bcl-2 protein expression in tumors of the central nervous system

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections.

1991 • 2,598 citations

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1993 • 1,692 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1991 • 1,223 citations

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma.

1986 • 1,118 citations

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1991 • 1,090 citations

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer.

1992 • 1,063 citations

Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes.

1993 • 1,044 citations

Molecular regulation of apoptosis: Genetic controls on cell death

1993 • 923 citations

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA

1993 • 758 citations

Antigen unmasking on formalin‐fixed, paraffin‐embedded tissue sections

1993 • 733 citations

bcl-2 inhibits death of central neural cells induced by multiple agents.

1993 • 631 citations

The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis

1993 • 586 citations

Expression of bcl-2 in fetal tissues suggests a role in morphogenesis.

1993 • 320 citations

Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis.

1993 • 275 citations

BCL‐2 expression in adult and embryonic non‐haematopoietic tissues

1993 • 265 citations

Expression of the apoptosis-suppressing protein bcl-2, in neuroblastoma is associated with unfavorable histology and N-myc amplification.

1993 • 262 citations

Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

1994 • 251 citations

bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways.

1993 • 238 citations

Correlations between apoptotic and proliferative indices in malignant non-Hodgkin's lymphomas.

1993 • 222 citations

Differential expression of bcl2 protooncogene in neuroblastoma and other human tumor cell lines of neural origin.

1991 • 222 citations

Bcl‐2 proto‐oncogene expression in epstein‐barr‐virus‐associated nasopharyngeal carcinoma

1993 • 198 citations

Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells.

1993 • 144 citations

Bcl-2 affects survival but not neuronal differentiation of PC12 cells

1993 • 129 citations

Apoptosis in the Anterior Pituitary Gland of the Rat: Studies with Estrogen and Bromocriptine

1993 • 87 citations

Lectin Binding and bcl-2 Protein Expression in Craniopharyngiomas

1994 • 3 citations