Apoptosis in astrocytic neoplasms

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

1994 • 3,536 citations

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

Histological Typing of Tumours of the Central Nervous System

1993 • 1,493 citations

Apoptosis in cancer therapy: Crossing the threshold

1994 • 1,351 citations

p53-Dependent apoptosis suppresses tumor growth and progression in vivo

1994 • 883 citations

bcl-2 inhibits death of central neural cells induced by multiple agents.

1993 • 631 citations

Inhibition of apoptosis during development of colorectal cancer.

1995 • 548 citations

The Bcl-2 Protein: a Prognostic Indicator Strongly Related to p53 Protein in Lymph Node-Negative Breast Cancer Patients

1994 • 461 citations

The clinical assessment of proliferation and growth in human tumours: Evaluation of methods and applications as prognostic variables

1990 • 341 citations

The p53 Gene and Protein in Human Brain Tumors

1994 • 303 citations

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells.

1994 • 290 citations

Comparative Study of p53 Gene and Protein Alterations in Human Astrocytic Tumors

1993 • 229 citations

Differential expression of bcl2 protooncogene in neuroblastoma and other human tumor cell lines of neural origin.

1991 • 222 citations

Ki-67 immunoreactivity in human central nervous system tumors: a study with MIB 1 monoclonal antibody on archival material

1994 • 203 citations

Reduction in apoptosis relative to mitosis in histologically normal epithelium accompanies fibrocystic change and carcinoma of the premenopausal human breast

1992 • 126 citations

Apoptosis and cell proliferation in human neuroepithelial tumors

1995 • 96 citations

Human gliomas with wild-type p53 express bcl-2.

1995 • 94 citations

Cell proliferation patterns in the diagnosis of astrocytomas, anaplastic astrocytomas and glioblastoma multiforme: a Ki‐67 study

1990 • 91 citations

Tumor cell proliferation and apoptosis in medulloblastoma

1994 • 67 citations

Cellular death in neuroblastoma: in situ correlation of apoptosis and bcl‐2 expression

1995 • 66 citations

Apoptosis in cerebral astrocytic tumours and its relationship to expression of the bcl‐2 and p53 proteins

1995 • 60 citations

Expression of bcl-2 in reactive and neoplastic astrocytes: lack of correlation with presence or degree of malignancy

1995 • 47 citations

Detection of DNA strand breaks associated with apoptosis in human brain tumors

1995 • 46 citations

Localization of apoptotic cells in situ of brain tumors.

1995 • 11 citations

Induced expression and subcellular localization of the Bcl-2 protein in cultured glioma cells.

1994 • 5 citations