Optimizing Prostate Cancer Treatment by Combining Local Radiation Therapy with Systemic Vaccination

IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity

2001 • 2,658 citations

Tumor Response to Radiotherapy Regulated by Endothelial Cell Apoptosis

2003 • 1,538 citations

Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer

2005 • 940 citations

Sublethal Irradiation of Human Tumor Cells Modulates Phenotype Resulting in Enhanced Killing by Cytotoxic T Lymphocytes

2004 • 532 citations

Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety.

1996 • 521 citations

Radiation and ceramide-induced apoptosis

2003 • 487 citations

Irradiation of Tumor Cells Up-Regulates Fas and Enhances CTL Lytic Activity and CTL Adoptive Immunotherapy

2003 • 452 citations

Applications of pox virus vectors to vaccination: an update.

1996 • 348 citations

Exploiting dendritic cells to improve vaccine efficacy

2002 • 320 citations

A phase I trial of a recombinant vaccinia virus expressing prostate-specific antigen in advanced prostate cancer.

2000 • 300 citations

Phase I Study of Sequential Vaccinations With Fowlpox-CEA(6D)-TRICOM Alone and Sequentially With Vaccinia-CEA(6D)-TRICOM, With and Without Granulocyte-Macrophage Colony-Stimulating Factor, in Patients With Carcinoembryonic Antigen–Expressing Carcinomas

2004 • 298 citations

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation

2004 • 297 citations

A triad of costimulatory molecules synergize to amplify T-cell activation.

1999 • 293 citations

Exploiting dendritic cells to improve vaccine efficacy

2002 • 260 citations

Phase II Randomized Study of Vaccine Treatment of Advanced Prostate Cancer (E7897): A Trial of the Eastern Cooperative Oncology Group

2004 • 252 citations

Phase I study of a vaccine using recombinant vaccinia virus expressing PSA (rV‐PSA) in patients with metastatic androgen‐independent prostate cancer

2002 • 230 citations

Diversified prime and boost protocols using recombinant vaccinia virus and recombinant non-replicating avian pox virus to enhance T-cell immunity and antitumor responses

1997 • 209 citations

Targeting Toll-like Receptor 9 with CpG Oligodeoxynucleotides Enhances Tumor Response to Fractionated Radiotherapy

2005 • 152 citations

Hazard rates for progression after radical prostatectomy for clinically localized prostate cancer

1997 • 134 citations

Molecular mechanisms of ionizing radiation‐induced apoptosis

1999 • 130 citations

A recombinant vaccinia virus expressing human prostate‐specific antigen (PSA): Safety and immunogenicity in a non‐human primate

1995 • 109 citations

Recombinant vaccinia virus vaccine against the human melanoma antigen p97 for use in immunotherapy.

1988 • 98 citations

Enhanced Activation of T Cells by Dendritic Cells Engineered to Hyperexpress a Triad of Costimulatory Molecules

2000 • 97 citations

Admixture of a recombinant vaccinia virus containing the gene for the costimulatory molecule B7 and a recombinant vaccinia virus containing a tumor-associated antigen gene results in enhanced specific T-cell responses and antitumor immunity.

1995 • 93 citations

A recombinant vaccinia virus expressing human carcinoembryonic antigen (CEA)

1991 • 87 citations

Costimulation Enhances the Active Immunotherapy Effect of Recombinant Anticancer Vaccines

1996 • 84 citations

Immunization with type 5 adenovirus recombinant for a tumor antigen in combination with recombinant canarypox virus (alvac) cytokine gene delivery induces destruction of established prostate tumors

2001 • 84 citations

Direct injection of immature dendritic cells into irradiated tumor induces efficient antitumor immunity

2004 • 82 citations

Identification and characterization of a human agonist cytotoxic T-lymphocyte epitope of human prostate-specific antigen.

2002 • 79 citations

Granulocyte-Macrophage Colony Stimulating Factor: An Adjuvant for Cancer Vaccines

2004 • 75 citations

Engineering enhancement of immune responses to DNA-based vaccines in a prostate cancer model in rhesus macaques through the use of cytokine gene adjuvants.

2001 • 60 citations

The role of docetaxel (Taxotere) in neoadjuvant chemotherapy of breast cancer.

1999 • 36 citations

Immunotherapy for prostate cancer

2003 • 32 citations

Approaches to the treatment of patients with hormone-sensitive prostate cancer.

1999 • 19 citations