3-nitropropionic acid is an indirect excitotoxin to cultured cerebellar granule neurons

Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced

1988 • 972 citations

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1992 • 964 citations

3-Nitropropionic Acid - Exogenous Animal Neurotoxin and Possible Human Striatal Toxin

1991 • 476 citations

3-Nitropropionate, the toxic substance of Indigofera , is a suicide inactivator of succinate dehydrogenase

1977 • 371 citations

Age‐Dependent Vulnerability of the Striatum to the Mitochondrial Toxin 3‐Nitropropionic Acid

1993 • 360 citations

Actions of ketamine, phencyclidine and MK‐801 on NMDA receptor currents in cultured mouse hippocampal neurones.

1991 • 278 citations

Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: A type of hypoxic (energy deficient) brain damage

1987 • 229 citations

N-methyl-D-aspartate receptor-mediated neuroprotection in cerebellar granule cells requires new RNA and protein synthesis.

1992 • 167 citations

Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition.

1991 • 157 citations

The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells

1990 • 140 citations

BASAL GANGLIA DEGENERATION, MYELIN ALTERATIONS, AND ENZYME INHIBITION INDUCED IN MICE BY THE PLANT TOXIN 3‐NITROPROPANOIC ACID

1982 • 121 citations

Inhibition of energy metabolism by 3-nitropropionic acid activates ATP-sensitive potassium channels

1992 • 90 citations

N-methyl-D-aspartate exposure blocks glutamate toxicity in cultured cerebellar granule cells.

1992 • 81 citations

NMDA receptor-mediated glutamate toxicity of cultured cerebellar, cortical and mesencephalic neurons: neuroprotective properties of amantadine and memantine

1993 • 78 citations

Correlation of morphologic brain lesions with physiologic alterations and blood-brain barrier impairment in 3-intropropionic acid toxicity in rats

1987 • 69 citations

Brain enzyme and clinical alterations induced in rats and mice by nitroaliphatic toxicants

1985 • 62 citations

Niacinamide blocks 3-acetylpyridine toxicity of cerebellar granule cells in vitro

1992 • 34 citations