β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Glutamate neurotoxicity in cortical cell culture

1987 • 1,400 citations

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

1987 • 1,280 citations

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 • 1,098 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

1985 • 1,025 citations

Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists

1988 • 983 citations

Neurotoxicity of a Fragment of the Amyloid Precursor Associated with Alzheimer's Disease

1989 • 904 citations

Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin

1987 • 881 citations

Glutamate neurotoxicity in cortical cell culture is calcium dependent

1985 • 818 citations

Alzheimer's Disease

1986 • 772 citations

Agonists and antagonists for excitatory amino acid receptors

1987 • 692 citations

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

1985 • 634 citations

Amyloid β Protein Enhances the Survival of Hippocampal Neurons in Vitro

1989 • 470 citations

Calcium regulation of neurite elongation and growth cone motility

1987 • 423 citations

Glutamate dysfunction in Alzheimer's disease: an hypothesis

1987 • 335 citations

Vulnerability of cultured cortical neurons to damage by excitotoxins: differential susceptibility of neurons containing NADPH-diaphorase

1988 • 309 citations

Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration

1986 • 204 citations

Localization of voltage-sensitive calcium channels along developing neurites: Their possible role in regulating neurite elongation

1982 • 202 citations

β-Amyloid protein promotes neuritic branching in hippocampal cultures

1990 • 188 citations

Controlled induction of paired helical filaments of the Alzheimer type in cultured human neurons, by glutamate and aspartate

1985 • 128 citations

Correlation between senile plaque and neurofibrillary tangle counts in cerebral cortex and neuronal counts in cortex and subcortical structures in Alzheimer's disease

1985 • 127 citations

Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence.

1987 • 98 citations

An appraisal of the neurotoxicity of cycad and the etiology of amyotrophic lateral sclerosis on Guam.

1972 • 60 citations