Cc Chemokine Receptor 2 Is Critical for Induction of Experimental Autoimmune Encephalomyelitis

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1997 • 1,964 citations

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1992 • 1,711 citations

T‐lymphocyte entry into the central nervous system

1991 • 1,168 citations

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.

1997 • 1,078 citations

Defects in Macrophage Recruitment and Host Defense in Mice Lacking the CCR2 Chemokine Receptor

1997 • 700 citations

Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

1997 • 671 citations

Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared.

1995 • 622 citations

Astrocyte expression of mRNA encoding cytokines IP‐10 and JE/MCP‐1 in experimental autoimmune encephalomyelitis

1993 • 496 citations

Chemokines and T Lymphocytes

1998 • 403 citations

Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives

1997 • 365 citations

Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice

1999 • 340 citations

Antibodies to CD44 and integrin α₄, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment

1999 • 287 citations

Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1α and monocyte chemotactic protein-1

1998 • 241 citations

Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis.

1990 • 234 citations

Chemokine regulation of experimental autoimmune encephalomyelitis: temporal and spatial expression patterns govern disease pathogenesis.

1998 • 229 citations

Monocyte Chemoattractant Protein-1 Mediates Cockroach Allergen-Induced Bronchial Hyperreactivity in Normal But Not CCR2−/− Mice: The Role of Mast Cells

1999 • 210 citations

Cutting Edge Commentary: Chemokine Regulation of Experimental Autoimmune Encephalomyelitis: Temporal and Spatial Expression Patterns Govern Disease Pathogenesis

1998 • 182 citations

Defects in the generation of IFN-gamma are overcome to control infection with Leishmania donovani in CC chemokine receptor (CCR) 5-, macrophage inflammatory protein-1 alpha-, or CCR2-deficient mice.

1999 • 163 citations

Defects in the Generation of IFN-γ Are Overcome to Control Infection withLeishmania donovaniin CC Chemokine Receptor (CCR) 5-, Macrophage Inflammatory Protein-1α-, or CCR2-Deficient Mice

1999 • 131 citations

Cloning and Functional Expression of mCCR2, a Murine Receptor for the C-C Chemokines JE and FIC

1996 • 128 citations

Effect of C-C Chemokine Receptor 2 (CCR2) Knockout on Type-2 (Schistosomal Antigen-Elicited) Pulmonary Granuloma Formation

1999 • 112 citations

The central nervous system environment controls effector CD4⁺ T cell cytokine profile in experimental allergic encephalomyelitis

1997 • 106 citations

Murine Astrocytes Express a Functional Chemokine Receptor

1997 • 82 citations

Anergy in vivo: down-regulation of antigen-specific CD4⁺ T_h1 but not T_h2 cytokine responses

1994 • 79 citations

Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease

1999 • 74 citations

Antibodies against Leukocyte Function-Associated Antigen-1 and against Intercellular Adhesion Molecule-1 Together Suppress the Progression of Experimental Allergic Encephalomyelitis

1995 • 56 citations

Partial inhibition of AT-EAE by an antibody to ICAM-1: Clinico-histological and MRI studies

1996 • 37 citations

Induction of experimental autoimmune encephalomyelitis in severe combined immunodeficient mice reconstituted with allogeneic or xenogeneic hematopoietic cells.

1993 • 25 citations