Syndecan-1 expression by stromal fibroblasts promotes breast carcinoma growth in vivo and stimulates tumor angiogenesis

Functions of Cell Surface Heparan Sulfate Proteoglycans

1999 • 2,660 citations

Crystal Structure of a Ternary FGF-FGFR-Heparin Complex Reveals a Dual Role for Heparin in FGFR Binding and Dimerization

2000 • 1,146 citations

Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myeloma

2002 • 275 citations

Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican.

1996 • 273 citations

The syndecan-1 ectodomain regulates αvβ3 integrin activity in human mammary carcinoma cells

2004 • 234 citations

High syndecan‐1 expression in breast carcinoma is related to an aggressive phenotype and to poorer prognosis

2003 • 231 citations

Syndecan and tenascin expression is induced by epithelial-mesenchymal interactions in embryonic tooth mesenchyme.

1989 • 209 citations

Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors.

1994 • 194 citations

Soluble syndecan-1 promotes growth of myeloma tumors in vivo

2002 • 191 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody.

1985 • 185 citations

Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors

2005 • 183 citations

Epithelial-mesenchymal interactions regulate the stage-specific expression of a cell surface proteoglycan, syndecan, in the developing kidney

1989 • 149 citations

Heparan Sulfate Proteoglycans as Regulators of Fibroblast Growth Factor-2 Receptor Binding in Breast Carcinomas

2002 • 148 citations

Syndecan-1-mediated cell spreading requires signaling by αvβ3 integrins in human breast carcinoma cells

2003 • 143 citations

Induction of Syndecan-1 Expression in Stromal Fibroblasts Promotes Proliferation of Human Breast Cancer Cells

2004 • 138 citations

The cell surface proteoglycan syndecan-1 mediates fibroblast growth factor-2 binding and activity

1998 • 130 citations

Syndecan-1 (CD138) Immunoreactivity in Bone Marrow Biopsies of Multiple Myeloma: Shed Syndecan-1 Accumulates in Fibrotic Regions

2001 • 127 citations

Syndecan-1 Expression Is Induced in the Stroma of Infiltrating Breast Carcinoma

1999 • 125 citations

Transient expression of a cell surface heparan sulfate proteoglycan (syndecan) during limb development

1990 • 119 citations

Order and Disorder: The Role of Extracellular Matrix in Epithelial Cancer

2002 • 106 citations

Epithelial and stromal syndecan-1 expression as predictor of outcome in patients with gastric cancer

2001 • 104 citations

Shift of syndecan-1 expression from epithelial to stromal cells during progression of solid tumours

2004 • 77 citations

Fibroblast Growth Factor-2 Can Mediate Cell Attachment by Linking Receptors and Heparan Sulfate Proteoglycans on Neighboring Cells

1995 • 59 citations

Induced Expression of Syndecan-1 in the Stroma of Head and Neck Squamous Cell Carcinoma

2003 • 49 citations

Syndecan-1 Expression Is Decreased With Increasing Aggressiveness of Basal Cell Carcinoma

2000 • 44 citations

Syndecan-1 ectodomain regulates matrix-dependent signaling in human breast carcinoma cells

2004 • 33 citations

Syndecan-1 expression in thyroid carcinoma: stromal expression followed by epithelial expression is significantly correlated with dedifferentiation

2003 • 31 citations