Prognostic value of tumour associated antigen immunoreactivity and apoptosis in cerebral glioblastomas: an analysis of 168 cases

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Regression Models and Life-Tables

1992 • 27,454 citations

Regression Models and Life-Tables

1972 • 27,145 citations

Nonparametric Estimation from Incomplete Observations

1958 • 7,673 citations

Regression Trees for Censored Data

1988 • 497 citations

A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis.

1996 • 407 citations

Patient age, histologic features, and length of survival in patients with glioblastoma multiforme

1987 • 388 citations

Subsets of Glioblastoma Multiforme Defined by Molecular Genetic Analysis

1993 • 334 citations

Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumours

1992 • 264 citations

Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification.

1994 • 255 citations

A Study of Apoptosis in Normal and Pathologic Nervous Tissue After In situ End-Labeling of DNA Strand Breaks

1994 • 205 citations

Prognostic value of the expression of p53, bcl-2, and bax oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer.

1997 • 169 citations

Prognostication of astrocytoma patient survival by Ki‐67 (MIB‐1), PCNA, and S‐phase fraction using archival paraffin‐embedded samples

1994 • 166 citations

Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin.

1997 • 145 citations

Long-Term Survival in Patients with Malignant Astrocytoma

1994 • 129 citations

bcl-2 and apoptosis in lymph node positive breast carcinoma

1998 • 126 citations

Apoptosis in Neurological Disease

1998 • 126 citations

Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: relationships and prognostic value

1997 • 125 citations

Prognostic Significance of Ki-67 Proliferation Index in Supratentorial Fibrillary Astrocytic Neoplasms

1994 • 112 citations

p53-Dependent G1 arrest and p53-independent apoptosis influence the radiobiologic response of glioblastoma

1996 • 104 citations

MDM2 and p53 expression in gliomas: a multivariate survival analysis including proliferation markers and epidermal growth factor receptor

1997 • 100 citations

Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumor-suppressor gene products on survival.

1997 • 96 citations

Epidermal growth factor receptor: An independent predictor of survival in astrocytic tumors given definitive irradiation

1996 • 93 citations

Histologic and non-histologic factors correlated with survival time in supratentorial astrocytic tumors

1985 • 90 citations

Prognostic factors in gliomas. A multivariate analysis of clinical, pathologic, flow cytometric, cytogenetic, and molecular markers

1994 • 88 citations

Lack of prognostic relevance of alterations in the epidermal growth factor receptor—transforming growth factor-α pathway in human astrocytic gliomas

1996 • 83 citations

Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis

1995 • 77 citations

bcl-2 protein expression in tumors of the central nervous system

1994 • 76 citations

Prognostic Implications of p53 Overexpression in Supratentorial Astrocytic Tumors

1994 • 70 citations

Preferential expression of Fas/APO1 (CD95) and apoptotic cell death in perinecrotic cells of glioblastoma multiforme

1996 • 65 citations

Bcl-2 protein expression: association with p53 and prognosis in colorectal cancer

1998 • 62 citations

Apoptosis in cerebral astrocytic tumours and its relationship to expression of the bcl‐2 and p53 proteins

1995 • 60 citations

Apoptosis and mitosis as prognostic factors in pathologically staged N1 nonsmall cell lung cancer

1996 • 60 citations

The Role of Growth Factor Receptors in Central Nervous System Development and Neoplasia

1995 • 51 citations

Molecular Genetics of Nervous System Tumors

1994 • 51 citations

Induction of apoptosis in multi-drug resistant (MDR) human glioblastoma cells by SN-38, a metabolite of the camptothecin derivative CPT-11

1997 • 50 citations

The epidermal growth factor receptor in glioblastoma: genomic amplification, protein expression, and patient survival data in a therapeutic trial.

1995 • 49 citations

Apoptotic Index in Ovarian Carcinoma: Correlation with Clinicopathologic Factors and Prognosis

1997 • 48 citations

Bcl-2 distribution in neuroepithelial tumors: an immunohistochemical study

1996 • 48 citations

Expression of bcl-2 in reactive and neoplastic astrocytes: lack of correlation with presence or degree of malignancy

1995 • 47 citations

Apoptosis in glial tumors as determined by in situ nonradioactive labeling of DNA breaks

1995 • 36 citations

Statistical modelling in analysis of prognosis in glioblastoma multiforme: A study of clinical variables and Ki-67 index

1991 • 34 citations

Correlation of p53 immunoreactivity and sequencing in patients with glioma

1996 • 34 citations

p53 immunohistochemical positivity as a prognostic marker in intracranial tumours

1994 • 32 citations

p53 status has no prognostic significance in glioblastomas treated with radiotherapy.

1997 • 31 citations

Prognostic factors in astrocytomas: relationship of p53, MDM-2, BCL-2 and PCNA immunohistochemical expression to tumor grade and overall patient survival.

1997 • 27 citations

Apoptosis in astrocytic neoplasms

1997 • 27 citations

Induction of apoptosis by EGF receptor in rat mammary adenocarcinoma cells coincides with enhanced spontaneous tumour metastasis.

1996 • 26 citations

A study of apoptosis in brain tumors by in situ end-labeling method.

1996 • 25 citations

Histopathologic and immunohistochemical prognostic factors in malignant gliomas

1997 • 23 citations

Proliferating cell nuclear antigen immunostaining and survival in cerebral astrocytoma

1993 • 21 citations

Proliferating Cell Nuclear Antigen Expression in the Survival of Astrocytoma Patients

1994 • 16 citations

Apoptosis and necrosis occurring during different stages of primary and metastatic tumor growth of a rat mammary adenocarcinoma.

1996 • 12 citations

Localization of apoptotic cells in situ of brain tumors.

1995 • 11 citations

Alteration ofbcl-2 andbax expression in embolized meningiomas

1998 • 8 citations

[Correlation between apoptotic index, bcl-2 protein expression and progression and prognosis in breast carcinoma].

1998 • 6 citations

Apoptosis in tumors of the central nervous system

1997 • 5 citations