Quantitative analysis of structural disorder in intervertebral disks using second harmonic generation imaging: comparison with morphometric analysis

Microfibrillar structure of type I collagen in situ

2006 • 862 citations

Imaging cells and extracellular matrix in vivo by using second-harmonic generation and two-photon excited fluorescence

2002 • 805 citations

Interpreting Second-Harmonic Generation Images of Collagen I Fibrils

2004 • 794 citations

The quantitative morphology of anisotropic trabecular bone

1974 • 561 citations

Connective tissue polarity. Optical second-harmonic microscopy, crossed-beam summation, and small-angle scattering in rat-tail tendon

1986 • 428 citations

Characterization of the Myosin-Based Source for Second-Harmonic Generation from Muscle Sarcomeres

2005 • 426 citations

3-Dimensional imaging of collagen using second harmonic generation

2003 • 416 citations

Polarization-Modulated Second Harmonic Generation in Collagen

2002 • 379 citations

Multiphoton microscopy in biological research

2001 • 366 citations

Invariance properties of Gabor filter-based features-overview and applications

2006 • 332 citations

3D microscopy of transparent objects using third‐harmonic generation

1998 • 298 citations

Nonenzymatic Glycation of Collagen in Aging and Diabetes

1998 • 234 citations

Second harmonic generation in collagen

1979 • 234 citations

Biological response of the intervertebral disc to dynamic loading

2003 • 224 citations

Polarization-dependent optical second-harmonic imaging of a rat-tail tendon

2002 • 223 citations

C<scp>ompu</scp>C<scp>ell</scp>, a multi-model framework for simulation of morphogenesis

2004 • 206 citations

Practical limits of resolution in confocal and non‐linear microscopy

2003 • 185 citations

The Collagen Fibril: The Almost Crystalline Structure

1998 • 171 citations

Quantitative second-harmonic generation microscopy in collagen

2003 • 163 citations

Image analysis of tendon helical superstructure using interference and polarized light microscopy

2003 • 143 citations

Nonenzymatic Glycation of Collagen in Aging and Diabetes

1991 • 138 citations

Collagen structure and nonlinear susceptibility: Effects of heat, glycation, and enzymatic cleavage on second harmonic signal intensity

2000 • 133 citations

Optical Clearing for Improved Contrast in Second Harmonic Generation Imaging of Skeletal Muscle

2005 • 130 citations

Characterization of collagen orientation in human dermis by two-dimensional second-harmonic-generation polarimetry

2004 • 129 citations

Trabecular bone morphology from micro-magnetic resonance imaging

1996 • 125 citations

Imaging of trabecular bone structure in osteoporosis

1999 • 118 citations

Evidence that Collagen Fibrils in Tendons Are Inhomogeneously Structured in a Tubelike Manner

2003 • 111 citations

Coherent anti‐stokes Raman scattering microscopy: A biological review

2006 • 111 citations

Optical second‐harmonic scattering in rat‐tail tendon

1981 • 110 citations

Second-harmonic microscopy of unstained living cardiac myocytes: measurements of sarcomere length with 20-nm accuracy

2004 • 102 citations

Thermally Induced Irreversible Conformational Changes in Collagen Probed by Optical Second Harmonic Generation and Laser-induced Fluorescence

2002 • 100 citations

A Global Relationship Between Trabecular Bone Morphology and Homogenized Elastic Properties

1998 • 100 citations

Determination of collagen fiber orientation in human tissue by use of polarization measurement of molecular second-harmonic-generation light

2004 • 98 citations

A random number generator for PC's

1990 • 95 citations

The effect of static in vivo bending on the murine intervertebral disc

2001 • 88 citations

Method-Based Differences in the Automated Analysis of the Three-Dimensional Morphology of Trabecular Bone

1997 • 85 citations

Single-molecule detection of biomolecules by surface-enhanced coherent anti-Stokes Raman scattering

2005 • 81 citations

Polarization-resolved second-harmonic-generation optical coherence tomography in collagen

2004 • 50 citations

Morphometric Analysis of Subchondral Bone of the Tibial Condyle in Osteoarthrosis

1993 • 44 citations

A Bayesian approach to subvoxel tissue classification in NMR microscopic images of trabecular bone

1994 • 39 citations

Structural Model of the Amyloid Fibril Formed by β₂-Microglobulin #21−31 Fragment Based on Vibrational Spectroscopy

2005 • 37 citations

Comparative Vibrational Spectroscopy of Intracellular Tau and Extracellular Collagen I Reveals Parallels of Gelation and Fibrillar Structure

2004 • 34 citations

Surface Structural Characterization of Protein- and Polymer-Modified Polystyrene Microspheres by Infrared−Visible Sum Frequency Generation Vibrational Spectroscopy and Scanning Force Microscopy

2004 • 32 citations

Distribution and Orientation of Bone in the Human Lumbar Vertebral Centrum

1992 • 32 citations

The analysis of fibre distributions in fibre reinforced materials*

1977 • 32 citations

Coherent optical harmonic generation in rat-tail tendon

1980 • 15 citations

&lt;title&gt;Imaging collagen orientation using polarization-modulated second harmonic generation&lt;/title&gt;

2002 • 14 citations

Semiautomated image segmentation of bone marrow biopsies by texture features and mathematical morphology.

2004 • 12 citations

Ex vivo assessment of trabecular bone structure from three-dimensional projection reconstruction mr micro-images

2003 • 10 citations

Effect of structural modification on second harmonic generation in collagen

2003 • 8 citations

Polarization-modulated second harmonic generation imaging: method for quantitative assessment of disorganization in anulus

2005 • 6 citations

Criticality found in a model for orientational ordering of protein arrays

1997 • 6 citations

Short-TE projection reconstruction NMR microscopy of trabecular bone

2001 • 3 citations

Second harmonic generation in collagen

2003 • 3 citations

Measurements of long-term periprosthetic bone changes around a unique composite implant.

1994 • 1 citations

Second-harmonic generation investigation of collagen thermal denaturation

2007 • 1 citations

Equivalence of the Ashkin-Teller and the four-state Potts-glass models of neural networks

2001 • 1 citations