The complexities of breast cancer desmoplasia

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction

1996 • 772 citations

Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia.

1993 • 511 citations

Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines.

1987 • 266 citations

Expression of growth factors, growth-inhibiting factors, and their receptors in invasive breast cancer. II: Correlations with proliferation and angiogenesis

1998 • 263 citations

Increased content of Type V Collagen in desmoplasia of human breast carcinoma.

1982 • 218 citations

Human breast carcinoma desmoplasia is PDGF initiated

2000 • 214 citations

Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 beta-estradiol or v-Ha-ras oncogene.

1987 • 199 citations

Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas

1999 • 187 citations

Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops

1998 • 175 citations

Transforming growth factor beta1 in ductal carcinoma in situ and invasive carcinomas of the breast

1992 • 154 citations

Frequent expression of growth factors for mesenchymal cells in human mammary carcinoma cell lines.

1987 • 151 citations

Growth Factor Synthesis and Human Breast Cancer Progression

1995 • 140 citations

Characterization of Cell-Associated and Soluble Forms of Connective Tissue Growth Factor (CTGF) Produced by Fibroblast CellsIn Vitro

1998 • 117 citations

Human Breast Carcinoma: Fibrin Deposits ans Desmoplasia. Inflammatory Cell Type and Distribution. Microvasculature and Infarction<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1981 • 104 citations

Insulin-like growth factor mediated stromal-epithelial interactions in human breast cancer

1994 • 98 citations

Myofibroblastic stromal reaction in carcinoma of the breast: variations of collagenous matrix and structural glycoproteins

1985 • 93 citations

Relationship of transforming growth factor β1 to extracellular matrix and stromal infiltrates in invasive breast carcinoma

1994 • 90 citations

Mitogenicity of human fibroblasts in vivo for human breast cancer cells

1987 • 89 citations

Multiple chemotactic factors: fine control or redundancy?

1999 • 79 citations

Different patterns of angiogenesis in sarcomas and carcinomas.

1999 • 66 citations

The ducts of carcinomatous breasts, with particular reference to connectivetissue changes

1957 • 47 citations

Histopathological characteristics and oestrogen receptor content in primary breast carcinoma

1981 • 25 citations

Tumours : wounds that do not heal.

2002 • 22 citations

Heterotransplants of Human Tumors in Nude Mice

2015 • 18 citations