B7 Family Molecules Are Favorably Positioned at the Human Maternal-Fetal Interface1

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

2000 • 4,853 citations

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

2002 • 4,625 citations

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

1992 • 2,906 citations

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

2002 • 2,879 citations

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

2001 • 2,746 citations

Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor

1999 • 2,574 citations

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism

1998 • 2,538 citations

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

1999 • 2,380 citations

The Pathology of the Human Placenta

1967 • 2,145 citations

Autoimmune Dilated Cardiomyopathy in PD-1 Receptor-Deficient Mice

2001 • 1,761 citations

Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

1996 • 1,473 citations

The B7 and CD28 receptor families

1994 • 1,342 citations

CTLA-4–Ig regulates tryptophan catabolism in vivo

2002 • 1,150 citations

CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy

2001 • 964 citations

Blockade of Programmed Death-1 Ligands on Dendritic Cells Enhances T Cell Activation and Cytokine Production

2003 • 933 citations

B7-H3: A costimulatory molecule for T cell activation and IFN-γ production

2001 • 916 citations

The B7 Family of Ligands and Its Receptors: New Pathways for Costimulation and Inhibition of Immune Responses

2002 • 884 citations

B7-Dc, a New Dendritic Cell Molecule with Potent Costimulatory Properties for T Cells

2001 • 850 citations

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

2001 • 786 citations

The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro.

1994 • 607 citations

PD-1: an inhibitory immunoreceptor involved in peripheral tolerance

2001 • 467 citations

CD28/B7 Costimulation: A Review

1998 • 447 citations

Mature microglia resemble immature antigen-presenting cells

1998 • 339 citations

Surface Expression of HLA-C Antigen by Human Extravillous Trophoblast

2000 • 284 citations

Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS

2000 • 249 citations

B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function

2001 • 220 citations

Isolation of pure villous cytotrophoblast from term human placenta using immunomagnetic microspheres

1989 • 218 citations

TRAIL (Apo-2L) and TRAIL Receptors in Human Placentas: Implications for Immune Privilege

1999 • 191 citations

Functional regulation of human trophoblast differentiation

1998 • 174 citations

Impaired production of gamma-interferon by newborn cells in vitro is due to a functionally immature macrophage.

1985 • 172 citations

Recognition of Trophoblast HLA Class I Molecules by Decidual NK Cell Receptors—A Review

2000 • 159 citations

CD28: a signalling perspective

1996 • 156 citations

Activation-Induced Expression of Human Programmed Death-1 Gene in T-Lymphocytes

1997 • 144 citations

Uterine leukocytes: key players in pregnancy

2000 • 129 citations

TGF-beta attenuates the class II transactivator and reveals an accessory pathway of IFN-gamma action.

1997 • 127 citations

Differential expression and function of CD80 (B7‐1) and CD86 (B7‐2) on human peripheral blood monocytes

1996 • 127 citations

Death-Inducing Tumour Necrosis Factor (TNF) Superfamily Ligands and Receptors are Transcribed in Human Placentae, Cytotrophoblasts, Placental Macrophages and Placental Cell Lines

2001 • 111 citations

B7 Family Molecules: Novel Immunomodulators at the Maternal-Fetal Interface

2002 • 110 citations

Immunohistologic evidence that villitis in human normal term placentas is an immunologic lesion

1990 • 97 citations

Susceptibility of human trophoblast to killing by human complement and the role of the complement regulatory proteins.

1993 • 97 citations

Mechanisms of tolerance to self

1996 • 94 citations

Decidual macrophages are potentially susceptible to inhibition by class Ia and class Ib HLA molecules

2002 • 93 citations

Immunohistochemical Localization of Interferons in Human Placental Tissues in Normal, Ectopic, and Molar Pregnancy

1990 • 92 citations

The CTLA-4 gene is expressed in placental fibroblasts

1999 • 80 citations

Enhanced Expression of CD80 (B7-1), CD86 (B7-2), and CD40 and Their Ligands CD28 and CD154 in Fulminant Hepatic Failure

1999 • 80 citations

T cell co-stimulation and in vivo tolerance

1993 • 77 citations

Cutting Edge: Anti-Inflammatory Properties of Low Levels of IFN-γ

2002 • 77 citations

Neonatal dendritic cells

1998 • 75 citations

Interferon-γ gene expression in cycling and pregnant mouse uterus: temporal aspects and cellular localization

1998 • 75 citations

Role of CD28 in Acute Graft-Versus-Host Disease

1998 • 75 citations

The Role of B7-1 and B7-2 Costimulation for the Generation of CTL Responses In Vivo

1998 • 73 citations

Cytokine regulation of HLA-G expression in human trophoblast cell lines

1995 • 65 citations

Cells bearing class II MHC antigens in the human placenta and amniochorion.

1986 • 61 citations

Cultured Human Decidual Stromal Cells Express B7-1 (CD80) and B7-2 (CD86) and Stimulate Allogeneic T Cells1

1997 • 56 citations

Role of CD28 in Acute Graft-Versus-Host Disease

1998 • 52 citations

Mouse placental macrophages have a decreased ability to present antigen.

1993 • 50 citations

Evaluation of human chorionic trophoblast cells and placental macrophages as stimulators of maternal lymphocyte proliferation in vitro

1984 • 42 citations

Tamura, H. et al. B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood 97, 1809-1816

2001 • 40 citations

Separate precursor cells for macrophages and microglia in mouse brain: immunophenotypic and immunoregulatory properties of the progeny

1999 • 30 citations

Host B7-1 and B7-2 costimulatory molecules contribute to the eradication of B7-1-transfected P815 tumor cells via a CD8+ T cell-dependent mechanism.

1999 • 28 citations

Host B7-1 and B7-2 Costimulatory Molecules Contribute to the Eradication of B7-1-Transfected P815 Tumor Cells Via a CD8+ T Cell-Dependent Mechanism

1999 • 25 citations

Expression of HLA-DR, CAM and co-stimulatory molecules on cord blood monocytes

2001 • 17 citations

Amniochorion: Immunologic Aspects—A Review

1989 • 17 citations

Adoptive transfer of cytotoxic T lymphocytes induced by CD86-transfected tumor cells suppresses multi-organ metastases of C1300 neuroblastoma in mice

1997 • 17 citations

Deleted Work

1955 • 0 citations