A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis.

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination

1987 • 984 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

Antisense RNA Inactivation of Myosin Heavy Chain Gene Expression in Dictyostelium discoideum

1987 • 677 citations

Chapter 2 Cultivation and Synchronous Morphogenesis of Dictyostelium under Controlled Experimental Conditions

1987 • 610 citations

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.

1990 • 605 citations

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.

1990 • 560 citations

Tagging developmental genes in Dictyostelium by restriction enzyme-mediated integration of plasmid DNA.

1992 • 484 citations

The effect of myosin antibody on the division of starfish blastomeres

1977 • 445 citations

GTPase cascades choreographing cellular behavior: Movement, morphogenesis, and more

1995 • 394 citations

Hypervariable C-termmal domain of rab proteins acts as a targeting signal

1991 • 394 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).

1993 • 363 citations

The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila

1991 • 281 citations

Capping of surface receptors and concomitant cortical tension are generated by conventional myosin

1989 • 274 citations

Cytokinesis

1992 • 239 citations

Dictyostelium amoebae that lack G-actin-sequestering profilins show defects in F-actin content, cytokinesis, and development

1994 • 233 citations

A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs

1993 • 230 citations

A defined minimal medium for axenic strains of Dictyostelium discoideum

1977 • 225 citations

Chapter 4 Molecular Biology in Dictyostelium: Tools and Applications

1987 • 223 citations

Phosphorylation of myosin-II regulatory light chain by cyclin-p34cdc2: a mechanism for the timing of cytokinesis.

1992 • 197 citations

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant.

1990 • 173 citations

Chapter 19 Agar-Overlay Immunofluorescence: High-Resolution Studies of Cytoskeletal Components and Their Changes during Chemotaxis

1987 • 138 citations

Evidence that myosin does not contribute to force production in chromosome movement.

1982 • 125 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI)

1994 • 100 citations

Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development.

1994 • 85 citations

Sequence, expression pattern, intracellular localization, and targeted disruption of the Dictyostelium myosin ID heavy chain isoform

1993 • 81 citations

Developmental consequences of the lack of myosin heavy chain in Dictyostelium discoideum

1988 • 71 citations

The dictyostelium essential light chain is required for myosin function

1992 • 68 citations

Cloning and characterization of seven novel Dictyostelium discoideum rac-related genes belonging to the rho family of GTPases

1993 • 68 citations

Dictyostelium discoideum mutants with conditional defects in phagocytosis.

1994 • 40 citations

Expression of light meromyosin in Dictyostelium blocks normal myosin II function.

1995 • 23 citations

Isolation and characterization of a novel cytokinesis-deficient mutant inDictyostelium discoideum

1996 • 16 citations

Role of the Mitotic Apparatus in Furrow Initiation^a

1990 • 13 citations

Myosin heavy chain dephosphorylation during cytokinesis in dividing sea urchin embryos

1993 • 8 citations