The antiparkinsonian agent budipine is an N-methyl-D-aspartate antagonist

Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists

1988 • 1,202 citations

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1991 • 554 citations

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1989 • 426 citations

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.

1988 • 302 citations

NMDA antagonists potentiate antiparkinsonian actions of <scp>L</scp>‐dopa in monoamine‐depleted rats

1990 • 285 citations

Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats

1989 • 168 citations

Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-Dopa in models of Parkinson's disease

1991 • 135 citations

Modulation of the seizure threshold for excitatory amino acids in mice by antiepileptic drugs and chemoconvulsants.

1993 • 64 citations

Differential effects of the excitatory amino acid antagonists, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 3-((±)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), on spinal reflex activity in mice

1990 • 43 citations

Adjuvant treatment of Parkinson's disease with budipine: a double-blind trial versus placebo

1987 • 32 citations

Intracerebroventricular administration of 1-methyl-4-phenylpyridinium ion in mice: Effects of simultaneously administered nomifensine, deprenyl, and 1-t-butyl-4,4-diphenylpiperidine

1988 • 25 citations

Clinical Experiences with Budipine in Parkinson Therapy

1985 • 20 citations

[Summarizing description of the pharmacology of budipine, a new 4,4-diphenylpiperidine derivative used in Parkinson therapy (author's transl)].

1982 • 19 citations

Pharmacokinetics and Metabolism of Budipine in Animals and Humans

1985 • 13 citations

[Modification of Parkinson tremor by budipine. A comparative study with amantadine].

1986 • 9 citations

Biochemical and Pharmacologic Aspects of the Mechanism of Action of Budipine

1985 • 9 citations

Budipine: A New Chemical Substance in the Treatment of Parkinson’s Disease

1985 • 9 citations

The Pharmacodynamics of Budipine on Central Neurotransmitter Systems

1985 • 9 citations

Pharmacologic Bases of Antiparkinsonian Therapy

1985 • 7 citations