B lymphocytes secrete antigen-presenting vesicles.

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes.

1983 • 1,586 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes.

1985 • 1,153 citations

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat.

1991 • 874 citations

Assembly, Transport, and Function of MHC Class II Molecules

1994 • 791 citations

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes.

1991 • 693 citations

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

1995 • 684 citations

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1991 • 663 citations

Role of Lymphocyte Adhesion Receptors in Transient Interactions and Cell Locomotion

1991 • 532 citations

Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

1990 • 452 citations

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

1990 • 445 citations

Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes

1994 • 442 citations

Movement of internalized ligand–receptor complexes along a continuous endosomal reticulum

1990 • 428 citations

Isolation and characterization of the intracellular MHC class II compartment

1994 • 426 citations

Endocytosis and intracellular processing of transferrin and colloidal gold-transferrin in rat reticulocytes: demonstration of a pathway for receptor shedding.

1984 • 397 citations

CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells.

1991 • 390 citations

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

1994 • 349 citations

Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan.

1988 • 335 citations

Selection of a human T helper type 1-like T cell subset by mycobacteria.

1991 • 281 citations

How MHC Class II Molecules Acquire Peptide Cargo: Biosynthesis and Trafficking through the Endocytic Pathway

1995 • 280 citations

A role for peptide in determining MHC class II structure

1991 • 275 citations

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

1994 • 244 citations

Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules.

1991 • 234 citations

Separation of subcellular compartments containing distinct functional forms of MHC class II.

1994 • 221 citations

Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization.

1993 • 221 citations

Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes.

1992 • 219 citations

Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells.

1995 • 185 citations

Differential expression and serologically distinct subpopulations of human Ia antigens detected with monoclonal antibodies to Ia alpha and beta chains

1982 • 183 citations

Novel pathways of antigen presentation for the maintenance of memory

1991 • 173 citations

How MHC class II molecules reach the endocytic pathway.

1995 • 173 citations

Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells.

1992 • 167 citations

Multivesicular bodies in HEp-2 cells are maturing endosomes.

1993 • 154 citations

Antigenic relatedness of a strongly immunogenic 65 kDA mycobacterial protein antigen with a similarly sized ubiquitous bacterial common antigen

1988 • 152 citations

Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes.

1995 • 130 citations

Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment.

1993 • 124 citations

MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells.

1995 • 122 citations

Mycobacterium leprae-specific protein antigens defined by cloned human helper T cells

1986 • 117 citations

Relations between the intracellular pathways of the receptors for transferrin, asialoglycoprotein, and mannose 6-phosphate in human hepatoma cells.

1989 • 110 citations

Specificity of monoclonal antibodies directed against human and murine class II histocompatibility antigens as analyzed by binding to HLA-deletion mutant cell lines

1985 • 106 citations

IA mutant functional antigen-presenting cell lines.

1983 • 100 citations

A new model for lethal hit delivery by cytotoxic T lymphocytes

1990 • 96 citations

Transport and intracellular distribution of MHC class II molecules and associated invariant chain in normal and antigen-processing mutant cell lines.

1994 • 77 citations

I-Kk and H-2Kk antigens are shed as supramolecular particles in association with membrane lipids.

1981 • 69 citations

Human Resident Langerhans Cells Display a Lysosomal compartment Enriched in MHC Class II

1994 • 68 citations

Characterization of Ia Antigens in Mouse Serum

1976 • 45 citations

Turnover and Shedding of Ia Antigens by Murine Spleen Cells in Culture

1979 • 45 citations

Antigen processing and intracellular traffic of antigens and MHC molecules

1993 • 41 citations

Release of Ia antigens by a cultured B cell line.

1980 • 40 citations

Assembly, Transport, and Function of MHC Class II Molecules

1994 • 34 citations

Role Of Lymphocyte Adhesion Receptors In Transient Interactions And Cell Locomotion

1991 • 32 citations

Identification and characterization of a T cell-inducing epitope of bovine ribonuclease that can be restricted by multiple class II molecules.

1991 • 31 citations

How MHC Class II Molecules Acquire Peptide Cargo: Biosynthesis and Trafficking Through the Endocytic Pathway

1995 • 15 citations

EJCB-Lecture. A novel lysosomal compartment engaged in antigen presentation.

1994 • 15 citations

Chapter 17: Techniques for Studying Phagocytic Processing of Bacteria for Class I or II MHC-Restricted Antigen Recognition by T Lymphocytes

1995 • 14 citations

Deleted Work

1955 • 0 citations