Subsets of Glioblastoma Multiforme Defined by Molecular Genetic Analysis

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

1985 • 1,523 citations

Histological Typing of Tumours of the Central Nervous System

1993 • 1,493 citations

Grading of astrocytomas: A simple and reproducible method

1988 • 902 citations

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

1987 • 843 citations

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

1992 • 757 citations

Glioblastoma multiforme and anaplastic astrocytoma pathologic criteria and prognostic implications

1985 • 659 citations

Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma

1986 • 524 citations

Clonal genomic alterations in glioma malignancy stages.

1988 • 520 citations

Patient age, histologic features, and length of survival in patients with glioblastoma multiforme

1987 • 388 citations

A simplified classification of the gliomas.

1949 • 349 citations

Specific Chromosomal Abnormalities in Malignant Human Gliomas

1988 • 338 citations

Supratentorial anaplastic gliomas in adults

1989 • 299 citations

p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression.

1992 • 297 citations

p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma.

1992 • 297 citations

Mitotic recombination of chromosome 17 in astrocytomas.

1989 • 288 citations

p53 mutations in human malignant gliomas: comparison of loss of heterozygosity with mutation frequency.

1992 • 248 citations

Comparative Study of p53 Gene and Protein Alterations in Human Astrocytic Tumors

1993 • 229 citations

Altered Expression of the Retinoblastoma Gene Product in Human Sarcomas

1990 • 221 citations

Gene Amplification in Malignant Human Gliomas: Clinical and Histopathologic Aspects

1988 • 216 citations

Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme

1992 • 215 citations

Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas.

1992 • 212 citations

Amplification of Epidermal Growth Factor Receptor Gene in Gliomas: Histopathology and Prognosis

1992 • 201 citations

Allelotype of human malignant astrocytoma.

1990 • 163 citations

Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas.

1992 • 161 citations

Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas.

1989 • 153 citations

TP53 Gene Mutations and 17p Deletions in Human Astrocytomas

1991 • 137 citations

Loss of heterozygosity for loci on chromosome 17p in human malignant astrocytoma.

1989 • 116 citations

Analysis of c-erbB-2 expression in breast carcinomas with clinical follow-up.

1989 • 115 citations

Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme

1989 • 109 citations

Prognostic factors for patients with brain tumors.

1977 • 105 citations

Loss of constitutional heterozygosity in chromosome 10 in human glioblastoma

1990 • 40 citations

Tumors of the Central Nervous System

1953 • 38 citations

Allelic losses at chromosome 17p in human renal cell carcinoma are inversely related to allelic losses at chromosome 3p.

1992 • 37 citations

Neuroblastoma ‐Clinical Applications of Molecular Parameters

1990 • 35 citations