Prediction of Novel Bag-1 Homologs Based on Structure/Function Analysis Identifies Snl1p as an Hsp70 Co-chaperone in Saccharomyces cerevisiae

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

1995 • 5,246 citations

[26] Raster3D: Photorealistic molecular graphics

1997 • 3,784 citations

Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein

2002 • 3,280 citations

The Hsp70 and Hsp60 Chaperone Machines

1998 • 2,793 citations

Genomic Libraries and a Host Strain Designed for Highly Efficient Two-Hybrid Selection in Yeast

1996 • 2,631 citations

Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

1995 • 1,943 citations

The Yeast Nuclear Pore Complex

2000 • 1,383 citations

Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK

1996 • 1,247 citations

Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity

1995 • 863 citations

Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK.

1991 • 835 citations

Further additions to MolScript version 1.4, including reading and contouring of electron-density maps

1999 • 763 citations

Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly

1989 • 763 citations

The ATP hydrolysis-dependent reaction cycle of the Escherichia coli Hsp70 system DnaK, DnaJ, and GrpE.

1994 • 520 citations

BAG-1 modulates the chaperone activity of Hsp70/Hsc70

1997 • 511 citations

An Evolutionarily Conserved Family of Hsp70/Hsc70 Molecular Chaperone Regulators

1999 • 509 citations

Crystal Structure of the Nucleotide Exchange Factor GrpE Bound to the ATPase Domain of the Molecular Chaperone DnaK

1997 • 489 citations

ConSurf: an algorithmic tool for the identification of functional regions in proteins by surface mapping of phylogenetic information

2001 • 481 citations

The Ubiquitin-related BAG-1 Provides a Link between the Molecular Chaperones Hsc70/Hsp70 and the Proteasome

2000 • 478 citations

Kinetics of Molecular Chaperone Action

1994 • 440 citations

Structure of a Bag/Hsc70 Complex: Convergent Functional Evolution of Hsp70 Nucleotide Exchange Factors

2001 • 427 citations

Getting Newly Synthesized Proteins into Shape

2000 • 426 citations

GrpE-like regulation of the Hsc70 chaperone by the anti-apoptotic protein BAG-1

1997 • 397 citations

Molecular chaperone targeting and regulation by BAG family proteins

2001 • 390 citations

The Role of ATP in the Functional Cycle of the DnaK Chaperone System

1995 • 388 citations

ATP-induced protein Hsp70 complex dissociation requires K+ but not ATP hydrolysis

1993 • 366 citations

Regulation of the Heat-shock Protein 70 Reaction Cycle by the Mammalian DnaJ Homolog, Hsp40

1996 • 323 citations

Regulation of Hsp70 function by a eukaryotic DnaJ homolog.

1992 • 262 citations

A new family of yeast nuclear pore complex proteins.

1992 • 256 citations

Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23

2000 • 230 citations

The molecular chaperone Ssb from Saccharomyces cerevisiae is a component of the ribosome–nascent chain complex

1998 • 224 citations

A Bipartite Signaling Mechanism Involved in DnaJ-mediated Activation of the Escherichia coli DnaK Protein

1996 • 222 citations

Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange.

2001 • 220 citations

The Second Step of ATP Binding to DnaK Induces Peptide Release

1996 • 219 citations

Structural insights into substrate binding by the molecular chaperone DnaK.

2000 • 190 citations

BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release

1998 • 179 citations

A new subclass of nucleoporins that functionally interact with nuclear pore protein NSP1.

1992 • 172 citations

GrpE Accelerates Nucleotide Exchange of the Molecular Chaperone DnaK with an Associative Displacement Mechanism

1997 • 171 citations

Mammalian protein RAP46: an interaction partner and modulator of 70kDa heat shock proteins

1997 • 157 citations

Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein.

2001 • 149 citations

Bag1 Functions In Vivo as a Negative Regulator of Hsp70 Chaperone Activity

2000 • 137 citations

Nup116p and Nup100p are interchangeable through a conserved motif which constitutes a docking site for the mRNA transport factor Gle2p

1998 • 136 citations

Modulation of the ATPase Activity of the Molecular Chaperone DnaK by Peptides and the DnaJ and GrpE Heat Shock Proteins

1995 • 133 citations

Human DnaJ Homologs dj2 and dj3, and bag-1 Are Positive Cochaperones of hsc70

2000 • 121 citations

Samui, a novel cold‐inducible gene, encoding a protein with a BAG domain similar to silencer of death domains (SODD/BAG‐4), isolated from Bombyx diapause eggs

2001 • 90 citations

The hsp70-associating protein Hap46 binds to DNA and stimulates transcription

1999 • 82 citations

The cold sensitivity of a mutant of Saccharomyces cerevisiae lacking a mitochondrial heat shock protein 70 is suppressed by loss of mitochondrial DNA.

1996 • 80 citations

The biochemical properties of the ATPase activity of a 70-kDa heat shock protein (Hsp70) are governed by the C-terminal domains

1998 • 79 citations

ATPase kinetics of recombinant bovine 70 kDa heat shock cognate protein and its amino-terminal ATPase domain

1994 • 64 citations

Nup116p Associates with the Nup82p-Nsp1p-Nup159p Nucleoporin Complex

2000 • 55 citations

Assembly and Preferential Localization of Nup116p on the Cytoplasmic Face of the Nuclear Pore Complex by Interaction with Nup82p

2000 • 47 citations

The Integral Membrane Protein Snl1p Is Genetically Linked to Yeast Nuclear Pore Complex Function

1998 • 46 citations

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