Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

hnRNP PROTEINS AND THE BIOGENESIS OF mRNA

1993 • 1,486 citations

SR proteins: a conserved family of pre-mRNA splicing factors.

1992 • 766 citations

Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2

1992 • 724 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

1984 • 679 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

1991 • 508 citations

A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro

1990 • 500 citations

The essential pre-mRNA splicing factor SF2 influences 5′ splice site selection by activating proximal sites

1990 • 454 citations

Distinct Functions of SR Proteins in Alternative pre-mRNA Splicing

1993 • 407 citations

Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses

1979 • 395 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA

1993 • 332 citations

A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells

1990 • 313 citations

General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer.

1993 • 286 citations

Mechanisms for selecting 5′ splice sites in mammalian pre-mRNA splicing

1994 • 261 citations

cis and trans activation of globin gene transcription in transient assays.

1983 • 257 citations

Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35

1992 • 244 citations

Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF.

1993 • 241 citations

General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection.

1992 • 241 citations

Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts

1985 • 229 citations

The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.

1994 • 186 citations

Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells.

1986 • 161 citations

Differential splicing yields novel adenovirus 5 E1A mRNAs that encode 30 kd and 35 kd proteins.

1987 • 142 citations

Alternative splicing of tropomyosin pre-mRNAs in vitro and in vivo.

1988 • 115 citations

Alternative splicing of beta-tropomyosin pre-mRNA: cis-acting elements and cellular factors that block the use of a skeletal muscle exon in nonmuscle cells.

1991 • 98 citations

The Drosophila RNA-binding protein RBP1 is localized to transcriptionally active sites of chromosomes and shows a functional similarity to human splicing factor ASF/SF2.

1992 • 90 citations

A potential splicing factor is encoded by the opposite strand of the trans-spliced c-myb exon.

1992 • 89 citations

Splicing of adenovirus 2 early region 1A mRNAs is non-sequential

1983 • 83 citations

A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs

1991 • 77 citations

Clathrin light chain B: gene structure and neuron-specific splicing

1992 • 41 citations

Cis-elements involved in alternative splicing in the rat β-tropomyosin gene: the 3′-splice site of the skeletal muscle exon 7 is the major site of blockage in nonmuscle cells

1993 • 24 citations