Role of Dictyostelium racE in cytokinesis: mutational analysis and localization studies by use of green fluorescent protein.

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer

1996 • 1,462 citations

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1990 • 1,049 citations

The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts

1995 • 1,033 citations

Sequence dependence of protein isoprenylation

1991 • 580 citations

A novel ras-related gene family

1985 • 487 citations

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

1991 • 477 citations

Bcr encodes a GTPase-activating protein for p21rac

1991 • 474 citations

The neck region of the myosin motor domain acts as a lever arm to generate movement.

1996 • 440 citations

Hypervariable C-termmal domain of rab proteins acts as a targeting signal

1991 • 394 citations

Intracellular localization of the P21rho proteins.

1992 • 382 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).

1993 • 363 citations

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.

1993 • 316 citations

Signal transduction and actin filament organization

1996 • 309 citations

Role of Protein Modification Reactions in Programming Interactions Between Ras-Related GTPases and Cell Membranes

1994 • 279 citations

On the mechanisms of cytokinesis in animal cells

1983 • 263 citations

Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins

1989 • 258 citations

Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity.

1993 • 256 citations

A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs

1993 • 230 citations

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP.

1991 • 211 citations

A Transformation Vector for Dictyostelium discoideum with a New Selectable Marker bsr

1993 • 198 citations

New horizons for cytokinesis

1995 • 196 citations

Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows.

1995 • 192 citations

A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila

1995 • 169 citations

Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs

1996 • 141 citations

A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis.

1996 • 140 citations

Probing the Structure and Mechanism of Ras Protein with an Expanded Genetic Code

1993 • 130 citations

The origin of cleavage forces in dividing eggs

1981 • 78 citations

Dominant Inhibitory Mutations in the Mg²⁺-Binding Site of Ras^H Prevent Its Activation by GTP

1991 • 68 citations

Cloning and characterization of seven novel Dictyostelium discoideum rac-related genes belonging to the rho family of GTPases

1993 • 68 citations

Expression of light meromyosin in Dictyostelium blocks normal myosin II function.

1995 • 23 citations