BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

Interaction of Hsp 70 with Newly Synthesized Proteins: Implications for Protein Folding and Assembly

1990 • 1,293 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Successive action of DnaK, DnaJ and GroEL along the pathway of chaperone-mediated protein folding

1992 • 965 citations

A Role for a 70-Kilodalton Heat Shock Protein in Lysosomal Degradation of Intracellular Proteins

1989 • 932 citations

Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity

1995 • 863 citations

Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries

1997 • 797 citations

Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP

1993 • 650 citations

The translation machinery and 70 kd heat shock protein cooperate in protein synthesis

1992 • 512 citations

BAG-1 modulates the chaperone activity of Hsp70/Hsc70

1997 • 511 citations

Role of auxilin in uncoating clathrin-coated vesicles

1995 • 495 citations

Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle

1995 • 436 citations

Identification of a regulatory motif in Hsp70 that affects ATPase activity, substrate binding and interaction with HDJ-1.

1995 • 428 citations

The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding.

1996 • 424 citations

The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner

1990 • 407 citations

GrpE-like regulation of the Hsc70 chaperone by the anti-apoptotic protein BAG-1

1997 • 397 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Interaction of Hsp70 chaperones with substrates

1997 • 372 citations

Molecular Chaperone Machines: Chaperone Activities of the Cyclophilin Cyp-40 and the Steroid Aporeceptor-Associated Protein p23

1996 • 371 citations

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1.

1996 • 364 citations

The transport of proteins into the nucleus requires the 70-kilodalton heat shock protein or its cytosolic cognate.

1992 • 335 citations

Interaction of hsp70 with unfolded proteins: effects of temperature and nucleotides on the kinetics of binding.

1991 • 332 citations

Regulation of the Heat-shock Protein 70 Reaction Cycle by the Mammalian DnaJ Homolog, Hsp40

1996 • 323 citations

HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death.

1996 • 318 citations

The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles.

1985 • 301 citations

Ubiquitin-dependent Degradation of Certain Protein Substrates in Vitro Requires the Molecular Chaperone Hsc70

1997 • 294 citations

Common and divergent peptide binding specificities of hsp70 molecular chaperones.

1994 • 283 citations

Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70.

1993 • 266 citations

The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein

1991 • 245 citations

The Amino-Terminal Transforming Region of Simian Virus 40 Large T and Small t Antigens Functions as a J Domain

1997 • 226 citations

A Bipartite Signaling Mechanism Involved in DnaJ-mediated Activation of the Escherichia coli DnaK Protein

1996 • 222 citations

p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1

1998 • 203 citations

BAG-1L Protein Enhances Androgen Receptor Function

1998 • 195 citations

Heat-induced Chaperone Activity of HSP90

1996 • 194 citations

Mammalian protein RAP46: an interaction partner and modulator of 70kDa heat shock proteins

1997 • 157 citations

The J Domain of Simian Virus 40 Large T Antigen Is Required To Functionally Inactivate RB Family Proteins

1998 • 149 citations

RAP46 Is a Negative Regulator of Glucocorticoid Receptor Action and Hormone-induced Apoptosis

1998 • 144 citations

Unfolded proteins stimulate molecular chaperone Hsc70 ATPase by accelerating ADP/ATP exchange

1992 • 132 citations

Interaction of BAG-1 with Retinoic Acid Receptor and Its Inhibition of Retinoic Acid-induced Apoptosis in Cancer Cells

1998 • 131 citations

BiP Binding Sequences in Antibodies

1995 • 113 citations

Proteins interacting with the molecular chaperone hsp70/hsc70: physical associations and effects on refolding activity

1997 • 108 citations

Molecular cloning of human p48, a transient component of progesterone receptor complexes and an Hsp70-binding protein.

1996 • 108 citations

The molecular chaperone hsp40 regulates the activity of P58 ^IPK , the cellular inhibitor of PKR

1997 • 103 citations

Association of a cellular heat shock protein with simian virus 40 large T antigen in transformed cells

1989 • 99 citations

The Transport of Proteins into the Nucleus Requires the 70-Kilodalton Heat Shock Protein or Its Cytosolic Cognate

1992 • 92 citations

Conserved ATPase and luciferase refolding activities between bacteria and yeast Hsp70 chaperones and modulators

1995 • 72 citations

ATPase kinetics of recombinant bovine 70 kDa heat shock cognate protein and its amino-terminal ATPase domain

1994 • 64 citations

Interaction of Auxilin with the Molecular Chaperone, Hsc70

1997 • 60 citations

Identification of a 60-Kilodalton Stress-Related Protein, p60, which Interacts with hsp90 and hsp70

1993 • 48 citations