Purification and characterization of a multicatalytic proteinase from crustacean muscle: Comparison of latent and heat-activated forms

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

1982 • 1,024 citations

Preparation and properties of plasma membrane and endoplasmic reticulum fragments from isolated rat fat cells

1971 • 838 citations

Purification of two high molecular weight proteases from rabbit reticulocyte lysate.

1987 • 542 citations

INTRACELLULAR PROTEASES

1987 • 460 citations

Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome)

1988 • 404 citations

Evidence that Pituitary Cation‐Sensitive Neutral Endopeptidase Is a Multicatalytic Protease Complex

1983 • 356 citations

A high molecular weight protease in the cytosol of rat liver. I. Purification, enzymological properties, and tissue distribution.

1986 • 327 citations

Calcium‐activated neutral protease and its endogenous inhibitor Activation at the cell membrane and biological function

1987 • 273 citations

Purification of a liver alkaline protease which degrades oxidatively modified glutamine synthetase. Characterization as a high molecular weight cysteine proteinase.

1985 • 244 citations

The multicatalytic proteinase of mammalian cells

1989 • 242 citations

Proteasomes (multi-protease complexes) as 20 S ring-shaped particles in a variety of eukaryotic cells.

1988 • 225 citations

Purification and characterization of a multicatalytic high-molecular-mass proteinase from rat skeletal muscle

1985 • 208 citations

Activation of the multicatalytic proteinase from rat skeletal muscle by fatty acids or sodium dodecyl sulphate

1985 • 184 citations

Drosophila small cytoplasmic 19S ribonucleoprotein is homologous to the rat multicatalytic proteinase

1988 • 179 citations

Electron microscopy and image analysis of the multicatalytic proteinase

1988 • 150 citations

Purification and characterization of a high molecular weight proteinase (macropain) from human erythrocytes

1986 • 107 citations

Isolation of two forms of the high‐molecular‐mass serine protease, ingensin, from porcine skeletal muscle

1985 • 84 citations

Molecular organization of a high molecular weight multi-protease complex from rat liver

1988 • 83 citations

Molt cycle-associated changes in calcium-dependent proteinase activity that degrades actin and myosin in crustacean muscle

1982 • 69 citations

A 20S particle ubiquitous from yeast to human

1987 • 67 citations

ATP-stimulated proteolysis in soluble extracts of BHK 21C13 cells

1988 • 60 citations

A high molecular weight protease in the cytosol of rat liver. II. Properties of the purified enzyme.

1986 • 56 citations

Involvement of proteasomes (multicatalytic proteinase) in ATP‐dependent proteolysis in rat reticulocyte extracts

1988 • 54 citations

Purification of the two forms of the high-molecular-weight neutral proteinase ingensin from rat liver

1986 • 46 citations

Ingensin, a High-Molecular-Mass Alkaline Protease from Rabbit Reticulocyte

1986 • 42 citations

Four Ca2+-dependent proteinase activities isolated from crustacean muscle differ in size, net charge, and sensitivity to Ca2+ and inhibitors.

1986 • 40 citations

An enzyme related to the high molecular weight multicatalytic proteinase, macropain, participates in a ubiquitin-mediated, ATP-stimulated proteolytic pathway in soluble extracts of BHK 21/C13 fibroblasts

1988 • 36 citations

A high-molecular-weight cysteine endopeptidase from rat skeletal muscle

1983 • 34 citations

Ingensin, a fatty acid-activated serine proteinase from rat liver cytosol

1986 • 33 citations

High‐molecular‐weight serine proteinase from lobster muscle that degrades myofibrillar proteins

1989 • 32 citations

A multicatalytic high-molecular-weight neutral endopeptidase from human kidney

1987 • 30 citations

Purification and Characterization of a High-Molecular-Weight Protease, Ingensin, from Human Placenta

1986 • 29 citations

Comparative studies on lens neutral endopeptidase and pituitary neutral proteinase: two closely similar enzymes

1986 • 25 citations