The late maintenance of hippocampal LTP: Requirements, phases, ‘synaptic tagging’, ‘late-associativity’ and implications

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Long‐lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path

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Computational subunits in thin dendrites of pyramidal cells

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Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro

1988 • 800 citations

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Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage

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Synaptic tagging: implications for late maintenance of hippocampal long-term potentiation

1998 • 603 citations

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Expression of Constitutively Active CREB Protein Facilitates the Late Phase of Long-Term Potentiation by Enhancing Synaptic Capture

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2006 • 523 citations

Anisomycin blocks the late phase of long-term potentiation in the dentate gyrus of freely moving rats

1984 • 508 citations

Disruption of Dendritic Translation of CaMKIIα Impairs Stabilization of Synaptic Plasticity and Memory Consolidation

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Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation

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Protein kinase Mζ is necessary and sufficient for LTP maintenance

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Dopaminergic antagonists prevent long-term maintenance of posttetanic LTP in the CA1 region of rat hippocampal slices

1990 • 333 citations

Gene Expression Profiling of Facilitated L-LTP in VP16-CREB Mice Reveals that BDNF Is Critical for the Maintenance of LTP and Its Synaptic Capture

2005 • 323 citations

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The effect of dopaminergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro

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Phosphorylation and modulation of recombinant GluR6 glutamate receptors by cAMP-dependent protein kinase

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Maintenance of long-term potentiation in rat dentate gyrus requires protein synthesis but not messenger RNA synthesis immediately post-tetanization

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Influence of actinomycin D, a RNA synthesis inhibitor, on long‐term potentiation in rat hippocampal neurons in vivo and in vitro.

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Reinforcement of Early Long-Term Potentiation (Early-LTP) in Dentate Gyrus by Stimulation of the Basolateral Amygdala: Heterosynaptic Induction Mechanisms of Late-LTP

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Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus

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Synapse specificity of long-term potentiation breaks down at short distances

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Protein kinase C inhibitors eliminate hippocampal long-term potentiation

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Weak before strong: dissociating synaptic tagging and plasticity-factor accounts of late-LTP

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Maintenance of late-phase LTP is accompanied by PKA-dependent increase in AMPA receptor synthesis

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Synaptic Tagging and Cross-Tagging: The Role of Protein Kinase M in Maintaining Long-Term Potentiation But Not Long-Term Depression

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Protein kinase A inhibitors prevent the maintenance of hippocampal long-term potentiation

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Blockade of norepinephrine-induced long-lasting potentiation in the hippocampal dentate gyrus by an inhibitor of protein synthesis

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Requirement of β‐adrenergic receptor activation and protein synthesis for LTP‐reinforcement by novelty in rat dentate gyrus

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Requirement of Translation But Not Transcription for the Maintenance of Long-Term Depression in the CA1 Region of Freely Moving Rats

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A role for dendritic protein synthesis in hippocampal late LTP

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Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus

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Different Mechanisms and Multiple Stages of LTP

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Plasticity-specific phosphorylation of CaMKII, MAP-kinases and CREB during late-LTP in rat hippocampal slices in vitro

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Differential Role of Mitogen-Activated Protein Kinase in Three Distinct Phases of Memory for Sensitization inAplysia

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Mitogen-Activated Protein Kinase Regulates Early Phosphorylation and Delayed Expression of Ca²⁺/Calmodulin-Dependent Protein Kinase II in Long-Term Potentiation

2001 • 109 citations

Induction and maintenance of late‐phase long‐term potentiation in isolated dendrites of rat hippocampal CA1 pyramidal neurones

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Co-activation of metabotropic glutamate and N-methyl-d-aspartate receptors is involved in mechanisms of long-term potentiation maintenance in rat hippocampal ca1 neurons

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Autonomous activity of CaMKII is only transiently increased following the induction of long‐term potentiation in the rat hippocampus

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Inhibition of protein synthesis in the dentate gyrus, but not the entorhinal cortex, blocks maintenance of long-term potentiation in rats

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Late-phase long-term potentiation: getting to the nucleus

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Protein synthesis-dependent LTP in isolated dendrites of CA1 pyramidal cells

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Heterosynaptic co-activation of glutamatergic and dopaminergic afferents is required to induce persistent long-term potentiation

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Asymptotic hippocampal long-term potentiation in rats does not preclude additional potentiation at later phases

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Modulation by dopamine of population responses and cell membrane properties of hippocampal CA1 neurons in vitro

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Increase in synaptic vesicle proteins accompanies long-term potentiation in the dentate gyrus

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Reinforcement of rat hippocampal LTP by holeboard training

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Homosynaptic and Heterosynaptic Inhibition of Synaptic Tagging and Capture of Long-Term Potentiation by Previous Synaptic Activity

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Capture of the Late Phase of Long-Term Potentiation within and across the Apical and Basilar Dendritic Compartments of CA1 Pyramidal Neurons: Synaptic Tagging Is Compartment Restricted

2006 • 75 citations

Autophosphorylation of αCaMKII is not a general requirement for NMDA receptor‐dependent LTP in the adult mouse

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Resetting of ‘synaptic tags’ is time- and activity-dependent in rat hippocampal CA1in vitro

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The duration of long-term potentiation in the CA1 region of the hippocampal slice preparation

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Mitogen-Activated Protein Kinase-Mediated Reinforcement of Hippocampal Early Long-Term Depression by the Type IV-Specific Phosphodiesterase Inhibitor Rolipram and Its Effect on Synaptic Tagging

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Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG

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A role for protein kinase C in a form of metaplasticity that regulates the induction of long‐term potentiation at CA1 synapses of the adult rat hippocampus

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2-Amino-4-phosphonobutyrate selectively eliminates late phases of long-term potentiation in rat hippocampus

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Time-Dependent Reversal of Long-Term Potentiation in Area CA1 of the Freely Moving Rat Induced by Theta Pulse Stimulation

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Theta frequency stimulation induces a local form of late phase LTP in the CA1 region of the hippocampus

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Metabotropic glutamate receptor subtype agonists facilitate long-term potentiation within a distinct time window in the dentate gyrus in vivo

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An antagonist of the metabotropic glutamate receptor prevents LTP in the dentate gyrus of freely moving rats

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Involvement of multiple phosphatidylinositol 3-kinase-dependent pathways in the persistence of late-phase long term potentiation expression

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An antagonist of glutamate metabotropic receptors, (RS)-α-methyl-4-carboxyphenylglycine, prevents the LTP-related increase in postsynaptic AMPA sensitivity in hippocampal slices

1993 • 49 citations

Cyclic AMP and long-term potentiation in the CA1 region of rat hippocampus

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Drinking after water deprivation prolongs “unsaturated” LTP in the dentate gyrus of rats

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Long-term potentiation at the apical and basal dendritic synapses of CA1 after local stimulation in behaving rats

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receptor activation is required for the induction of both early and late phases of long-term potentiation in rat hippocampal slices

1989 • 42 citations

The amnesic substance 2-deoxy-d-galactose suppresses the maintenance of hippocampal LTP

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Long-term potentiation in the dentate gyrus of the anaesthetized rat is accompanied by an increase in protein efflux into push-pull cannula perfusates

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A comparison of the effects of localized brain administration of catecholamine and protein synthesis inhibitors on memory processing

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Long-Lasting Hippocampal Plasticity: Cellular Model for Memory Consolidation?

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Cellular Mechanisms Of Long-Term Potentiation: Late Maintenance

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Cell Polarity and Subcellular RNA Localization

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The maintenance of hippocampal long-term potentiation is paralleled by a dopamine-dependent increase in glycoprotein fucosylation

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1986 • 23 citations

Emotional and cognitive reinforcement of rat hippocampal long-term potentiation by different learning paradigms

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Long-term potentiation induced changes in protein synthesis of hippocampal subfields of freely moving rats: time-course.

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Transient translocation of protein kinase Cγ in hippocampal long-term potentiation depends on activation of metabotropic glutamate receptors

1999 • 17 citations

Dopamine and macromolecule synthesis in rat hippocampus

1979 • 16 citations

A Multi-Phase Model of Synaptic Long-Term Potentiation in Hippocampal CA1 Neurones: Protein Kinase C Activation and Protein Synthesis Are Required for the Maintenance of the Trace

1988 • 13 citations

Posttetanic Long‐Term Potentiation in Rat Dentate Area Increases Postsynaptic 411B Immunoreactivity

1990 • 9 citations

Long-Term Synaptic Potentiation and Macromolecular Changes in Memory Formation

1988 • 7 citations

Search for a two-input model for future investigations of ‘synaptic tagging’ in freely moving animals in vivo

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Fast increases of AMPA receptor sensitivity following tetanus-induced potentiation in the CA1 region of the rat hippocampus

1997 • 4 citations