Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes

2006 • 2,500 citations

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

2006 • 1,499 citations

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

2005 • 1,330 citations

Local Radiation Therapy of B16 Melanoma Tumors Increases the Generation of Tumor Antigen-Specific Effector Cells That Traffic to the Tumor

2005 • 894 citations

Adoptive immunotherapy for cancer: building on success

2006 • 848 citations

Immunotherapy and chemotherapy — a practical partnership

2005 • 639 citations

Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

2001 • 500 citations

Induction of Tumor Cell Apoptosis In Vivo Increases Tumor Antigen Cross-Presentation, Cross-Priming Rather than Cross-Tolerizing Host Tumor-Specific CD8 T Cells

2003 • 441 citations

Cross-presentation by intercellular peptide transfer through gap junctions

2005 • 430 citations

A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer.

2003 • 404 citations

Quantitative Analysis of the Contribution of TCR/pepMHC Affinity and CD8 to T Cell Activation

2003 • 355 citations

Combining radiotherapy and immunotherapy: A revived partnership

2005 • 349 citations

Workshop R: Tumor Immunology, Abstract R1 bis R30

2001 • 312 citations

Bystander elimination of antigen loss variants in established tumors

2004 • 259 citations

Increasing Tumor Antigen Expression Overcomes “Ignorance” to Solid Tumors via Crosspresentation by Bone Marrow-Derived Stromal Cells

2002 • 239 citations

TCRs with high affinity for foreign pMHC show self-reactivity

2002 • 217 citations

Antigenic Cancer Cells Grow Progressively in Immune Hosts without Evidence for T Cell Exhaustion or Systemic Anergy

1997 • 205 citations

A Role for Dipeptidyl Peptidase IV in Suppressing the Malignant Phenotype of Melanocytic Cells

1999 • 191 citations

The role of tumor stroma in the interaction between tumor and immune system

2005 • 179 citations

Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells.

1992 • 169 citations

Tumor Rejection by Disturbing Tumor Stroma Cell Interactions

2001 • 147 citations

Kinetics and thermodynamics of T cell receptor– autoantigen interactions in murine experimental autoimmune encephalomyelitis

2001 • 105 citations

Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells.

2005 • 70 citations

Cancer Immunotherapy and Preclinical Studies: Why We Are Not Wasting Our Time with Animal Experiments

2006 • 53 citations

Ionizing radiation enhances immunogenicity of cells expressing a tumor-specific T-cell epitope

1999 • 30 citations

Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen.

1990 • 28 citations

Tumors with reduced expression of a cytotoxic T lymphocyte recognized antigen lack immunogenicity but retain sensitivity to lysis by cytotoxic T lymphocytes

1993 • 15 citations