The essential pre-mRNA splicing factor SF2 influences 5′ splice site selection by activating proximal sites

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation

1986 • 755 citations

ALTERNATIVE SPLICING IN THE CONTROL OF GENE EXPRESSION

1989 • 701 citations

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

1984 • 679 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts.

1988 • 539 citations

Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA

1987 • 508 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro

1990 • 500 citations

A role for exon sequences and splice-site proximity in splice-site selection

1986 • 494 citations

Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for Pre-mRNA splicing in vitro

1985 • 442 citations

Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA

1986 • 389 citations

A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5′ cleavage site.

1988 • 364 citations

Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells.

1990 • 359 citations

Alternative splicing of human dystrophin mRNA generates isoforms at the carboxy terminus

1989 • 332 citations

Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing.

1989 • 314 citations

5' splice site selection in yeast: genetic alterations in base-pairing with U1 reveal additional requirements.

1988 • 307 citations

Functions of the Abundant U-snRNPs

1988 • 284 citations

A compensatory base change in human U2 snRNA can suppress a branch site mutation.

1989 • 284 citations

Effects of RNA secondary structure on alternative splicing of Pre-mRNA: Is folding limited to a region behind the transcribing RNA polymerase?

1988 • 280 citations

Alternative splicing caused by RNA secondary structure

1985 • 274 citations

Signals for the selection of a splice site in pre-mRNA

1987 • 247 citations

Structure and function of major and minor small nuclear ribonucleoprotein particles

1989 • 242 citations

The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemia.

1987 • 179 citations

The role of nucleotide sequences in splice site selection in eukaryotic pre-messenger RNA

1986 • 148 citations

Amount of RNA secondary structure required to induce an alternative splice.

1987 • 128 citations

Alternative splicing of tropomyosin pre-mRNAs in vitro and in vivo.

1988 • 115 citations

The 5′ splice site: phylogetic evalution and variable geometry of association with U1RNA

1989 • 113 citations

Precision and orderliness in splicing

1987 • 104 citations

Hierarchy for 5′ splice site preference determined in vivo

1990 • 87 citations

Alternative splicing of E1A transcripts of adenovirus requires appropriate ionic conditions in vitro

1987 • 77 citations

A secondary structure at the 3′ splice site affects thein vitrosplicing reaction of mouse immunoglobulin μ chain pre-mRNAs

1989 • 73 citations

The 216-nucleotide intron of the E1A pre-mRNA contains a hairpin structure that permits utilization of unusually distant branch acceptors.

1989 • 73 citations

Amount of RNA Secondary Structure Required to Induce an Alternative Splice

1987 • 59 citations

Specific accessory sequences in Saccharomyces cerevisiae introns control assembly of pre-mRNAs into spliceosomes.

1987 • 49 citations

Statistical analysis of mammalian pre-mRNA splicing sites

1989 • 41 citations

Short donor site sequences inserted within the intron of beta-globin pre-mRNA serve for splicing in vitro.

1988 • 36 citations

In vitrosplicing of mRNA precursors: 5' cleavage site can be predicted from the interaction between the 5' splice region and the 5' terminus of U1 snRNA

1988 • 32 citations

Impairment of yeast pre-mRNA splicing by potential secondary structure-forming sequences near the conserved branchpoint sequence

1988 • 26 citations

A U1 Small Nuclear Ribonucleoprotein Particle with Altered Specificity Induces Alternative Splicing of an Adenovirus E1A mRNA Precursor

1989 • 22 citations

Splice site consensus sequences are preferentially accessible to nucleases in isolated adenovirus RNA

1986 • 15 citations

Categorical discriminant analysis of 3′-splice site signals of mRNA precursors in higher eukaryote genes

1988 • 11 citations

Splice-Site Signals of mRNA Precursors as Revealed by Computer Search. Site-Specific Mutagenesis and Thalassemia

1985 • 11 citations

Structures of human and rabbit .beta.-globin precursor messenger RNAs in solution

1989 • 7 citations