The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law

Philosophical transactions of the Royal Society of London. B

1886 • 9,893 citations

The Hippocampus as a Cognitive Map

1978 • 8,087 citations

Emotion Circuits in the Brain

2000 • 8,055 citations

LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS

1957 • 7,145 citations

The relation of strength of stimulus to rapidity of habit‐formation

1908 • 6,230 citations

A cognitive model of posttraumatic stress disorder

2000 • 5,420 citations

The Emotional Brain: The Mysterious Underpinnings of Emotional Life

2004 • 4,130 citations

Emotion, Decision Making and the Orbitofrontal Cortex

2000 • 3,415 citations

The effect of emotion on cue utilization and the organization of behavior.

1959 • 2,992 citations

Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.

1992 • 2,910 citations

Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval

2000 • 2,546 citations

The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis*

1986 • 2,235 citations

THE AMYGDALA MODULATES THE CONSOLIDATION OF MEMORIES OF EMOTIONALLY AROUSING EXPERIENCES

2004 • 2,192 citations

Hippocampus, space, and memory

1979 • 2,033 citations

Memory systems of the brain: A brief history and current perspective

2004 • 2,022 citations

Drives and the C. N. S. (conceptual nervous system).

1955 • 2,004 citations

Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective

2005 • 1,989 citations

The Hippocampal-VTA Loop: Controlling the Entry of Information into Long-Term Memory

2005 • 1,895 citations

Long-Term Potentiation and Memory

2004 • 1,888 citations

The molecular basis of CaMKII function in synaptic and behavioural memory

2002 • 1,855 citations

Neurobiology of Pavlovian Fear Conditioning

2001 • 1,769 citations

A cortical–hippocampal system for declarative memory

2000 • 1,668 citations

The emotional brain

2004 • 1,635 citations

Protection and Damage from Acute and Chronic Stress: Allostasis and Allostatic Overload and Relevance to the Pathophysiology of Psychiatric Disorders

2004 • 1,516 citations

Why sex matters for neuroscience

2006 • 1,488 citations

The stressed hippocampus, synaptic plasticity and lost memories

2002 • 1,458 citations

Human emotion and memory: interactions of the amygdala and hippocampal complex

2004 • 1,438 citations

Neuronal signalling of fear memory

2004 • 1,387 citations

Double Dissociation of Conditioning and Declarative Knowledge Relative to the Amygdala and Hippocampus in Humans

1995 • 1,386 citations

Fear conditioning induces associative long-term potentiation in the amygdala

1997 • 1,285 citations

Math Anxiety: Personal, Educational, and Cognitive Consequences

2002 • 1,266 citations

The Body Keeps the Score: Memory and the Evolving Psychobiology of Posttraumatic Stress

1994 • 1,223 citations

Flashbulb memories

1977 • 1,206 citations

Psychosomatic Disease and the "Visceral Brain"

1949 • 1,163 citations

Stress and glucocorticoids impair retrieval of long-term spatial memory

1998 • 1,156 citations

The role of emotion in decision-making: Evidence from neurological patients with orbitofrontal damage

2004 • 1,135 citations

Planting misinformation in the human mind: A 30-year investigation of the malleability of memory: Figure 1.

2005 • 1,127 citations

Emotional stress and eyewitness memory: A critical review.

1992 • 1,056 citations

The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive

1996 • 1,053 citations

Three dimensions of emotion.

1954 • 1,039 citations

Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation

1986 • 1,037 citations

Memory Formation: The Sequence of Biochemical Events in the Hippocampus and Its Connection to Activity in Other Brain Structures

1997 • 981 citations

Dissociation and the fragmentary nature of traumatic memories: Overview and exploratory study

1995 • 953 citations

Stimulation of Medial Prefrontal Cortex Decreases the Responsiveness of Central Amygdala Output Neurons

2003 • 926 citations

A Functional Magnetic Resonance Imaging Study of Amygdala and Medial Prefrontal Cortex Responses to Overtly Presented Fearful Faces in Posttraumatic Stress Disorder

2005 • 923 citations

Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus

2005 • 919 citations

Learning under stress: how does it work?

2006 • 893 citations

Role of locus coeruleus in attention and behavioral flexibility

1999 • 867 citations

Conjunctive representations in learning and memory: Principles of cortical and hippocampal function.

2001 • 843 citations

Three Cases of Enduring Memory Impairment after Bilateral Damage Limited to the Hippocampal Formation

1996 • 834 citations

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

1992 • 832 citations

Stress- and treatment-induced elevations of cortisol levels associated with impaired declarative memory in healthy adults

1996 • 814 citations

Emotional memory systems in the brain

1993 • 805 citations

Role of adrenal stress hormones in forming lasting memories in the brain

2002 • 805 citations

Two routes to emotional memory: Distinct neural processes for valence and arousal

2004 • 804 citations

Fear conditioning induces a lasting potentiation of synaptic currents in vitro

1997 • 772 citations

Physiological Characteristics of Capacity Constraints in Working Memory as Revealed by Functional MRI

1999 • 770 citations

Regional Cerebral Blood Flow in the Amygdala and Medial PrefrontalCortex During Traumatic Imagery in Male and Female Vietnam Veterans With PTSD

2004 • 766 citations

Enhanced memory for emotional material following stress-level cortisol treatment in humans

2001 • 759 citations

Network reset: a simplified overarching theory of locus coeruleus noradrenaline function

2005 • 756 citations

Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone

2005 • 749 citations

Acute cortisone administration impairs retrieval of long-term declarative memory in humans

2000 • 729 citations

The hippocampal memory indexing theory.

1986 • 692 citations

The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death

2000 • 690 citations

Interaction between the Amygdala and the Medial Temporal Lobe Memory System Predicts Better Memory for Emotional Events

2004 • 684 citations

The hippocampal memory indexing theory.

1986 • 682 citations

Inverted‐U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation

1992 • 671 citations

Glucocorticoids and the regulation of memory consolidation

2000 • 667 citations

Impaired Memory Retrieval after Psychosocial Stress in Healthy Young Men

2005 • 662 citations

Posttraumatic stress disorder: A state-of-the-science review

2005 • 661 citations

Enhanced Human Memory Consolidation With Post-Learning Stress: Interaction With the Degree of Arousal at Encoding

2003 • 647 citations

Cognitive therapy for post-traumatic stress disorder: development and evaluation

2004 • 645 citations

Imagination inflation: Imagining a childhood event inflates confidence that it occurred

1996 • 617 citations

Synaptic Plasticity in the Lateral Amygdala: A Cellular Hypothesis of Fear Conditioning

2001 • 609 citations

Neural circuits and mechanisms involved in Pavlovian fear conditioning: A critical review

2005 • 609 citations

Working memory and executive control

1996 • 605 citations

Induction of Synaptic Potentiation in Hippocampus by Patterned Stimulation Involves Two Events

1986 • 603 citations

Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys.

1996 • 599 citations

Catecholamine modulation of prefrontal cortical cognitive function

1998 • 596 citations

Fear extinction in rats: Implications for human brain imaging and anxiety disorders

2006 • 592 citations

NMDA receptors, place cells and hippocampal spatial memory

2004 • 591 citations

Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition.

2001 • 590 citations

Noise Stress Impairs Prefrontal Cortical Cognitive Function in Monkeys

1998 • 585 citations

Remembering one year later: Role of the amygdala and the medial temporal lobe memory system in retrieving emotional memories

2005 • 577 citations

Confidence, Not Consistency, Characterizes Flashbulb Memories

2003 • 577 citations

Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys

1994 • 574 citations

Delay-dependent impairment of a matching-to-place task with chronic and intrahippocampal infusion of the NMDA-antagonist D-AP5

1999 • 563 citations

Memory consolidation and the amygdala: a systems perspective

2002 • 562 citations

Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty

2003 • 553 citations

Amygdala Is Critical for Stress-Induced Modulation of Hippocampal Long-Term Potentiation and Learning

2001 • 533 citations

Lesions of the dorsal hippocampal formation interfere with background but not foreground contextual fear conditioning.

1994 • 527 citations

Behavioural stress facilitates the induction of long-term depression in the hippocampus

1997 • 501 citations

Glucocorticoid enhancement of memory requires arousal-induced noradrenergic activation in the basolateral amygdala

2006 • 488 citations

Reconsolidation of memory after its reactivation

1997 • 481 citations

Advances in second messenger and phosphoprotein research

1992 • 481 citations

Elements of a neurobiological theory of the hippocampus: the role of activity-dependent synaptic plasticity in memory

2003 • 474 citations

Phantom flashbulbs: False recollections of hearing the news about Challenger

1992 • 472 citations

The psychological significance of the concept of "arousal" or "activation."

1957 • 471 citations

Clinical Implications of Neuroscience Research in PTSD

2006 • 463 citations

Understanding contextual fear conditioning: insights from a two-process model

2004 • 460 citations

Are the neural substrates of memory the final common pathway in posttraumatic stress disorder (PTSD)?

2002 • 456 citations

The cognitive neuroscience og remembering

2001 • 455 citations

Role of the Amygdala in Decision‐Making

2003 • 454 citations

Experience‐dependent Facilitating Effect of Corticosterone on Spatial Memory Formation in the Water Maze

1997 • 448 citations

Epinephrine enhancement of human memory consolidation: Interaction with arousal at encoding

2003 • 448 citations

Behavioral stress impairs long-term potentiation in rodent hippocampus

1987 • 441 citations

Yerkes-Dodson: A Law for all Seasons

1994 • 438 citations

Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation.

1996 • 435 citations

How emotion enhances the feeling of remembering

2004 • 420 citations

The role of calmodulin as a signal integrator for synaptic plasticity

2005 • 418 citations

Prefrontal activity associated with working memory and episodic long-term memory

2002 • 415 citations

Stress: metaplastic effects in the hippocampus

1998 • 414 citations

A meta-analytic review of the effects of acute cortisol administration on human memory

2005 • 410 citations

Performing under pressure: stress and cognitive function

1999 • 407 citations

Change in rape narratives during exposure therapy for posttraumatic stress disorder

1995 • 407 citations

Thickness of ventromedial prefrontal cortex in humans is correlated with extinction memory

2005 • 401 citations

Phobias and preparedness: the selective, automatic, and encapsulated nature of fear

2002 • 394 citations

Corticosteroid effects in the brain: U-shape it

2006 • 393 citations

Characterization of Fear Memory Reconsolidation

2004 • 386 citations

Effects of Glucocorticoids and Norepinephrine on the Excitability in the Hippocampus

1989 • 383 citations

Exposing rats to a predator impairs spatial working memory in the radial arm water maze

1999 • 381 citations

Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders

2002 • 377 citations

Facilitation of time-dependent memory processes with posttrial epinephrine injections

1975 • 376 citations

Characteristics and content of intrusive memories in PTSD and their changes with treatment

2004 • 375 citations

The functional neuroanatomy of working memory: Contributions of human brain lesion studies

2005 • 373 citations

The nature of intrusive memories after trauma: the warning signal hypothesis

2002 • 373 citations

Stress, cognitive impairment and cell adhesion molecules

2004 • 370 citations

Locus coeruleus and regulation of behavioral flexibility and attention

2000 • 367 citations

Prefrontal Control of the Amygdala

2005 • 360 citations

The relationship between stress induced cortisol levels and memory differs between men and women

2001 • 359 citations

Metaplasticity: A new vista across the field of synaptic plasticity

1997 • 358 citations

Electrical Stimulation of Medial Prefrontal Cortex Reduces Conditioned Fear in a Temporally Specific Manner.

2004 • 349 citations

Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders

2001 • 346 citations

Stable hippocampal long-term potentiation elicited by ‘theta’ pattern stimulation

1987 • 345 citations

Trauma modulates amygdala and medial prefrontal responses to consciously attended fear

2005 • 345 citations

Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition

2004 • 343 citations

The Biology of Being Frazzled

1998 • 340 citations

Psychological stress impairs spatial working memory: Relevance to electrophysiological studies of hippocampal function.

1996 • 338 citations

Late-associativity, synaptic tagging, and the role of dopamine during LTP and LTD

2004 • 338 citations

Yeast and apoptosis

2002 • 337 citations

Synaptic Mechanisms of Associative Memory in the Amygdala

2005 • 335 citations

Dopamine D₁/D₅Receptors Gate the Acquisition of Novel Information through Hippocampal Long-Term Potentiation and Long-Term Depression

2006 • 332 citations

Enduring memory impairment in monkeys after ischemic damage to the hippocampus

1992 • 329 citations

Under the curve: Critical issues for elucidating D1 receptor function in working memory

2005 • 328 citations

The late maintenance of hippocampal LTP: Requirements, phases, ‘synaptic tagging’, ‘late-associativity’ and implications

2006 • 322 citations

Reconceptualizing arousal: Psychobiological states in motor performance.

1988 • 321 citations

Fear Conditioning Occludes LTP-Induced Presynaptic Enhancement of Synaptic Transmission in the Cortical Pathway to the Lateral Amygdala

2002 • 320 citations

Effects of glucocorticoids on hippocampal long‐term potentiation

1993 • 320 citations

Unwanted memories of assault: what intrusion characteristics are associated with PTSD?

2004 • 320 citations

Long-term potentiation in the amygdala: A cellular mechanism of fear learning and memory

2006 • 320 citations

Inhibition of the Amygdala: Key to Pathological States?

2003 • 317 citations

Emotionality and the Yerkes-Dodson Law.

1957 • 317 citations

Selective prefrontal cortical projections to the region of the locus coeruleus and raphe nuclei in the rhesus monkey

1984 • 316 citations

Stress-induced recovery of fears and phobias.

1985 • 315 citations

Trauma and Memory

2007 • 314 citations

Noradrenergic enhancement of long-term potentiation at mossy fiber synapses in the hippocampus

1988 • 314 citations

Nightmares and trauma: a comparison of nightmares after combat with lifelong nightmares in veterans

1984 • 311 citations

Pathological gambling: a comprehensive review of biobehavioral findings

2004 • 310 citations

The place of the hippocampus in fear conditioning

2003 • 308 citations

Acute Stress-induced Changes in Hippocampal/Prefrontal Circuits in Rats: Effects of Antidepressants

2003 • 303 citations

Neural activity associated with episodic memory for emotional context

2001 • 302 citations

An electrophysiological and neuroanatomical study of the medial prefrontal cortical projection to the midbrain raphe nuclei in the rat

1998 • 301 citations

Glucocorticoid Effects on Memory Retrieval Require Concurrent Noradrenergic Activity in the Hippocampus and Basolateral Amygdala

2004 • 298 citations

3 Regulation of ligand-gated ion channels by protein phosphorylation

1999 • 297 citations

Uptake of corticosterone by rat brain and its concentration by certain limbic structures

1969 • 297 citations

Protein Kinase C Overactivity Impairs Prefrontal Cortical Regulation of Working Memory

2004 • 297 citations

Hippocampal Place Cells Acquire Location-Specific Responses to the Conditioned Stimulus during Auditory Fear Conditioning

2003 • 297 citations

The formation of flashbulb memories

1994 • 295 citations

Long-term effects of social stress on brain and behavior: a focus on hippocampal functioning

2004 • 295 citations

Exposure to Acute Stress Blocks the Induction of Long-Term Potentiation of the Amygdala–Prefrontal Cortex PathwayIn Vivo

2003 • 294 citations

The Amygdala, Fear, and Memory

2003 • 294 citations

Dose-dependent effects of the dopamine D1 receptor agonists A77636 or SKF81297 on spatial working memory in aged monkeys.

1997 • 292 citations

The hippocampus mediates glucocorticoid-induced impairment of spatial memory retrieval: Dependence on the basolateral amygdala

2003 • 292 citations

Basolateral amygdala noradrenergic influence enables enhancement of memory consolidation induced by hippocampal glucocorticoid receptor activation

1999 • 291 citations

β-Adrenergic modulation of emotional memory-evoked human amygdala and hippocampal responses

2004 • 291 citations

Prefrontal and parietal contributions to spatial working memory

2005 • 286 citations

Amygdala Modulation of Multiple Memory Systems: Hippocampus and Caudate-Putamen

1998 • 285 citations

Noradrenaline and β-adrenoceptor agonists increase activity of voltage-dependent calcium channels in hippocampal neurons

1987 • 283 citations

Impaired memory retrieval correlates with individual differences in cortisol response but not autonomic response

2006 • 282 citations

Rapid glucocorticoid effects on excitatory amino acid levels in the hippocampus: a microdialysis study in freely moving rats

1999 • 282 citations

Mice, monkeys, men, and motives.

1953 • 281 citations

Exposing Rats to a Predator Blocks Primed Burst Potentiation in the HippocampusIn Vitro

1999 • 275 citations

Corticosteroid Modulation of Hippocampal Potentials: Increased Effect with Aging

1989 • 274 citations

Glucocorticoid Release and Memory Consolidation in Men and Women

2006 • 265 citations

Reinforcement of Early Long-Term Potentiation (Early-LTP) in Dentate Gyrus by Stimulation of the Basolateral Amygdala: Heterosynaptic Induction Mechanisms of Late-LTP

2001 • 264 citations

Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus

1998 • 260 citations

Opposing roles of type I and type II adrenal steroid receptors in hippocampal long-term potentiation

1995 • 259 citations

Corticolimbic blood flow in posttraumatic stress disorder during script-driven imagery

2005 • 258 citations

Biphasic Modulation of Hippocampal Plasticity by Behavioral Stress and Basolateral Amygdala Stimulation in the Rat

1999 • 253 citations

Conjunctive representations, the hippocampus, and contextual fear conditioning

2001 • 244 citations

Induction of hippocampal long-term potentiation using physiologically patterned stimulation

1986 • 242 citations

When less is more

2004 • 241 citations

Stress effects in the hippocampus: Synaptic plasticity and memory

2006 • 237 citations

Directing the mind's eye: prefrontal, inferior and medial temporal mechanisms for visual working memory

2005 • 237 citations

Noradrenergic Regulation of Synaptic Plasticity in the Hippocampal CA1 Region

1997 • 235 citations

Temporal dynamics of glutamate efflux in the prefrontal cortex and in the hippocampus following repeated stress: effects of pretreatment with saline or diazepam

1997 • 235 citations

Putting Fear in Its Place: Remapping of Hippocampal Place Cells during Fear Conditioning

2004 • 234 citations

Impairments of emotion and real-world complex behavior following childhood- or adult-onset damage to ventromedial prefrontal cortex

2006 • 231 citations

Role of adrenal steroid mineralocorticoid and glucocorticoid receptors in long-term potentiation in the CA1 field of hippocampal slices

1996 • 230 citations

Topographic organization of connections between the hypothalamus and prefrontal cortex in the rhesus monkey

1998 • 230 citations

Correlation between the Pharmacology of Long-Term Potentiation and the Pharmacology of Memory

1995 • 228 citations

Mechanisms of Amygdala Modulation of Hippocampal Plasticity

2002 • 227 citations

Characterization of Ca2+ signals induced in hippocampal CA1 neurones by the synaptic activation of NMDA receptors.

1993 • 226 citations

Contribution of sex differences in the acute stress response to sex differences in water maze performance in the rat

2003 • 225 citations

Locus coeruleus-evoked responses in behaving rats: A clue to the role of noradrenaline in memory

1994 • 217 citations

Effects of oral cortisol treatment in healthy young women on memory retrieval of negative and neutral words

2004 • 215 citations

A functional neuroimaging study of motivation and executive function

2004 • 213 citations

Characteristics of hippocampal primed burst potentiation in vitro and in the awake rat

1988 • 212 citations

The impact of stress on neutral and emotional aspects of episodic memory

2006 • 211 citations

Influence of predator stress on the consolidation versus retrieval of long-term spatial memory and hippocampal spinogenesis

2006 • 209 citations

Acute stress impairs spatial memory in male but not female rats: influence of estrous cycle

2004 • 209 citations

Circuits and systems in stress. I. Preclinical studies

2002 • 208 citations

Priming of Long-Term Potentiation in Mouse Hippocampus by Corticotropin-Releasing Factor and Acute Stress: Implications for Hippocampus-Dependent Learning

2002 • 207 citations

Circuits and systems in stress. II. Applications to neurobiology and treatment in posttraumatic stress disorder

2002 • 204 citations

Corticosteroid Actions in the Hippocampus

2001 • 203 citations

Support for a Bimodal Role for Type II Adrenal Steroid Receptors in Spatial Memory

1999 • 200 citations

Biological Factors Associated with Susceptibility to Posttraumatic Stress Disorder

1999 • 198 citations

Stress Impairs LTP and Hippocampal‐Dependent Memorya

1994 • 193 citations

Stress impairs prefrontal cortical function in rats and monkeys: role of dopamine D1 and norepinephrine α-1 receptor mechanisms

2000 • 187 citations

Emotional tagging of memory formation—in the search for neural mechanisms

2003 • 186 citations

Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats

1994 • 185 citations

Functional neuroanatomy of executive processes involved in dual-task performance

2000 • 184 citations

A role for brain glucocorticoid receptors in contextual fear conditioning: dependence upon training intensity

1998 • 184 citations

Amygdalar Inactivation Blocks Stress-Induced Impairments in Hippocampal Long-Term Potentiation and Spatial Memory

2005 • 183 citations

Prior exposure to a single stress session facilitates subsequent contextual fear conditioning in rats

2003 • 182 citations

The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats

2002 • 181 citations

Damage to the hippocampal formation in rats selectively impairs the ability to learn cue relationships

1989 • 175 citations

Memory enhancement of classical fear conditioning by post-training injections of corticosterone in rats

2003 • 173 citations

The Amygdala, the Hippocampus, and Emotional Modulation of Memory

2004 • 172 citations

Hippocampal corticotropin releasing hormone: pre- and postsynaptic location and release by stress

2004 • 172 citations

NMDA Receptors Mediate Lasting Increases in Anxiety-Like Behavior Produced by the Stress of Predator Exposure—Implications for Anxiety Associated with Posttraumatic Stress Disorder

1998 • 171 citations

A Facilitative Role for Corticosterone in the Acquisition of a Spatial Task Under Moderate Stress

2004 • 168 citations

Psychological trauma: Burnt into memory

2002 • 168 citations

Hypodopaminergic and hypernoradrenergic activity in prefrontal cortex slices of an animal model for attention-deficit hyperactivity disorder — the spontaneously hypertensive rat

2002 • 167 citations

Emotion-Induced Amnesia in Rats: Working Memory-Specific Impairment, Corticosterone-Memory Correlation, and Fear Versus Arousal Effects on Memory

2003 • 165 citations

Calcium-dependent inactivation of synaptic NMDA receptors in hippocampal neurons

1995 • 162 citations

A selective role of calcineurin Aα in synaptic depotentiation in hippocampus

1999 • 162 citations

The effects of experimentally induced stress on false recognition

2002 • 160 citations

A Bias Toward Short-Term Thinking in Threat-Related Negative Emotional States

1999 • 160 citations

Timing is essential for rapid effects of corticosterone on synaptic potentiation in the mouse hippocampus

2006 • 159 citations

Corticosteroids and Hippocampal Plasticity

1994 • 158 citations

Long-Term Depression: A Cellular Basis for Learning?

2001 • 158 citations

Involvement of a Calcineurin Cascade in Amygdala Depotentiation and Quenching of Fear Memory

2003 • 158 citations

Endogenous acetylcholine lowers the threshold for long‐term potentiation induction in the CA1 area through muscarinic receptor activation: in vivo study

2004 • 157 citations

Personal Memories for Remote Historical Events: Accuracy and Clarity of Flashbulb Memories Related to World War II.

2005 • 156 citations

Effects of appraisal and coping on the neuroendocrine response to extreme stress

2005 • 156 citations

Neural plasticity, neuropeptides and anxiety in animals — implications for understanding and treating affective disorder following traumatic stress in humans

1998 • 155 citations

Noradrenergic Modulation of Emotion-Induced Forgetting and Remembering

2005 • 154 citations

Acute Activation of Hippocampal Glucocorticoid Receptors Results in Different Waves of Gene Expression Throughout Time

2006 • 154 citations

Autobiographic memory impairment following acute cortisol administration

2003 • 152 citations

The amygdala's role in long-term declarative memory for gist and detail.

2001 • 152 citations

The Role and Mechanisms of Action of Glucocorticoid Involvement in Memory Storage

1998 • 151 citations

A post-tetanic time window for the reinforcement of long-term potentiation by appetitive and aversive stimuli

1997 • 151 citations

Tunnel memory for traumatic events

1998 • 150 citations

Stressor Controllability Modulates Stress-Induced Dopamine and Serotonin Efflux and Morphine-Induced Serotonin Efflux in the Medial Prefrontal Cortex

2003 • 149 citations

Imaging the mental components of a planning task

2001 • 149 citations

Novelty‐elicited, Noradrenaline‐dependent Enhancement of Excitability in the Dentate Gyrus

1997 • 145 citations

Sex-related impairment of memory for emotional events with β-adrenergic blockade

2002 • 143 citations

Activity and plasticity in the CA1, the dentate gyrus, and the amygdala following controllable vs. uncontrollable water stress

2005 • 141 citations

Role of the Basolateral Amygdala in Memory Consolidation

2003 • 141 citations

Plasticity at hippocampal to prefrontal cortex synapses is impaired by loss of dopamine and stress: Importance for psychiatric diseases

2004 • 139 citations

Corticosterone and stress reduce synaptic potentiation in mouse hippocampal slices with mild stimulation

2002 • 138 citations

Modulation of synaptic plasticity by stress and antidepressants

2002 • 138 citations

On the neural basis of focused and divided attention

2005 • 138 citations

Serotonin blocks the long-term potentiation induced by primed burst stimulation in the CA1 region of rat hippocampal slices

1992 • 137 citations

Rundown of N‐methyl‐D‐aspartate channels during whole‐cell recording in rat hippocampal neurons: role of Ca2+ and ATP.

1993 • 135 citations

PSA‐NCAM: an important regulator of hippocampal plasticity

2000 • 131 citations

Reliving, emotions, and fragmentation in the autobiographical memories of veterans diagnosed with PTSD

2003 • 129 citations

Hippocampal homosynaptic long-term depression/depotentiation induced by adrenal steroids

1995 • 127 citations

Stress-induced cortisol elevations are associated with impaired delayed, but not immediate recall

2005 • 127 citations

The History of Trauma in Psychiatry

1994 • 126 citations

Role of Ca²⁺‐stimulated adenylyl cyclases in LTP and memory formation

2001 • 125 citations

TMT, a predator odor, elevates mesoprefrontal dopamine metabolic activity and disrupts short-term working memory in the rat

2000 • 124 citations

High-frequency stimulation of the basolateral amygdala facilitates the induction of long-term potentiation in the dentate gyrus in vivo

1995 • 124 citations

Traumatic Memory Is Special

1998 • 124 citations

Competitive interactions between endogenous LTD and LTP in the hippocampus underlie the storage of emotional memories and stress-induced amnesia

2005 • 124 citations

Effects of Traumatic Stress on Brain Structure and Function: Relevance to Early Responses to Trauma

2005 • 123 citations

The amygdala's role in long-term declarative memory for gist and detail.

2001 • 122 citations

Memory Mechanisms in Posttraumatic Stress Disorder

2002 • 121 citations

Properties of vertebrate glutamate receptors: Calcium mobilization and desensitization

1992 • 120 citations

Acute stress-induced impairment of spatial memory is associated with decreased expression of neural cell adhesion molecule in the hippocampus and prefrontal cortex

2005 • 120 citations

Involvement of the amygdaloid complex in neuromodulatory influences on memory storage

1990 • 119 citations

The history and present status of the law of effect.

1947 • 118 citations

Consistency of memory for emotionally arousing events: A review of prospective and experimental studies

2005 • 117 citations

Effects of inescapable stress on LTP in the amygdala versus the dentate gyrus of freely behaving rats

2004 • 117 citations

Memory enhancement by a semantically unrelated emotional arousal source induced after learning

2005 • 117 citations

Novel Environments Enhance the Induction and Maintenance of Long-Term Potentiation in the Dentate Gyrus

2004 • 115 citations

Effects of stress and long-term potentiation (LTP) on subsequent LTP and the theta burst response in the dentate gyrus

1994 • 115 citations

Impulsitivity, caffeine, and task difficulty: A within-subjects test of the Yerkes-Dodson law

1994 • 114 citations

Enhanced Priming for Trauma-Related Material in Posttraumatic Stress Disorder.

2005 • 113 citations

Norepinephrine promotes long-term potentiation in the adult rat hippocampus in vitro

1999 • 112 citations

Regulation of Depotentiation and Long-term Potentiation in the Dentate Gyrus of Freely Moving Rats by Dopamine D2-like Receptors

2002 • 111 citations

Ischemic brain damage and memory impairment: A commentary

1996 • 111 citations

Emotional Memory

1998 • 110 citations

The Basomedial and Basolateral Amygdaloid Nuclei Contribute to the Induction of Long‐term Potentiation in the Dentate Gyrus In Vivo

1996 • 109 citations

Modulation of Hippocampal Long-Term Potentiation by the Amygdala: A Synaptic Mechanism Linking Emotion and Memory

2001 • 108 citations

Long-Term Effects of Brief Acute Stress on Cellular Signaling and Hippocampal LTP

2006 • 108 citations

Don’t get too excited: mechanisms of glutamate-mediated Purkinje cell death

2005 • 107 citations

Structural plasticity and tianeptine: cellular and molecular targets

2002 • 105 citations

The effects of sex and hormonal status on restraint-stress-induced working memory impairment

2006 • 104 citations

Bidirectional modulation of long-term potentiation by novelty-exploration in rat dentate gyrus

2003 • 104 citations

Serum corticosterone level predicts the magnitude of hippocampal primed burst potentiation and depression in urethane-anesthetized rats

1991 • 103 citations

Unpredictable and uncontrollable stress impairs neuronal plasticity in the rat hippocampus

1990 • 103 citations

Amygdala β-noradrenergic influence on hippocampal longterm potentiation in vivo

1997 • 101 citations

Modulation of hippocampal long-term potentiation and long-term depression by corticosteroid receptor activation

1994 • 101 citations

Repeated testing in eyewitness memory: a means to improve recall of a negative emotional event

1998 • 101 citations

Transient and persistent consequences of acute stress on long-term potentiation (LTP), synaptic efficacy, theta rhythms and bursts in area CA1 of the hippocampus

1997 • 100 citations

Synaptic Gating and ADHD: A Biological Theory of Comorbidity of ADHD and Anxiety

2004 • 98 citations

Eyewitnesses show hypermnesia for details about a violent event.

1988 • 98 citations

Corticotrophin‐releasing factor produces a long‐lasting enhancement of synaptic efficacy in the hippocampus

1998 • 98 citations

Stress, hippocampal plasticity, and spatial learning

2001 • 97 citations

Effects of mineralocorticoid and glucocorticoid receptors on long-term potentiation in the CA3 hippocampal field

1999 • 97 citations

Follow-up of a cross-national comparison on flashbulb and event memory for the September 11th attacks

2005 • 96 citations

Stress generates emotional memories and retrograde amnesia by inducing an endogenous form of hippocampal LTP

2004 • 96 citations

The functional anatomy of divided attention in amnestic mild cognitive impairment

2005 • 96 citations

Exposure to a novel environment interferes with the induction of hippocampal primed burst potentiation in the behaving rat

1990 • 96 citations

Differential effects of predator stress and the antidepressant tianeptine on physiological plasticity in the hippocampus and basolateral amygdala

2006 • 94 citations

Reduced basal CAMKII levels in hippocampal CA1 region: Possible cause of stress‐induced impairment of LTP in chronically stressed rats

2004 • 94 citations

Acute stress impairs (or induces) synaptic long‐term potentiation (LTP) but does not affect paired‐pulse facilitation in the stratum radiatum of rat hippocampus

1992 • 89 citations

Priming stimulation of locus coeruleus facilitates memory retrieval in the rat

1988 • 89 citations

Corticosterone shifts different forms of synaptic potentiation in opposite directions

2005 • 89 citations

Neural plasticity and stress induced changes in defense in the rat

2001 • 87 citations

Amygdala, Long-term Potentiation, and Fear Conditioning

2005 • 86 citations

Unusualness and Threat as Possible Causes of "Weapon Focus"

1998 • 85 citations

Acute stress increases calcium current amplitude in rat hippocampus: temporal changes in physiology and gene expression

2003 • 85 citations

Glucocorticoid receptor activation selectively hampers N-methyl-d-aspartate receptor dependent hippocampal synaptic plasticity in vitro

2005 • 84 citations

Development of Cerebral Cortex

1948 • 84 citations

Time-dependent blockade of STP and LTP in hippocampal slices following acute stress in mice

1997 • 83 citations

Noradrenergic modulation of cognitive function: clinical implications of anatomical, electrophysiological and behavioural studies in animal models

1993 • 82 citations

Modulation of behavioral inhibition in appetitive extinction following manipulation of adrenal steroids in rats: Implications for involvement of the hippocampus.

1979 • 82 citations

Cortisol has different effects on human memory for emotional and neutral stimuli

2003 • 82 citations

Reinforcement of rat hippocampal LTP by holeboard training

2005 • 82 citations

Environmentally-induced modification of the benzodiazepine/GABA receptor coupled chloride ionophore

1987 • 80 citations

Development of the Cerebral Cortex: XIV. Stress Impairs Prefrontal Cortical Function

1999 • 78 citations

Fear learning induces persistent facilitation of amygdala synaptic transmission

2005 • 76 citations

Visual search with biological threat stimuli: Accuracy, reaction times, and heart rate changes.

2005 • 75 citations

The relation of strength of stimulus to rapidity of habit-formation in the kitten.

1915 • 75 citations

Role of amygdala oscillations in the consolidation of emotional memories

2003 • 75 citations

Neural plasticity and emotional memory

1998 • 75 citations

Effects of item-specific and relational information on hypermnesic recall.

1989 • 74 citations

The induction of corticosteroid actions on membrane properties of hippocampal CA1 neurons requires protein synthesis

1991 • 72 citations

Comparing flashbulb memories of September 11 and the death of Princess Diana: effects of time delays and nationality

2003 • 72 citations

Priming stimulation in the basolateral amygdala modulates synaptic plasticity in the rat dentate gyrus

1999 • 71 citations

Effect of stress on prefrontal cortex function

2004 • 71 citations

Enhanced perceptual priming for neutral stimuli in a traumatic context: A pathway to intrusive memories?

2005 • 69 citations

Autobiographical memories for the September 11th attacks: Reconstructive errors and emotional impairment of memory

2004 • 69 citations

Preclinical research on stress, memory, and the brain in the development of pharmacotherapy for depression

2004 • 68 citations

Corticotropin-Releasing Factor Produces a Protein Synthesis–Dependent Long-Lasting Potentiation in Dentate Gyrus Neurons

2000 • 66 citations

Learning theory and neuropsychology: Configuring their disparate elements in the hippocampus.

1999 • 66 citations

Cortisol and Memory Retrieval in Humans: Influence of Emotional Valence

2004 • 64 citations

Corticosterone inhibits generation of long-term potentiation in rat hippocampal slice: involvement of brain-derived neurotrophic factor

2000 • 64 citations

Rapid desensitization determines the pharmacology of glutamate neurotoxicity

1994 • 64 citations

Autobiographical and event memory for 9/11: changes across one year

2003 • 63 citations

Central Autonomic Control of the Heart, Angina, and Pathogenic Mechanisms of Post-Myocardial Infarction Depression

1999 • 62 citations

A selective increase in phosphorylation of cyclic AMP response element-binding protein in hippocampal CA1 region of male, but not female, rats following contextual fear and passive avoidance conditioning

2004 • 62 citations

Other contents

1999 • 61 citations

Permissive Influence of Stress in the Expression of a U-Shaped Relationship between Serum Corticosterone Levels and Spatial Memory Errors in Rats

2006 • 60 citations

Short-term behavioral and electrophysiological consequences of underwater trauma

2000 • 60 citations

Bidirectional Modulation of Hippocampal Long-Term Potentiation under Stress and No-Stress Conditions in Basolateral Amygdala-Lesioned and Intact Rats

2005 • 59 citations

Locus coeruleus bursts induced by glutamate trigger delayed perforant path spike amplitude potentiation in the dentate gyrus

1992 • 58 citations

Caffeine and Cognitive Performance: The Nonlinear Yerkes-Dodson Law

1997 • 58 citations

Traumatic Memories are Not Necessarily Accurate Memories

2005 • 57 citations

Influence of immobilization stress on the levels of CaMKII and phospho-CaMKII in the rat hippocampus

2004 • 57 citations

Effect of corticosteroid hormones on electrical activity in rat hippocampus

1991 • 56 citations

Corticosterone Effects on Long-Term Potentiation in Mouse Hippocampal Slices

1994 • 56 citations

Traumatic memories: Empirical foundations, forensic and clinical implications.

1995 • 55 citations

Conjunctive representations in learning and memory: Principles of cortical and hippocampal function.

2001 • 54 citations

■ REVIEW : Stress and Sex Effects on Associative Learning: For Better or for Worse

1998 • 54 citations

Effects of item-specific and relational information on hypermnesic recall.

1989 • 53 citations

Individual Memories

1899 • 53 citations

Nicotine prevents stress‐induced enhancement of long‐term depression in hippocampal area CA1: Electrophysiological and molecular studies

2005 • 52 citations

A fresh look at the role of CaMKII in hippocampal synaptic plasticity and memory

2002 • 51 citations

Dimensions of Arousal: Wakefulness and Vigor

2002 • 49 citations

Why do some individuals develop social phobia? A review with emphasis on the neurobiological influences

2004 • 49 citations

The amygdala is part of the behavioural reinforcement system modulating long-term potentiation in rat hippocampus

2003 • 48 citations

Test Anxiety, Observation, and Range of Cue Utilization

1976 • 47 citations

Working memory for order information: Multiple cognitive and neural mechanisms

2005 • 47 citations

Effects of age on flashbulb memories.

2002 • 46 citations

Prefrontal lesions and attentional skills in childhood

2005 • 46 citations

The effect of acute stress on LTP and LTD induction in the hippocampal CA1 region of anesthetized rats at three different ages

2004 • 46 citations

Drinking after water deprivation prolongs “unsaturated” LTP in the dentate gyrus of rats

1995 • 46 citations

Repressed Memory Accusations: Devastated Families and Devastated Patients

1997 • 45 citations

Hippocampal–prefrontal encoding activation predicts whether words can be successfully recalled or only recognized

2006 • 45 citations

Do Stress and Long-Term Potentiation Share the Same Molecular Mechanisms?

2005 • 44 citations

NMDA-Dependent Modulation of Hippocampal Kainate Receptors by Calcineurin and Ca²⁺/Calmodulin-Dependent Protein Kinase

2000 • 44 citations

Functional neuroanatomy of executive processes involved in dual-task performance

2000 • 44 citations

The ecological study of memory

1997 • 43 citations

A Model of Prefrontal Cortex Dopaminergic Modulation during the Delayed Alternation Task

2002 • 43 citations

The supramammillary nucleus contributes to associative EPSP‐spike potentiation in the rat dentate gyrus in vivo

2001 • 41 citations

High-voltage-activated Ca2+ currents and the excitability of pyramidal neurons in the hippocampal CA3 subfield in rats depend on corticosterone and time of day

2001 • 40 citations

Children's memories in the wake of Challenger

1996 • 40 citations

Increased stress vulnerability after a prefrontal cortex lesion in female rats

2003 • 40 citations

Predator Exposure Produces Retrograde Amnesia and Blocks Synaptic Plasticity: Progress toward Understanding How the Hippocampus Is Affected by Stress

2000 • 39 citations

Basolateral Amygdala Interacts with Other Brain Regions in Regulating Glucocorticoid Effects on Different Memory Functions

2004 • 38 citations

Expression of egr-1 (zif268) mRNA in select fear-related brain regions following exposure to a predator

2005 • 38 citations

Measuring of extracellular cortisol and corticotropin-releasing hormone in the amygdala using immunosensor coupled microdialysis

2001 • 37 citations

Flashbulb memories: Conceptual and methodological issues

1995 • 36 citations

Cognitive, Endocrine and Mechanistic Perspectives on Non-Linear Relationships between Arousal and Brain Function

2005 • 35 citations

A REFORMULATION OF THE YERKES‐DODSON LAW

1965 • 35 citations

Long-Lasting Hippocampal Plasticity: Cellular Model for Memory Consolidation?

2001 • 34 citations

Peripheral modulation of learning and memory: enkephalins as a model system

1992 • 34 citations

Anxiolysis followed by anxiogenesis relates to coping and corticosterone after medial prefrontal cortical damage in rats

2003 • 33 citations

Psychobiology of posttraumatic stress disorder : a decade of progress

2006 • 33 citations

Flashbulb and Event Memory of September 11, 2001: Consistency, Confidence and Age Effects

2005 • 33 citations

The Uptake and Action of Corticosterone: Regional and Subcellular Studies on Rat Brain

1970 • 32 citations

Long-term potentiation in hippocampus of rats is enhanced by endogenous acetylcholine in a way that is independent of N-methyl-d-aspartate receptors

2001 • 31 citations

Cue utilization and drive level in albino rats.

1971 • 30 citations

Amnesia for Traumatic Events Among Recent Survivors: A Pilot Study

2003 • 30 citations

Eyewitness testimony

2001 • 30 citations

Memory for negatively arousing and neutral pictorial stimuli using a repeated testing paradigm

2002 • 30 citations

Traumatic amnesia, repression, and hippocampus injury due to emotional stress, corticosteroids and enkephalins.

1998 • 29 citations

The fate of traumatic memories in childhood and adulthood

1998 • 29 citations

Medial amygdala enhances synaptic transmission and synaptic plasticity in the dentate gyrus of rats in vivo

1995 • 29 citations

Searching for the neurobiology of the misinformation effect: Figure 1.

2005 • 28 citations

Motivation and Skin Temperature Biofeedback: Yerkes‐Dodson Revisited

1982 • 27 citations

The Enhancement of Hippocampal Primed Burst Potentiation by Dehydroepiandrosterone Sulfate (DHEAS) is Blocked by Psychological Stress

1999 • 27 citations

REPRESSED MEMORIES

1999 • 26 citations

Physiology and pathology of NMDA receptors.

2005 • 25 citations

Stress, sex, hippocampal plasticity: relevance to psychiatric disorders

2001 • 25 citations

THE PATHOLOGY OF INSANITY

1858 • 25 citations

Effect of LTP-reinforcing paradigms on neurotransmitter release in the dentate gyrus of young and aged rats

2004 • 25 citations

Factors That Determine the Non-Linear Amygdala Influence on Hippocampus-Dependent Memory

2006 • 25 citations

Inhibition of Calcium‐Dependent NMDA Receptor Current Rundown by Calbindin‐D_28k

1999 • 24 citations

Homeostatic Regulation of Glutamate Release in Response to Depolarization

2006 • 24 citations

Psychological stress impairs spatial working memory: Relevance to electrophysiological studies of hippocampal function.

1996 • 24 citations

The Induction of Long-Term Potentiation at Amygdalo-Hippocampal Synapses in Vivo

2003 • 23 citations

Modifiability of behavior in its relations to the age and sex of the dancing mouse

1909 • 23 citations

Implicit Memory in Posttraumatic Stress Disorder With Amnesia for the Traumatic Event

1998 • 23 citations

Retroactive hyperamnesia and other emotional effects on memory.

1919 • 19 citations

Dissociating veridicality, consistency, and confidence in autobiographical and event memories for theColumbiashuttle disaster

2006 • 16 citations

Implicación de los glucocorticoides en la consolidación de la memoria

2003 • 15 citations

Post-traumatic stress disorder and memory: prescient medicolegal testimony at the International War Crimes Tribunal?

2005 • 15 citations

Visual discrimination learning as a function of shock-fear and task difficulty.

1956 • 15 citations

Differential Effects of Stress on Hippocampal and Amygdaloid LTP: Insight Into the Neurobiology of Traumatic Memories

2000 • 14 citations

Supplementary report: The Yerkes-Dodson law and shift in task difficulty.

1960 • 13 citations

Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: Desensitization of N-Methyl-D-aspartate Receptor Channels

2005 • 13 citations

An experimental study of the influence of punishment for errors during learning upon retention.

1934 • 12 citations

Stress and long-term synaptic depression

1998 • 12 citations

Memory in Canadian Courts of Law.

2003 • 10 citations

Recognition and Selfhood

1995 • 9 citations

Parametric study of dopaminergic neuromodulatory effects in a reduced model of the prefrontal cortex

2004 • 7 citations

Effects of age on flashbulb memories.

2002 • 6 citations

The assassination of Yitzhak Rabin: Resonance of a national tragedy in psychotherapy.

1997 • 4 citations

Eyewitness recall, the Yerkes-Dodson law, and optimal-level theory.

1985 • 4 citations

A new mode beyond the inverted-U region of the dopaminergic modulation of the prefrontal cortex

2006 • 2 citations

Changes in in vivo [3H]-Ro15-4513 binding induced by forced swimming in mice

2005 • 2 citations

Incidental Cue Utilization as a Function of its Incentive-Produced Validity under Two Levels of Water Deprivation

1980 • 2 citations