Psychotogenicity and N-methyl-D-aspartate receptor antagonism: Implications for neuroprotective pharmacotherapy

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Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels

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gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine

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MK‐801 Fails to Protect Against the Dopaminergic Neuropathology Produced by Systemic 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine in Mice or Intranigral 1‐Methyl‐4‐Phenylpyridinium in Rats

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Therapeutic brain concentration of the NMDA receptor antagonist amantadine

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Comparative Patch‐clamp Studies with Freshly Dissociated Rat Hippocampal and Striatal Neurons on the NMDA Receptor Antagonistic Effects of Amantadine and Memantine

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Amantadine and the glutamate hypothesis of schizophrenia Experiences in the treatment of neuroleptic malignant syndrome

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Amantadine versus Biperiden: A Double-Blind Study of Treatment Efficacy in Neuroleptic Extrapyramidal Movement Disorders

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No difference in the effect of biperiden and amantadine on parkinsonian- and tardive dyskinesia-type involuntary movements: a double-blind crossover, placebo-controlled study in medicated chronic schizophrenic patients.

1995 • 33 citations

The antiparkinsonian drugs budipine and biperiden are use-dependent (uncompetitive) NMDA receptor antagonists

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The antiparkinsonian drug budipine binds to NMDA and sigma receptors in postmortem human brain tissue.

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Clinical Experiences with Budipine in Parkinson Therapy

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Simple and rapid GLC method for the determination of orphenadrine in human plasma

1987 • 18 citations

MK-801 and memantine protect cultured neurons from glutamate toxicity induced by glutamate carboxypeptidase-mediated cleavage of methotrexate

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Neuroprotective effects of memantine

1993 • 2 citations

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