamma.

1989 • 686 citations

Molecular Analysis of Acute Promyelocytic Leukemia Breakpoint Cluster Region on Chromosome 17

1990 • 650 citations

A new retinoic acid receptor identified from a hepatocellular carcinoma

1988 • 613 citations

Retinoic acid is a negative regulator of AP-1-responsive genes.

1991 • 542 citations

Point mutations in the Human Vitamin D Receptor Gene Associated with Hypocalcemic Rickets

1988 • 490 citations

Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

1989 • 446 citations

All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs

1992 • 417 citations

Differential expression and ligand regulation of the retinoic acid receptor alpha and beta genes.

1989 • 403 citations

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

1991 • 395 citations

Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.

1991 • 390 citations

Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.

1991 • 373 citations

Retinoic Acid-Induced Neural Differentiation of Embryonal Carcinoma Cells

1983 • 308 citations

H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element.

1989 • 306 citations

Murine isoforms of retinoic acid receptor gamma with specific patterns of expression.

1990 • 304 citations

v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid.

1990 • 300 citations

A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma

1987 • 282 citations

Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta.

1989 • 261 citations

The concentration of retinoic acid determines the differentiated cell types formed by a teratocarcinoma cell line

1983 • 250 citations

Retinoic acid-induced neural differentiation of embryonal carcinoma cells.

1983 • 213 citations

Different susceptibilities of human melanoma and breast carcinoma cell lines to retinoic acid-induced growth inhibition.

1979 • 190 citations

Retinoic acid-resistant HL-60R cells harbor a point mutation in the retinoic acid receptor ligand-binding domain that confers dominant negative activity

1992 • 190 citations

Retinoids and cell differentiation

1986 • 187 citations

Cyclic AMP analogs and retinoic acid influence the expression of retinoic acid receptor alpha, beta, and gamma mRNAs in F9 teratocarcinoma cells.

1990 • 173 citations

Retinoids, retinoid-responsive genes, cell differentiation, and cancer.

1992 • 158 citations

Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation.

1991 • 155 citations

A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell.

1990 • 134 citations

Retinoic acid resistance of estradiol-independent breast cancer cells coincides with diminished retinoic acid receptor function

1993 • 126 citations

MINIREVIEW: Interactions of Retinoids and Transforming Growth Factor-β in Regulation of Cell Differentiation and Proliferation

1991 • 118 citations

Expression of a retinoic acid receptor gene in myeloid leukemia cells.

1989 • 107 citations

The Influence of a Hypervitaminosis on the Effect of 20-Methylcholanthrene on Mouse Prostate Glands Grown In Vitro

1955 • 106 citations

Retinoid-sensitive cells and cell lines

1990 • 80 citations

Retinoic acid receptor expression vector inhibits differentiation of F9 embryonal carcinoma cells.

1989 • 79 citations

Commitment to differentiation induced by retinoic acid in P19 embryonal carcinoma cells is cell cycle dependent

1987 • 76 citations

Modulation by Retinoids of mRNA Levels for Nuclear Retinoic Acid Receptors in Murine Melanoma Cells

1990 • 61 citations

Modulation of functional and optimal (Na⁺‐K⁺)ATPase activity during the cell cycle of neuroblastoma cells

1981 • 50 citations

Transcriptional regulation of retinoic acid receptor β in retinoic acid-sensitive and -resistant P19 embryocarcinoma cells

1991 • 49 citations

Effect of retinoic acid and 4-hydroxytamoxifen on human breast cancer cell lines

1984 • 48 citations

Retinoic acid resistance of the variant embryonal carcinoma cell line RAC65 is caused by expression of a truncated RARα

1992 • 43 citations

Retinoic acid receptors in myeloid leukemia: characterization of receptors in retinoic acid-resistant K-562 cells

1991 • 34 citations

Retinoic acid regulation of the expression of retinoic acid receptors in wild‐type and mutant embryonal carcinoma cells

1989 • 30 citations

Inhibition of mitogen-induced c-fos expression in melanoma cells by retinoic acid involves the serum response element.

1992 • 22 citations

Retinoic acid receptor alpha suppresses polyomavirus transformation and c-fos expression in rat fibroblasts.

1992 • 16 citations

Alterations of cellular characteristics of a human ovarian teratocarcinoma cell line after in vitro treatment with retinoids

1990 • 11 citations