Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 • 4,822 citations

The rat brain: A stereotaxic atlas of the forebrain and lower parts of the brain stem

1986 • 4,155 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

The rat nervous system

1985 • 3,774 citations

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1983 • 2,149 citations

Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous system

1967 • 1,751 citations

The Role of Excitatory Amino Acids and NMDA Receptors in Traumatic Brain Injury

1989 • 1,505 citations

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

1985 • 1,236 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

1984 • 1,007 citations

Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced

1988 • 972 citations

Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin

1987 • 881 citations

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

1984 • 772 citations

The Effect of Deprenyl (Selegiline) on the Natural History of Parkinson's Disease

1989 • 621 citations

Role for Excitatory Amino Acids in Methamphetamine-Induced Nigrostriatal Dopaminergic Toxicity

1989 • 495 citations

Synaptic Activity Mediates Death of Hypoxic Neurons

1983 • 441 citations

Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels

1989 • 347 citations

L-Glutamate has higher affinity than other amino acids for [3H]-D-AP5 binding sites in rat brain membranes

1984 • 293 citations

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

1986 • 267 citations

ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, AND MOTONEURONE DISEASE: ABIOTROPIC INTERACTION BETWEEN AGEING AND ENVIRONMENT?

1986 • 257 citations

IV. Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects

1985 • 210 citations

Beta- N -Methylamino-L-Alanine Neurotoxicity: Requirement for Bicarbonate as a Cofactor

1988 • 199 citations

Kinetics of MK-801 and its effect on quinolinic acid-induced seizures and neurotoxicity in rats.

1989 • 164 citations

NEUROLOGICAL DISEASE IN BOXERS

1963 • 160 citations

Anti-parkinsonian agents are phencyclidine agonists and N-methyl-aspartate antagonists

1987 • 117 citations

1-Methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway

1986 • 111 citations

Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+

1988 • 82 citations

Uptake of a novel anticonvulsant compound, 2-amino-7-phosphono-[4,5-3H]Heptanoic acid, into mouse brain

1983 • 35 citations

The biodisposition of MPP+ in mouse brain

1989 • 29 citations

The histological effects of intracerebral injection or infusion of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and MPP+ (1-methyl-4-phenylpyridinium) in rat and mouse

1988 • 23 citations

Determination of the pharmacokinetics of 2-amino-7-phosphonoheptanoate in rat plasma and cerebrospinal fluid

1988 • 11 citations

Ultrastructural alterations induced by 1-methyl-4-phenylpyridinium (MPP+) in canine substantia nigra and rat mesencephalon in vitro

1989 • 11 citations

Uptake of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and the N-methyl-4-phenylpyridinium ion (MPP+) into fetal mouse brain through the placenta

1989 • 11 citations