RacF1, a Novel Member of the Rho Protein Family inDictyostelium discoideum, Associates Transiently with Cell Contact Areas, Macropinosomes, and Phagosomes

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

Identification of Two Distinct Mechanisms of Phagocytosis Controlled by Different Rho GTPases

1998 • 993 citations

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

1991 • 961 citations

Phosphoinositide 3-kinases: A conserved family of signal transducers

1997 • 944 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

1997 • 802 citations

Sequence dependence of protein isoprenylation

1991 • 580 citations

Rho GTPases

1998 • 534 citations

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

1991 • 477 citations

Requirements for Both Rac1 and Cdc42 in Membrane Ruffling and Phagocytosis in Leukocytes

1997 • 445 citations

Regulation of receptor-mediated endocytosis by Rho and Rac

1996 • 386 citations

Intracellular localization of the P21rho proteins.

1992 • 382 citations

Coronin involved in phagocytosis: Dynamics of particle-induced relocalization visualized by a green fluorescent protein tag

1995 • 353 citations

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.

1993 • 316 citations

Phagocytosis by zippers and triggers

1995 • 314 citations

Rho: a connection between membrane receptor signalling and the cytoskeleton

1996 • 271 citations

The Ras superfamily of GTPases ¹

1996 • 269 citations

Microfilament dynamics during cell movement and chemotaxis monitored using a GFP–actin fusion protein

1997 • 261 citations

Membrane Association and Targeting of Prenylated Ras-like GTPases

1998 • 259 citations

Fluid-phase uptake by macropinocytosis in Dictyostelium

1997 • 259 citations

Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.

1994 • 245 citations

Dynamic Distribution of Chemoattractant Receptors in Living Cells During Chemotaxis and Persistent Stimulation

1997 • 234 citations

Localization of p21-Activated Kinase 1 (PAK1) to Pinocytic Vesicles and Cortical Actin Structures in Stimulated Cells

1997 • 230 citations

Endosome dynamics regulated by a Rho protein

1996 • 225 citations

The Rho Small G Protein Family-Rho GDI System as a Temporal and Spatial Determinant for Cytoskeletal Control

1998 • 200 citations

Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins.

1991 • 195 citations

Alternative Developmental Pathways Determined by Environmental Conditions in the Cellular Slime Mold Dictyostelium discoideum

1969 • 189 citations

Rho is Required for the Initiation of Calcium Signaling and Phagocytosis by Fcγ Receptors in Macrophages

1997 • 170 citations

Isolation of Dictyostelium discoideum Cytokinesis Mutants by Restriction Enzyme-Mediated Integration of the Blasticidin S Resistance Marker

1994 • 169 citations

Chemoattractant-controlled accumulation of coronin at the leading edge of Dictyostelium cells monitored using a green fluorescent protein–coronin fusion protein

1995 • 163 citations

Regulation of Actin Polymerization in Cell-free Systems by GTPγS and Cdc42

1997 • 160 citations

A GENETIC STUDY OF AGGREGATION IN THE CELLULAR SLIME MOULD DICTYOSTELIUM DISCOIDEUM USING COMPLEMENTATION ANALYSIS

1976 • 150 citations

A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis.

1996 • 140 citations

Sequence organization inDictyostelium: unique structure at the 5′-ends of protein coding genes

1983 • 134 citations

Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase.

1993 • 130 citations

Electron microscopic mapping of monoclonal antibodies on the tail region of Dictyostelium myosin

1982 • 126 citations

PRK1 Is Targeted to Endosomes by the Small GTPase, RhoB

1998 • 112 citations

Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes.

1995 • 110 citations

Kinetics of endosomal pH evolution in Dictyostelium discoideum amoebae Study by fluorescence spectroscopy

1993 • 109 citations

Monoclonal antibodies prepared against Dictyostelium actin: characterization and interactions with actin.

1984 • 104 citations

Inactivation of Two Dictyostelium discoideum Genes, DdPIK1 and DdPIK2, Encoding Proteins Related to Mammalian Phosphatidylinositide 3-kinases, Results in Defects in Endocytosis, Lysosome to Postlysosome Transport, and Actin Cytoskeleton Organization

1997 • 102 citations

Overexpression of a Novel Rho Family GTPase, RacC, Induces Unusual Actin-based Structures and Positively Affects Phagocytosis inDictyostelium discoideum

1998 • 90 citations

Overexpression of the csa cell adhesion molecule under its own camp-regulated promoter impairs morphogenesis in dictyostelium

1992 • 89 citations

Cloning and Characterization of a Dictyostelium Myosin I Heavy Chain Kinase Activated by Cdc42 and Rac

1996 • 88 citations

Role of Dictyostelium racE in cytokinesis: mutational analysis and localization studies by use of green fluorescent protein.

1997 • 75 citations

Cloning and characterization of seven novel Dictyostelium discoideum rac-related genes belonging to the rho family of GTPases

1993 • 68 citations

TheDictyostelium cytoskeleton

1995 • 59 citations

Developmentally regulated transcription of Dictyostelium discoideum plasmid Ddp1

1985 • 49 citations

Dictyostelium discoideum cells lacking the 34,000-dalton actin-binding protein can grow, locomote, and develop, but exhibit defects in regulation of cell structure and movement: a case of partial redundancy.

1996 • 46 citations

Analysis of successive endocytic compartments isolated from Dictyostelium discoideum by magnetic fractionation

1994 • 41 citations

Small GTP-Binding Proteins of the Rho Family in the Dictyostelium Cytoskeleton

1998 • 2 citations