Overexpression of the csa cell adhesion molecule under its own camp-regulated promoter impairs morphogenesis in dictyostelium

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic culture

1970 • 1,142 citations

Direct Cloning and Sequence Analysis of Enzymatically Amplified Genomic Sequences

1986 • 766 citations

The pIC plasmid and phage vectors with versatile cloning sites for recombinant selection by insertional inactivation

1984 • 718 citations

DYNAMICS OF ANTIGENIC MEMBRANE SITES RELATING TO CELL AGGREGATION IN DICTYOSTELIUM DISCOIDEUM

1973 • 389 citations

Genetic Recombination in Escherichia coli: The Role of Exonuclease I

1971 • 330 citations

A specific glycoprotein as the target site of adhesion blocking Fab in aggregating Dictyostelium cells

1978 • 320 citations

Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells

1975 • 320 citations

PCR-based cDNA library construction: general cDNA libraries at the level of a few cells

1989 • 285 citations

DNA-Mediated Transformation in Dictyostelium discoideum: Regulated Expression of an Actin Gene Fusion

1984 • 277 citations

CYCLIC AMP AND OTHER SIGNALS CONTROLLING CELL DEVELOPMENT AND DIFFERENTIATION IN DICTYOSTELIUM

1987 • 240 citations

Developmental Regulation of Dictyostelium discoideum Actin Gene Fusions Carried on Low-Copy and High-Copy Transformation Vectors

1986 • 221 citations

AMPLIFICATION OF FLANKING SEQUENCES BY INVERSE PCR

1990 • 214 citations

DNA-mediated transformation in Dictyostelium discoideum: regulated expression of an actin gene fusion.

1984 • 199 citations

Viability of λ phages carrying a perfect palindrome in the absence of recombination nucleases

1983 • 166 citations

Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein.

1987 • 166 citations

Complete sequence and transcript regulation of a cell adhesion protein from aggregating Dictyostelium cells

1986 • 158 citations

A GENETIC STUDY OF AGGREGATION IN THE CELLULAR SLIME MOULD DICTYOSTELIUM DISCOIDEUM USING COMPLEMENTATION ANALYSIS

1976 • 150 citations

Developmental regulation of Dictyostelium discoideum actin gene fusions carried on low-copy and high-copy transformation vectors.

1986 • 139 citations

Sequence organization inDictyostelium: unique structure at the 5′-ends of protein coding genes

1983 • 134 citations

Selection of Dictyostelium mutants defective in cytoskeletal proteins: use of an antibody that binds to the ends of alpha-actinin rods.

1986 • 128 citations

Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors.

1985 • 127 citations

High-copy-number transformants and co-transformation in Dictyostelium

1985 • 126 citations

Cloning of Streptococcus pneumoniae DNA fragments in Escherichia coli requires vectors protected by strong transcriptional terminators

1987 • 126 citations

Carbohydrate and other epitopes of contact site A glycoprotein of Dictyostelium discoideum as characterized by monoclonal antibodies

1985 • 104 citations

Reverse transcription of mRNA byThermus aquaticusDNA polymerase

1989 • 97 citations

The surface cyclic AMP receptor in Dictyostelium. Levels of ligand-induced phosphorylation, solubilization, identification of primary transcript, and developmental regulation of expression.

1987 • 96 citations

The Organization and Expression of the Dictyostelium Genome

1982 • 84 citations

Identification of a DNA sequence element required for efficient expression of a developmentally regulated and cAMP-inducible gene of Dictyostelium discoideum

1987 • 80 citations

The cyclic nucleotide phosphodiesterase gene of Dictyostelium discoideum contains three promoters specific for growth, aggregation, and late development.

1990 • 79 citations

Ca2+-independent F-actin Capping Proteins

1989 • 68 citations

Cloning of Physarum actin sequences in an exonuclease-deficient bacterial host.

1985 • 63 citations

The expression of two transcripts of the phosphodiesterase gene during the development of Dictyostelium discoideum

1987 • 60 citations

Regulation of the Discoidin I γ Gene in Dictyostelium discoideum: Identification of Individual Promoter Elements Mediating Induction of Transcription and Repression by Cyclic AMP

1990 • 57 citations

A developmentally regulated trans-acting factor recognizes dissimilar G/C-rich elements controlling a class of cAMP-inducible Dictyostelium genes.

1990 • 57 citations

Probing an adhesion mutant of Dictyostelium discoideum with cDNA clones and monoclonal antibodies indicates a specific defect in the contact site A glycoprotein

1985 • 53 citations

Developmental and spatial regulation of a Dictyostelium prespore gene: cis-acting elements and a cAMP-induced, developmentally regulated DNA binding activity

1991 • 50 citations

Early Dictyostelium Development: Control Mechanisms Bypassed by Sequential Mutagenesis

1985 • 47 citations

An 80-bp cis-acting regulatory region controls cAMP and development regulation of a prestalk gene in Dictyostelium.

1988 • 46 citations

Constitutive overexpression of the contact site A glycoprotein enables growth-phase cells of Dictyostelium discoideum to aggregate.

1990 • 42 citations

The Cyclic Nucleotide Phosphodiesterase Gene of Dictyostelium discoideum Utilizes Alternate Promoters and Splicing for the Synthesis of Multiple mRNAs

1989 • 41 citations

A colony-blot technique for the detection of specific transcripts in eukaryotes

1989 • 39 citations

Detection of developmentally controlled plasma membrane antigens of dictyostelium discoideum cells in SDS‐polyacrylamide gels

1978 • 39 citations

Cell‐cell adhesion molecules in Dictyostelium

1990 • 38 citations

Two-step glycosylation of the contact site A protein of Dictyostelium discoideum and transport of an incompletely glycosylated form to the cell surface.

1987 • 38 citations

Identification of a cis-acting element controlling induction of early gene expression in Dictyostelium discoideum.

1989 • 36 citations

Inter-relation of cell adhesion and differentiation in dictyostelium discoideum

1986 • 36 citations

Chapter 20 Cell Adhesion: Its Quantification, Assay of the Molecules Involved, and Selection of Defective Mutants in Dictyostelium and Polysphondylium

1987 • 32 citations

Signal transduction pathways controlling multicellular development in Dictyostelium

1991 • 30 citations

Superinduction of the Dictyostelium discoideum cell surface cAMP receptor by pulses of cAMP.

1987 • 25 citations

A Pharmacologically Distinct Cyclic AMP Receptor Is Responsible for the Regulation of gp80 Expression in Dictyostelium discoideum

1990 • 22 citations

Re-expression of 117 antigen, a cell surface glycoprotein of aggregating cells, during terminal differentiation of Dictyostelium discoideum prespore cells

1989 • 22 citations

The cyclic nucleotide phosphodiesterase gene of Dictyostelium discoideum utilizes alternate promoters and splicing for the synthesis of multiple mRNAs.

1989 • 21 citations

[28] Screening for Dictyostelium mutants defective in cytoskeletal proteins by colony immunoblotting

1991 • 18 citations

Developmental regulation of the cyclic‐nucleotide‐phosphodiesterase mRNA of Dictyostelium discoideum

1984 • 17 citations

Purification and properties of a secreted and developmentally regulated alpha-L-fucosidase from Dictyostelium discoideum.

1992 • 17 citations

A cis-acting element responsible for early gene induction by extracellular cAMP in Dictyostelium discoideum

1991 • 15 citations

Analysis of cis and trans elements involved in cAMP‐inducible gene expression in Dictyostelium discoideum

1988 • 15 citations

Transcript and sequence analysis of a 5.1 kb contiguous fragment of Dictyostelium discoideum plasmid Ddp1 that contains the origin of replication and codes for several transcripts

1990 • 14 citations

Regulation of discoidin I gene expression in dictyostelium discoideum by cell‐cell contact and cAMP

1985 • 11 citations