Radiation-Induced Modulation of Costimulatory and Coinhibitory T-Cell Signaling Molecules on Human Prostate Carcinoma Cells Promotes Productive Antitumor Immune Interactions

PD-1 and Its Ligands in Tolerance and Immunity

2008 • 4,838 citations

Immunogenic Cell Death in Cancer Therapy

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The PD‐1 pathway in tolerance and autoimmunity

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Antibody therapy of cancer

2012 • 1,988 citations

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2006 • 1,497 citations

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

2012 • 1,274 citations

Local Radiation Therapy of B16 Melanoma Tumors Increases the Generation of Tumor Antigen-Specific Effector Cells That Traffic to the Tumor

2005 • 894 citations

The secret ally: immunostimulation by anticancer drugs

2012 • 642 citations

Sublethal Irradiation of Human Tumor Cells Modulates Phenotype Resulting in Enhanced Killing by Cytotoxic T Lymphocytes

2004 • 532 citations

Generation of Human Cytotoxic T Cells Specific for Human Carcinoembryonic Antigen Epitopes From Patients Immunized With Recombinant Vaccinia-CEA Vaccine

1995 • 506 citations

The significance of OX40 and OX40L to T‐cell biology and immune disease

2009 • 503 citations

Maximizing Tumor Immunity With Fractionated Radiation

2011 • 503 citations

IFN-γ and TNF-α differentially regulate immunomodulation by murine mesenchymal stem cells

2007 • 386 citations

Combining a Recombinant Cancer Vaccine with Standard Definitive Radiotherapy in Patients with Localized Prostate Cancer

2005 • 373 citations

Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

2007 • 353 citations

4-1BB Ligand Induces Cell Division, Sustains Survival, and Enhances Effector Function of CD4 and CD8 T Cells with Similar Efficacy

2001 • 352 citations

Costimulatory and coinhibitory receptors in anti‐tumor immunity

2009 • 269 citations

Expression and Regulation of the PD-L1 Immunoinhibitory Molecule on Microvascular Endothelial Cells

2002 • 256 citations

Signaling Through NK Cell-Associated CD137 Promotes Both Helper Function for CD8+ Cytolytic T Cells and Responsiveness to IL-2 But Not Cytolytic Activity

2002 • 177 citations

Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization

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Standard Treatments Induce Antigen-Specific Immune Responses in Prostate Cancer

2007 • 167 citations

Expression of Costimulatory Ligand CD70 on Steady-State Dendritic Cells Breaks CD8+ T Cell Tolerance and Permits Effective Immunity

2008 • 152 citations

Interferon-γ-induced PD-L1 surface expression on human oral squamous carcinoma via PKD2 signal pathway

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T-Cell Responses to Survivin in Cancer Patients Undergoing Radiation Therapy

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Emerging paradigms of T-cell co-stimulation

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Safety and Immunologic Response of a Viral Vaccine to Prostate-Specific Antigen in Combination with Radiation Therapy when Metronomic-Dose Interleukin 2 Is Used as an Adjuvant

2008 • 110 citations

Suppressed T-cell activation by IFN- -induced expression of PD-L1 on renal tubular epithelial cells

2004 • 101 citations

Development of a Listeria monocytogenes based vaccine against prostate cancer

2008 • 89 citations

The capacity of the TNF family members 4‐1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells

2008 • 89 citations

Radiotherapy augments the immune response to prostate cancer in a time‐dependent manner

2008 • 85 citations

Combination Chemotherapy and Radiation of Human Squamous Cell Carcinoma of the Head and Neck Augments CTL-Mediated Lysis

2006 • 85 citations

Phenotypic stability of a cytotoxic T-cell line directed against an immunodominant epitope of human carcinoembryonic antigen.

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Prostate Cancer Immunotherapy

2011 • 69 citations

Intratumor OX40 stimulation inhibits IRF1 expression and IL‐10 production by Treg cells while enhancing CD40L expression by effector memory T cells

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Combined immunotherapy with Listeria monocytogenes-based PSA vaccine and radiation therapy leads to a therapeutic response in a murine model of prostate cancer

2012 • 34 citations

Role of Immunotherapy for Renal Cell Cancer in 2011

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Innate IFN-γ Is Essential for Programmed Death Ligand-1–Mediated T Cell Stimulation following Listeria monocytogenes Infection

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Combined Immunotherapy with Low-dose IL-2 Plus IFN- for Metastatic Renal Cell Carcinoma: Survival Benefit for Selected Patients with Lung Metastasis and Serum Sodium Level

2011 • 15 citations

Optimizing Prostate Cancer Treatment by Combining Local Radiation Therapy with Systemic Vaccination

2005 • 12 citations