Migratory Activity and Functional Changes of Green Fluorescent Effector Cells before and during Experimental Autoimmune Encephalomyelitis

B lymphocytes secrete antigen-presenting vesicles.

1996 • 3,198 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

T‐lymphocyte entry into the central nervous system

1991 • 1,168 citations

A safe packaging line for gene transfer: separating viral genes on two different plasmids

1988 • 1,118 citations

The Role of Chemokine Receptors in Primary, Effector, and Memory Immune Responses

2000 • 1,077 citations

Molecular Characterization of Dendritic Cell-Derived Exosomes

1999 • 1,005 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1981 • 917 citations

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

Cellular immune reactivity within the CNS

1986 • 771 citations

Selecting and maintaining a diverse T-cell repertoire

1999 • 712 citations

Resistance to Experimental Autoimmune Encephalomyelitis in Mice Lacking the Cc Chemokine Receptor (Ccr2)

2000 • 580 citations

Cc Chemokine Receptor 2 Is Critical for Induction of Experimental Autoimmune Encephalomyelitis

2000 • 510 citations

TCR-Mediated Internalization of Peptide-MHC Complexes Acquired by T Cells

1999 • 456 citations

Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential.

1993 • 442 citations

From TCR Engagement to T Cell Activation

1999 • 379 citations

Migration of Hematogenous Cells Through the Blood‐Brain Barrier and the Initiation of CNS Inflammation

1991 • 362 citations

Chemokines in the CNS: plurifunctional mediators in diverse states

1999 • 345 citations

Checkpoints in the progression of autoimmune disease: lessons from diabetes models.

1996 • 340 citations

Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain.

1993 • 305 citations

Homeostatic T Cell Proliferation

2000 • 279 citations

Animal models

1994 • 276 citations

A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry.

1996 • 224 citations

Experimental autoimmune encephalomyelitis: the antigen specificity of T lymphocytes determines the topography of lesions in the central and peripheral nervous system.

1997 • 190 citations

Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia.

1994 • 186 citations

Class II MHC/Peptide Complexes Are Released from APC and Are Acquired by T Cell Responders During Specific Antigen Recognition

1999 • 154 citations

OX-40: life beyond the effector T cell stage

1998 • 152 citations

Gene transfer into CD4+ T lymphocytes: Green fluorescent protein-engineered, encephalitogenic T cells illuminate brain autoimmune responses

1999 • 151 citations

T-Cell Apoptosis in Inflammatory Brain Lesions

1998 • 146 citations

Role of Ox40 Signals in Coordinating Cd4 T Cell Selection, Migration, and Cytokine Differentiation in T Helper (Th)1 and Th2 Cells

2000 • 143 citations

OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand

1996 • 138 citations

AIDS and the brain: is there a chemokine connection?

1999 • 135 citations

Neuronal FasL Induces Cell Death of Encephalitogenic T Lymphocytes

2000 • 122 citations

Apoptotic elimination of Vβ8.2⁺ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of Vβ8.2⁺ encephalitogenic T cells

1994 • 113 citations

[31] Myelin basic proteins

1974 • 111 citations

Myelin Basic Protein

1981 • 94 citations

Experimental autoimmune encephalomyelitis as a model of immune-mediated CNS disease

1993 • 82 citations

Antigen presentation by T cells: T cell receptor ligation promotes antigen acquisition from professional antigen‐presenting cells

1997 • 74 citations

T cells in the lesion of experimental autoimmune encephalomyelitis. Enrichment for reactivities to myelin basic protein and to heat shock proteins.

1992 • 68 citations

Antigen-specific down-regulation of myelin basic protein-reactive T cells during spontaneous recovery from experimental autoimmune encephalomyelitis: further evidence of apoptotic deletion of autoreactive T cells in the central nervous system

1995 • 64 citations

Preferential distribution of Vβ 8.2‐positive T cells in the central nervous system of rats with myelin basic protein‐induced autoimmune encephalomyelitis

1993 • 61 citations

AIDS and the brain

1986 • 50 citations

Expression of major histocompatibility complex class II molecules in rat T cells

1994 • 46 citations

Adoptive transfer of murine chronic-relapsing autoimmune encephalomyelitis

1987 • 44 citations

Hypothesis: Antigen-specific T cells prime central nervous system endothelium for recruitment of nonspecific inflammatory cells to effect autoimmune demyelination

1991 • 44 citations

Activated rat T cells synthesize and express functional major histocompatibility class II antigens.

1995 • 40 citations

TCR V gene usage in autoimmunity

1994 • 39 citations

Synthesis and cell surface display of class II determinants by long‐term propagated rat T line cells

1987 • 27 citations

Homing of antigen-specific T cells in the Lewis rat. I. Accumulation of antigen-reactive cells in the perithymic lymph nodes.

1987 • 15 citations

Effects of cytokines and glucocorticoids on endogenous class II MHC antigen expression by activated rat CD4⁺ T cells. Mature CD4⁺CD8⁻thymocytes are phenotypically heterogeneous on activation

1996 • 12 citations

Experimental Autoimmune Encephalomyelitis

1983 • 4 citations

Experimental Autoimmune Encephalomyelitis

1998 • 4 citations