Characterization of the Proteasome Regulator PA28

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution

1995 • 1,513 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

The crystal structure of the bacterial chaperonln GroEL at 2.8 Å

1994 • 1,322 citations

Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

1995 • 862 citations

A viral inhibitor of peptide transporters for antigen presentation

1995 • 599 citations

The multicatalytic and 26 S proteases.

1993 • 476 citations

The multicatalytic proteinase complex, a major extralysosomal proteolytic system

1990 • 464 citations

Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain).

1992 • 439 citations

The crystal structure of the GroES co-chaperonin at 2.8 Å resolution

1996 • 436 citations

Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm.

1994 • 395 citations

Proteasomes: multicatalytic proteinase complexes

1993 • 395 citations

Purification of an 11 S regulator of the multicatalytic protease.

1992 • 384 citations

Structural Features of the 26 S Proteasome Complex

1993 • 255 citations

Identification, purification, and characterization of a high molecular weight, ATP-dependent activator (PA700) of the 20 S proteasome.

1994 • 238 citations

Multiple forms of the 20 S multicatalytic and the 26 S ubiquitin/ATP-dependent proteases from rabbit reticulocyte lysate.

1992 • 229 citations

Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.

1994 • 220 citations

Primary structures of two homologous subunits of PA28, a γ‐interferon‐inducible protein activator of the 20S proteasome

1995 • 196 citations

In Vivo Assembly of the Proteasomal Complexes, Implications for Antigen Processing

1995 • 193 citations

Proteasomes are regulated by interferon gamma: implications for antigen processing.

1992 • 177 citations

Molecular cloning and expression of a gamma-interferon-inducible activator of the multicatalytic protease.

1994 • 175 citations

PA28 Activator Protein Forms Regulatory Caps on Proteasome Stacked Rings

1994 • 167 citations

Molecular Characterization of the "26S" Proteasome Complex from Rat Liver

1993 • 131 citations

Ubiquitin C-terminal hydrolase activity associated with the 26 S protease complex.

1993 • 125 citations

Identification of an additional gene required for eukaryotic nonsense mRNA turnover.

1995 • 113 citations

Purification and characterization of a multiprotein component of the Drosophila 26 S (1500 kDa) proteolytic complex.

1993 • 108 citations

The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif

1995 • 94 citations

PA28, an activator of the 20 S proteasome, is inactivated by proteolytic modification at its carboxyl terminus.

1993 • 86 citations

Activation of the multicatalytic protease. The 11 S regulator and 20 S ATPase complexes contain distinct 30-kilodalton subunits

1994 • 76 citations

PA28, an activator of the 20 S proteasome, is composed of two nonidentical but homologous subunits.

1994 • 62 citations

Purification and characterization of a multicatalytic proteinase from crustacean muscle: Comparison of latent and heat-activated forms

1989 • 58 citations